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EMHJ-Eastern Mediterranean Health Journal. 2013; 19 (9): 807-811
in English | IMEMR | ID: emr-159195

ABSTRACT

To evaluate the need for congenital rubella syndrome prevention in our national health programme we aimed to determine the rate of anti-rubella positivity in umbilical cord blood samples 8 years after measles–rubella mass vaccination in the Islamic Republic of Iran. In a cross-sectional study we tested umbilical cord blood samples for anti-rubella IgG and IgM by ELISA in 154 deliveries at a university hospital in Tehran. Overall 72.7% of umbilical cord blood samples were positive for anti-rubella IgG and 27.3% were negative. All of the samples were negative for anti-rubella IgM. In the samples with a history of mothers' rubella vaccination, only 87.5% were positive for anti-rubella IgG. The results suggest the need for another mass vaccination for rubella in women of child-bearing age and continuation of routine vaccination of infants, plus consideration of obligatory anti-rubella IgG testing before pregnancy in women who were not vaccinated and vaccination of women before marriage.


Subject(s)
Humans , Female , Disease Eradication , Cross-Sectional Studies , Fetal Blood , Immunoglobulin G , Immunoglobulin M , Enzyme-Linked Immunosorbent Assay , Vaccination
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