Dependence of quality of thallium - 201 on irradiation data

Thallium-201 is produced through 203Tl [p, 3n] 201pb 201Tl reaction by cyclotron. This radioisotope has known as one of the cyclotron radioisotopes which is used for myocardial perfusion in the coronary artery disease, Tl-201 after chemical purification and quality control in the form of 201Tl-chlorid is ready to send to the hospitals. In this work the effect of the proton energy on quality of Tl-201, was studied. Radionucleidic purity was determined by high purity Ge [HPGe] detector Gamma spectrometer, in production time and after one half-life [73h]. The targets were coated with Enriched Thallium-203 [97%]. The Variation of thickness of targets was 18.3 +/- 1.3micro m. The different energies of bombardment on quality of Tl-201 and Tl-200, Tl-202, and Pb-203 [as impurity] were studied. The results have shown that optimum energy for proton was 28.5 MeV. The variation energy of bombardment can change the purity of Tl-201 but all results were in the standard range according to the United States Pharmacopoeia [USP] and European Pharmacopoeia

Enteral versus parenteral nutrition support following laparotomy in seriously traumatized patients

Polytraumatized patients are characterized by hypercatabolic states with great need for full nutrition for energy supply, host defence, and wound healing. This is a prospective randomized study including 30 seriously injured patients admitted to our hospitals between March 1996 and April 1998. We are comparing the efficacy of total parenteral nutrition [TPN] versus tube feeding jejunostomy. We started nutritional support immediately postoperatively. There were no significant differences between the two groups as regards age, sex, injury severity score [ISS], and mechanism of injury. Daily caloric intake, nitrogen intake, and nitrogen balance were statistically comparable in both groups. The results showed that pre-and post-nutrition weight, biochemical investigations and body parameters were comparable in both groups. Septic complications were lower in tube feeding jejunostomy patients, while abdominal complications were higher in them than TPN group. We suggest that early post-operative feeding jejunostomy is a reliable, safe, simple and cost effective method of nutrition for polytraumatized patients undergoing laparotomy