Effect of honey on tracheobronchial tree of adult male guinea pigs

The effect of honey on the bronchoconstriction induced by histamine [0.5%] and acetylcholine [4%] aerosols in normal conscious guinea pigs, as well as its antianaphylactic effect on sensitized guinea pigs exposed to the antigen [5% ovalbumin aerosol] have been evaluated. Pretreatment with honey [3 g/kg] prolonged the preconvulsive time of normal conscious guinea pigs exposed to histamine, acetylcholine aerosols, or sensitized guinea pigs exposed to the antigen [5% ovalbumin] aerosol. The effect in the latter one is better than the first two types. This denoted that honey can be used for treatment of bronchial asthma due to its antagonistic effect to hypersensitivity reactions

Effect of pretreatment with labetalol on gastric secretions altered by ethanol administration

The present work was carried out on 80 pylorus ligated rats to study the effects of oral 50% ethanol [1 ml/150 g rat] for a period of 3 hours on gastric secretion and the effect of pre-treatment with graded doses of labetalol administered by intraperitoneal [IP] route before oral ethanol on the same parameters. The collected gastric juice was analyzed for volume [ml], titratable acidity [Meq/l], total acid output [Meq/h], pepsin concentration [mg/ml] and glycoprotein content [mg hexose/ml]