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El-Minia Medical Bulletin. 2000; 11 (1): 16-21
in English | IMEMR | ID: emr-53748

ABSTRACT

The aim of this work was to investigate the changes in lipid peroxidase, catalase, superoxide dismutase together with vitamin A and vitamin C in steroid sensitive nephritic syndrome [SSNS]. The study was carried out on 23 children with SSNS in addition to 23 age and sex matched controls. After a thorough history and clinical examination, all were subjected to laboratory investigations including complete urine analysis, serum creatinine, creatinine clearance, plasma proteins, serum albumin, serum cholesterol, blood catalase [Cat], plasma superoxide dismutase [SOD], plasma lipid peroxide, vitamin C and vitamin A levels. The results showed that serum lipid peroxidase was significantly higher in nephrotic children and maximum increase occurred during relapse. Blood catalase superoxide dismutase, vitamins A and C were significantly lower in nephrotic children compared with the control group and the maximal decrease was during relapse. There was a significant positive correlation between serum catalase and SOD and vitamin C in patients with [SSNS]


Subject(s)
Humans , Male , Female , Child , Antioxidants , Kidney Function Tests , Lipid Peroxides , Superoxide Dismutase , Catalase , Vitamin A , Ascorbic Acid
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