ABSTRACT
The wood of the plant Sesbania sesban, is reported to have antinociceptive activity. To validate its folk use in the treatment of pain, wood was extracted successively with petroleum ether, chloroform, ethyl acetate, ethanol, and water to produce respective extracts. The extracts (50 and 100 mg/kg, ip) were screened for antinociceptive activity using hot plate test and acetic acid-induced writhing test in mice. Petroleum ether, chloroform, and ethyl acetate extracts showed significant and dose-dependent activity in both the tests. In order to find out the involvement of opioid receptors, effect of naloxone (1 mg/kg, sc) on the action of extracts was checked in hot plate test. Petroleum ether, chloroform, and ethyl acetate extracts showed significant and dose dependant antinociceptive activity. The antinociceptive action of the extracts was blocked by naloxone, suggesting involvement of opioid receptors in the action.
ABSTRACT
Rhus semialata Murr. (Anacardiaceae) is a deciduous tree of north eastern India. The fruit of this plant is traditionally used to control diarrhoea and dysentery. The Present study was undertaken to evaluate anti-diarrhoeal potency of methanol extract of fruits of R. semialatalts indicated that the methanol extract of the fruits of R. semialata possesses significant anti-diarrhoeal effect and substantiated the use of this herbal remedy as a non-specific treatment for diarrhoea in folk medicine
Subject(s)
Antidiarrheals , Diphenoxylate , Plant Extracts , Rats , RhusABSTRACT
Fine needle aspiration biopsy is now widely used for detection of any pathological lesions like neoplasm, specific inflammation, cysts, etc. In a study of 22 cases, 17 (77.2%) were diagnosed by aspiration. Specific diagnosis was found in 59% cases and in 18.2% cases suggestive diagnosis was confirmed by histopathological examinations from biopsy materials. Like other investigative methods it is accurate and informative. It is also simple, can be done quickly and cheaper economically.