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Asian Pacific Journal of Tropical Biomedicine ; (12): 300-305, 2017.
Article in Chinese | WPRIM | ID: wpr-672993

ABSTRACT

Objective:To identify and isolate the chemical compounds of Phaleria macrocarpa (P.macrocarpa) fruit ethanolic extract.Methods:Dried fruit of P.macrocarpa was extracted with 90% ethanol and partitioned between n-hexane/H2O and ethyl acetate/H2O.The organic layer was fractionated by various stationary phase and identified by using combined data of ID [(proton nuclear magnetic resonance (NMR),carbon-13 NMR)],2D-NMR (heteronuclear multiplequantum correlation and heteronuclear multiple-bond correlation),and mass spectrum.Results:Purification of n-hexane and ethyl acetate fractions from ethanolic extract of P.macrocarpa fruit resulted in isolation of nine compounds.Conclusions:A new compound was isolated and identified as glyceryl pentacosanoate.Also,two xanthones,which are 1,7-dihydroxy-3,6-dimethoxyxanthone and 1,6,7-trihydroxy-3-methoxyxanthone,are firstly reported to be isolated from P.macrocarpa.

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