ABSTRACT
Los tricobezoar son recolecciones de material ingerido (pelos, fibras) que se acumulasn en estómago e intestino. Se originan de la tricotilomanía más tricofagia, cuando el tricobezoar se acumula en duodeno recibe el nombre de Sídrome de Rapunzel, más frecuente en el sexo femenino. Adolescente de 15 años, quien presentó dolor abdominal de aparición insidiosa acompañada de naúseas y vómitos incontables que se irradian a hipocondrio y fosa iliaca izquierda, su evolución fue torpida presentando signos de irritación peritoneal. Se realiza laparatomía exploradora hallándose tumor de contenido de pelo a nivel del Ángulo de Treitz, y cámara gástrica. Siendo egresada y referida al servicio de psiquiatría infanto-juvenil.
Subject(s)
Humans , Adolescent , Female , Albendazole/administration & dosage , Bezoars/diagnosis , Bezoars/pathology , Dehydration/diagnosis , Abdominal Pain/diagnosis , Intestine, Small/pathology , Laparotomy/methods , Metronidazole/administration & dosage , Trichotillomania/pathology , Vomiting/diagnosis , Adolescent Psychiatry , Albendazole/pharmacology , Foreign Bodies , Gastroenterology , Metronidazole/pharmacology , Parasympatholytics/therapeutic useABSTRACT
Amelia es la ausencia de las partes esqueléticas en su totalidad de la extremidades superiores y inferiores. La Amelia total o tetra Amelia es la ausencia total de las cuatro extremidades. La falla en la formación del primordio en etapas tempranas del desarrollo embrionario o una disrupción en el desarrollo normal conllevan a la ausencia de una o mas extremidades. La prevalencia esta alrededor de 0.04-0.15/10000 nacidos. El diagnóstico prenatal se identifica por la ausencia de una o mas extremidades a través de la ultrasonografía. Mútiples defectos orgánicos han sido asociados a la Amelia y su pronóstico depende de la presencia o no de dichas anomalías. Nosotros reportamos nuestra experiencia con un feto diagnosticado por presencia o no de dichas anomalías. Nosotros reportamos nuestra experiencia con un feto diagnosticado por ultrasonografía con tetra-amelia a las 18 semanas y seis días de edad gestacional, con otras anomalías orgánicas.
Subject(s)
Humans , Adult , Female , /physiology , Prenatal Diagnosis/methods , Ectromelia/diagnosis , Ectromelia/genetics , Ectromelia/pathology , Ultrasonography , Cleft Palate , Congenital Abnormalities , Foot Deformities, Congenital/etiology , Microphthalmos , Trisomy/pathologyABSTRACT
Determinar factores de riesgo y modalidades diagnóstico-terapéuticas del Embarazo Ectópico (EE). Estudio descriptivo, analítico de 353 casos de EE. Período 2000-2006. Servicio de Gineco-obstetricia de IAHULA, Estado Mérida, Venezuela. 353 historias con diagnóstico de EE. Grupo predominante: 19-34 años (75,1 por ciento). Nuliparidad (25,5 por ciento). Antecedentes Gineco-obstétricos (27,2 por ciento); Anticonceptivos (45,3 por ciento); ITS (23, 2 por ciento); DIU (10,8 por ciento); Cirugía Ginecológica y/o Abdominal anterior (33,4 por ciento). ß-hCG positivas 94,3 por ciento; Culdocentesis positivas 78,16 por ciento. Hallazgo Ultrasonográfico: 88,33 por ciento, Hallazgo Quirúrgico: 310 casos; localización Tubarica (97,09 por ciento); Salpingectomía total: 84,1 por ciento. El EE es una emergencia obstétrica frecuente, pone en riesgo la vida de la paciente con patogénesis multifactorial.
Subject(s)
Humans , Adult , Female , Pregnancy , Pregnancy, Ectopic/diagnosis , Infertility, Female/history , Laparotomy/methods , Ultrasonics/adverse effects , Pregnancy Complications/diagnosis , Medical RecordsABSTRACT
Se realizó una investigación observacional, descriptiva, presentando la revisión de 3 pacientes con Histerectomía Obstétrica periparto ocurridas en el Hospital Sor Juana de la Cruz en el período 2001-2008. Siendo en el 100 por ciento de los casos el parto por operación cesárea. Las principales causas de interrupción fueron: en cesárea electiva: desproporción cefalo-pélvica en 0,40 por ciento, Útero cicatrizal por cesárea anterior en 1,36 por ciento y en la cesárea de urgencia el Sufrimiento Fetal agudo en el 0,40 por ciento. La principal causa clínica de Histerectomía Obstetricia es la atonia uterina en 2 casos, acretismo placentario en 1 caso (Realizándose la Biopsia y confirmando el diagnóstico). La Histerectomía obstétrica susbtotal se realizó en los 3 casos y solo en 1 caso y salpingooferectomía derecha por estallido ovárico. No se registró muerte materna ni muerte fetal. La mayor proporción de pacientes eran nulípara y con edad gestacional comprendida entre las 39-41 semanas.
Subject(s)
Humans , Female , Cesarean Section/methods , Hysterectomy/methods , Term Birth/physiology , Cephalopelvic Disproportion , Gestational Age , ObstetricsABSTRACT
The fate of pentavalent antimony [Sb v] in different tissues in the body after intramuscular administration is of great interest for the future study of Sb v therapy in different sitting. Pharmacokinetics and tissue distribution of antimony [Sb v] were studied in the hamster after daily dose of sodium stibogluconate equivalent to 120 mg kg -1 of Sb v, administered intramuscularly for two weeks. Liver, spleen, heart, kidney and skin tissues were isolated after blood collection at the specified time. Antimony was measured in these tissues after suitable treatment, ashing and processing, by flameless atomic absorption spectrophotometry. The concentrations of Sb v time profile in blood showed a linear rapid decline with elimination half life [t 1/2] of 1.7 h. The concentration of drug [micro g/gm] declined in a biphasic manner from almost all tissues. However, the concentrations of Sb v were declined in slower fashion from the hamster tissues than from the blood. The maximum concentration of Sb v was determined in the kidney tissues [3416 +/- 631 micro g/gm] while the lowest concentration was in the spleen [209 +/- 187 micro g/gm]. The maximum concentration of Sb v in the kidney [micro g/gm] was more than 25 fold higher than that measured from blood [micro g/ml]. The AUC of Sb v in the studied tissues was in this rank: kidney> liver> skin> spleen > heart > blood. Surprisingly, the heart, spleen and liver showed a similar t 1/2 of 5.2-6.2 h while the kidney and skin had a t 1/2 of about 3 h. Therefore, disposition of Sb v seems to kinetically follow multicompartmental model. The kidneys got the highest concentration of drug which may lead to nephrotoxicity on long term therapy
Subject(s)
Animals , Antimony/metabolism , Antimony Sodium Gluconate/pharmacokinetics , Cricetinae , Leishmaniasis/drug therapy , Injections, IntramuscularABSTRACT
This study included 20 infiltrating duct carcinoma patients, who were tested for serum ferritin before and after post operative radiotherapy. We followed the radiotherapy regimen of NEMROCK. Their values were compared to those of 20 normal controls. Cancer breast patients had significantly higher values of serum ferritin when compared to the control. This was found in both the pre treatment and post treatment groups. However, two to three months after completing radiotherapy, serum ferritin significantly dropped to a level below the pre treatment value. Our results prove that serum ferritin may be used as a reliable marker of tumor burden during the the follow-up of cancer breast patients. It can also be used to assess the radiotherapy effect on the tumor
Subject(s)
Humans , Female , Radiotherapy/adverse effects , Breast , Ferritins/blood , Breast Neoplasms/pathologyABSTRACT
This is a prospective non-randomized trial including 14 patients suffering from unresectable hepatocellular carcinoma who attended Kasr El Aini Center for Radiation Oncology and Nuclear Mcdicine [NEMROCK], from January 1991 till January 1994. All patients received the anti-estrogen Tamoxifen [TAM], as a palliative treatment. The maximum survival was 24 months [two patients], and the minimum survival was three months [five patients]. The maximum duration of subjective response was 18 months, and the minimum duration of subjective response was two months. There was an objective response evidenced by a drop of the median level of serum alpha-fetoprotein. The drop in serum alpha fetoprotein was maintained for 6 months in 12 patients and in two patients, it was maintained for 18 months
Subject(s)
Humans , Female , Carcinoma, Hepatocellular/drug therapy , Palliative Care , Tamoxifen , Liver Function Tests/methodsABSTRACT
Copper, zinc, iron and manganese were evaluated in sera of 20 female cancer breast patients and 20 control females of matching age. Serum copper, iron, copper/zinc ratio and manganese were found to be significantly higher in the cancer breast group when compared to the normal controls. Serum zinc was found to be insignificantly lower in the cancer breast group. Serum iron had the highest sensitivity and specificity among the studied trace elements
Subject(s)
Trace Elements/blood , Breast Neoplasms/pathology , Evaluation StudyABSTRACT
Twenty two patients with nasopharyngeal carcinoma with a documented residual lesion in the nasopharynx at 66 GY [clinically and/or pathologically] were studied. Booster dose 10-14 Gy was given in 14 patients while 8 patients did not receive the boost. The value of booster dose was reflected favourably upon the overall response rate and its duration and on the disease free survival rates. Among 14 patients received the boost, 3 have partial remission for a median 18 months and 11 patients have complete remission for a median 30 months. For the 8 patients left unboosted only one patients maintained a complete remission for 30 months; 3 patients have partial remission for a median 15 months and 4 patients with stationary disease for 12 months. The total local recurrence, rates of both groups of patients were 21.4% [3/14] and 87.5% [7/8], respectively. Local recurrence was relatively high among patients with primary well to moderately differentiated epitheliomas than poorly to un-differentiated ones, even in boosted patients. The disease-free survival rate for the whole study group was 50% at 36 months with a median follow-up period and overall survival of 27 and 14.5 months for the patients with and without primary boosting, respectively. Disease free-survival rate was significantly higher for the boosted than non-boosted patients [80% and 13% at 20 months, respectively], and with 73% disease free-survival at 36 months for the boosted patients. From this-study, we believe that booster dose for residual lesion in the nasopharynx [better pathologically proved] is necessary to improve the local control and the disease-free survival of patients