ABSTRACT
Poor compliance to therapy and antibiotic resistance are the main causes for failure of anti-Helicobacter pylori [H. pylori] therapy. The purpose of this study was to assess the effectiveness of omeprazole-based triple therapy in Iranian children. Fifty-seven children with H. pylori-related gastroduodenal disease received 1-week triple therapy with a combination of omeprazole, amoxicillin and clarithromycin [according to the susceptibility test]. Success of eradication was assessed by [13]C-urea breath test and endoscopy. Sixty-four patients [mean age 11.3 years; range 2.7-16 years] were included. Eradication was successful in 84.2% [95% confidence interval, 72.8% intention to treat]. One-week triple therapy was effective for the eradication of H. pylori infection in children
ABSTRACT
To identify the frequency of voiding dysfunction in patients with functional constipation, dysfunctional voiding soring system (DVSS) was surveyed in 85 patients with functional constipation. Urinalysis, culture and renal ultrasound were performed in all cases. If the child had urinary tract infection, voiding cystourethrography and DMSA scan were performed. Fifty four patients (63.5%) out of 85 had voiding dysfunction (DVSS score above 6 in females and above 9 in males) compared to 28 out of 280 normal children (10%) in control group (P<0.001). Voiding dysfunction symptoms should be examined carefully in patients with functional constipation.