1.
Translational and Clinical Pharmacology
;
: 114-116, 2017.
Article
in English
| WPRIM
| ID: wpr-87968
ABSTRACT
Indoxyl sulfate, a protein-bound uremic toxin, leads to CKD (chronic kidney disease) progression and its complications through the activation of AhR (aryl hydrocarbon receptor) and RAS (renin-angiotensin system). Inhibition of these pathways may slow the development of CKD and CKD-associated complications.