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1.
Rev. enferm. Inst. Mex. Seguro Soc ; 31(4): 122-127, 09-oct-2023. tab
Article in Spanish | LILACS, BDENF | ID: biblio-1518865

ABSTRACT

Introducción: el nivel socioeconómico (NSE) de las familias tiene un papel fundamentan en el desempeño académico de los estudiantes. Durante la pandemia, las familias con NSE bajo tuvieron menores oportunidades y se acrecentaron las desigualdades por limitaciones económicas y técnicas, lo cual pudo haber influido en las calificaciones y rendimiento académico de los alumnos. Objetivo: identificar la relación entre el NSE y el rendimiento académico de un grupo de estudiantes de licenciatura en enfermería durante la pandemia COVID-19. Metodología: estudio transversal, cuantitativo, analítico, con alumnos que tuvieron educación a distancia, se utilizó el instrumento denominado Nivel Socioeconómico (NSE) de la Asociación Mexicana de Agencias de Inteligencia de Mercado y Opinión Pública (AMAI), así como los promedios del semestre cursado en línea Resultados: participaron 167 alumnos, entre las variables de rendimiento académico y nivel socioeconómico se obtuvo un valor de p = 0.961, para las variables de sexo y estado civil se encontró asociación con un valor de p < 0.05. Conclusiones: no se identificó ninguna relación entre las variables del rendimiento académico y el nivel socioeconómico; sin embargo, otras variables como estado civil y sexo dieron significancia estadística, por lo que se sugiere ahondar en estas variables, así como su relación con el rendimiento académico.


Introduction: The socioeconomic level (SES) of families has a fundamental role in the academic performance of students, during the pandemic families with a low SES had fewer opportunities and increased inequalities due to economic and technical limitations, which could influence grades and academic performance. of the students Objective: To identify th e relationship between the SES and aca demic performance of nursing undergraduate students during COVID-19. Methodology: Cross-sectional, quantitative, analytical study with students who had distance education, the instrument called Socioeconomic Level (NSE) of the Mexican Association of Market Intelligence Agencies and Public Opinion (AMAI) was used. and the averages of the semester completed online. Results: 167 students participated, between the variables of academic performance and socioeconomic level a value of p = 0.961 was obtained, for the variables of sex, marital status an association was found with a p value less than 0.05. Conclusions: No relationship was identified between the variables of academic performance and socioeconomic level, however, other variables such as marital status and sex gave statistical significance, so it is suggested to delve into these variables as well as their relationship with academic performance.


Subject(s)
Humans , Male , Female , Adult , Socioeconomic Factors , Education, Nursing, Continuing/statistics & numerical data , Academic Performance/statistics & numerical data , Education, Distance , COVID-19
2.
Acta méd. colomb ; 48(1)mar. 2023.
Article in English | LILACS-Express | LILACS | ID: biblio-1549978

ABSTRACT

Introduction: 10% of acute myocardial infarctions occur with nonobstructive coronary arteries (MINOCA). These myocardial infarctions represent a group of conditions with less than 50% stenosis. The characteristics of the population with MINOCA in the region are unknown. The objective is to characterize the population with MINOCA and identify the factors associated with adverse outcomes. Materials and methods: this was an analytical cohort study which identified various char acteristics of patients with MINOCA at a tertiary care center in Pereira. From January 1, 2019, to December 31, 2020, 1,500 coronary arteriographies were reviewed; 292 met the angiographic criteria for MINOCA and, of these, 163 patients met the inclusion criteria. The primary outcome was a composite of hospitalization for angina/heart failure, reperfusion therapy, and death from cardiovascular causes and from any cause at six months and one year. Results: the median age was 64 years; 54% (n=88) were men. Arterial hypertension was the most prevalent comorbidity (n=100; 61.3%), and the most common electrocardiographic presenta tion was T wave inversion (29.7%; n=47). Altogether, 19.3% (n=28) and 25.5% (n=37) had some outcome at six months and one year. One-year mortality was 5.5%. On multivariate analysis, the initial troponin, moderate to severe aortic regurgitation and right bundle branch block were associ ated with the event. Conclusion: we have presented the Colombian study with the largest cohort of patients with MINOCA, identifying factors associated with adverse outcomes. (Acta Med Colomb 2022; 48. DOI:https://doi.org/10.36104/amc.2023.2742).

3.
J. Transcatheter Interv ; 31: eA20230012, 2023. ilusão.; tab.
Article in English, Portuguese | LILACS-Express | LILACS | ID: biblio-1523949

ABSTRACT

Introdução: As mais novas técnicas de intervenção coronária percutânea em oclusões crônicas podem melhorar o sucesso técnico. Os objetivos deste estudo foram descrever a segurança e a eficácia da técnica de dissecção/reentrada anterógrada como estratégia inicial de revascularização. Métodos: Registro multicêntrico de países latino-americanos (LATAM Chronic Total Occlusion). Analisamos as características iniciais e os desfechos dos casos em que foi empregada dissecção/ reentrada anterógrada como estratégia primária ou de resgate após escalonamento de fios por via anterógrada. Foram excluídos os casos de abordagem retrógrada. Os médicos usaram dissecção anterógrada convencional e técnica de reentrada. Resultados: Dos 1.875 pacientes analisados, em 50 foi planejada a dissecção/reentrada anterógrada, e, em 1.825, foi planejado o escalonamento de fios por via anterógrada primário. Deu-se preferência à dissecção/reentrada anterógrada em pacientes mais idosos e com história de revascularização (revascularização do miocárdio: dissecção/ reentrada anterógrada em 33,3% e escalonamento de fios por via anterógrada primário em 13,4%, com p<0,001; intervenções coronárias percutâneas em 66,6 e 48,8%, respectivamente, com p=0,012). Oclusões crônicas mais longas (30mm [22-41] e 21mm [15-30], p<0,001) e calcificações moderadas ou graves (62 e 42,6%, com p=0,008) foram associadas à seleção da dissecção/reentrada anterógrada primária, ao invés do escalonamento de fios por via anterógrada primário. Houve correlação significativa entre o aumento do escore J-CTO (X2=37, df=5; p<0,001) e o uso da dissecção/ reentrada anterógrada. O escalonamento de fios por via anterógrada primário teve taxa de sucesso de 88,4%, e a dissecção/reentrada anterógrada, de 76,7%. Para o escalonamento de fios por via anterógrada primário e dissecção/reentrada anterógrada de resgate, o uso do dispositivo CrossBoss® foi relacionado às maiores taxas de sucesso (92,3 e 82,7%, respectivamente). Os desfechos a curto prazo foram semelhantes nos grupos. Conclusão: Na América Latina, a técnica de dissecção/ reentrada anterógrada foi segura e efetiva, tanto como estratégia primária quanto de resgate, mesmo quando utilizada em lesões de maior complexidade. O uso de dispositivos específicos foi relacionado a uma maior taxa de sucesso.


Background: The newest techniques of percutaneous coronary interventions for chronic total occlusion may improve technical success. The objectives were to describe safety and efficacy of antegrade dissection and reentry technique as initial revascularization strategy. Methods: A multicenter registry from Latin American countries (LATAM Chronic Total Occlusion). Baseline characteristics and outcomes of cases using antegrade dissection and reentry as primary strategy or bailout of antegrade wire escalation were analyzed. Retrograde approach cases were excluded. Physicians used conventional antegrade dissection and reentry technique. Results: Out of 1,875 patients analyzed, 50 were planned primary antegrade dissection and reentry and 1,825 planned primary antegrade wire escalation. Primary antegrade dissection and reentry was preferred in older patients, with a history of revascularization (coronary artery bypass graft: primary antegrade dissection and reentry in 33.3% and primary antegrade wire escalation in 13.4%; p<0.001; percutaneous coronary interventions in 66.6% and 48.8%, respectively; p=0.012). Longer chronic total occlusions (30mm [22-41] and 21mm [15-30]; p<0.001), moderate or severe calcification (62% and 42.6%; p=0.008) were associated with the selection of primary antegrade dissection and reentry, instead of primary antegrade wire escalation. There was a significant correlation between increasing J-CTO score (X2=37, df=5; p<0.001), and use of primary antegrade dissection and reentry. Primary antegrade wire escalation had a success rate of 88.4%, and primary antegrade dissection and reentry of 76.7%. For primary antegrade wire escalation and bailout antegrade dissection and reentry, the use of the CrossBoss® device was related to the highest rates of success (92.3 and 82.7%, respectively). Short-term outcomes were similar in both groups. Conclusion: In Latin America, antegrade dissection and reentry was safe and effective, both as primary or bailout strategy, even when used for higher complexity lesions. The use of dedicated devices was related to a higher success rate.

5.
Rev. am. med. respir ; 22(2): 177-179, jun. 2022. ilus
Article in Spanish | LILACS, BINACIS | ID: biblio-1441125

ABSTRACT

Se describe el caso de una mujer de 51 años, nunca fumadora y sin antecedentes médico-quirúrgicos de interés, profesora de informática. Fue remitida a consultas de neumología por un estridor espiratorio de dos meses de evolución, que interfería parcialmente en su trabajo, bajo la sospecha de posible asma bronquial. La exploración física únicamente reveló dicho estridor espiratorio


Subject(s)
Female
6.
Rev. méd. Hosp. José Carrasco Arteaga ; 12(2): 92-97, 31-07-2020. Tablas
Article in Spanish | LILACS | ID: biblio-1178705

ABSTRACT

INTRODUCCIÓN: El cáncer colorrectal ocupa el tercer lugar a nivel mundial entre las neoplasias malignas. El tratamiento utilizado depende entre otros factores de la localización, y va desde la escisión local hasta una resección abdominoperineal y se puede acompañar de tratamiento neoadyuvante y adyuvante, dependiendo del estadiaje. Los objetivos de este estudio fueron, determinar el tipo histológico más común del cáncer de recto, establecer el estadio más frecuente del cáncer de recto y conocer el tratamiento quirúrgico más empleado en el cáncer de recto y sus complicaciones. MATERIALES Y MÉTODOS: Se realizó un estudio descriptivo transversal, con un total de 160 pacientes del Servicio de Cirugía digestiva del Hospital SOLCA, Guayaquil ­ Ecuador, durante el período comprendido entre Enero 2011 y Diciembre 2016, diagnosticados de cáncer de recto histológicamente e intervenidos quirúrgicamente. RESULTADOS: El sexo femenino fue el más afectado con 65.7 %, el 63.1% de los pacientes se diagnosticaron en estadio III, el diagnóstico histológico de adenocarcinoma fue el más común (73.7%), se localizó a nivel bajo en el 67.5 % de los pacientes. Se realizó cirugía programada en el 83.7 %, colostomía derivativa en el 48.8 % y las principales complicaciones registradas fueron las relacionadas con la ostomía en el 9.4% de la población. La mortalidad inmediata corresponde al 1.2 % y la tardía corresponde al 8.1 %. CONCLUSIÓN: El presente estudio, permitió evidenciar que el cáncer de recto afectó principalmente a mujeres, a pacientes mayores de 60 años. La mayoría de pacientes se diagnosticaron en estadios avanzados (III), con histología de adenocarcinoma. La colostomía derivativa fue la técnica quirúrgica más utilizada y la mayoría de pacientes con necesidad de terapia neoadyuvante. Las complicaciones más frecuentes fueron las relacionadas con las ostomías.(au)


BACKGROUND: Colorectal cancer is the third most common among malignant neoplasms worldwide. Treatment choice depends on the location of the tumor, among other factors, and varies from local excision to abdominoperineal resection, adjuvant or neoadjuvant therapy can be needed, depending on clinical stage. The purpose of this study was to determine the most common histological type of rectal cancer, establish the most frequent clinical stage at diagnosis, the most common surgical technique and complications. METHODOLOGY: A cross-sectional study was carried out, with 160 patients treated in the digestive surgery service of Hospital SOLCA, Guayaquil ­ Ecuador, between January 2011 and December 2016, with colorectal cancer histologically diagnosed and treated surgically. RESULTS: Female sex was the most affected, with 65.7%, 63.1% of the patients were diagnosed at stage III, adenocarcinoma was the most common histological type (73.7%), the tumor was more frequently located at a low level, in 67.5% of the patients. Surgery was scheduled for 83.7% of the patients, derivative colostomy was the most common surgical procedure for treatment (48.8%), and the most common complications were those related to the ostomy, in 9.4% of the patients. Immediate mortality was 1.2% and late mortality was 8.1%. CONCLUSION: This study evidenced that colorectal cancer affected with more frequency to women, mainly to people over 60 years old. Most of the patients were diagnosed with advanced clinical stage (III) carcinoma, most frequently adenocarcinoma. Derivative colostomy was the procedure of choice for most of the patients, most of them needed neoadjuvant therapy too. The most common postsurgical complications were those related to ostomies.(au)


Subject(s)
Humans , Male , Female , Middle Aged , Rectal Neoplasms , Carcinoma , Colorectal Neoplasms , Adenocarcinoma , General Surgery , Diagnosis
7.
Oncología (Guayaquil) ; 29(1): 45-53, 30 de abril 2019.
Article in Spanish | LILACS | ID: biblio-1000442

ABSTRACT

Introducción: El cáncer colorrectal (CCR) es la segunda neoplasia más común después del cáncer gástrico, y con frecuencia desarrolla metástasis hepática. Se presenta un estudio unicéntrico del abordaje quirúrgico, resultados y sobrevida pacientes sometidos a cirugía más tratamiento sistémico de metástasis hepáticas de CCR. Métodos: Se realizó un estudio retrospectivo y descriptivo en el Instituto Oncológico del Ecuador de Solca- Guayaquil desde enero del 2015 a diciembre del 2018. Se incluyeron todos los pacientes del Servicio de Laparoscopía operados por cáncer colorrectal, como diagnóstico inicial, que durante sus controles periódicos presentaron metástasis hepáticas y fueron candidatos para tratamiento quirúrgico de metastasectomias, previa valoración con comités de tumores de tubo digestivo. Resultados: La muestra final incluyó 6 pacientes a quienes se les pudo realizar metastasectomías hepáticas anatómicas y no anatómicas. La edad media fue 60 años, con predominio del sexo femenino (n=4, 66.6%). Las lesiones hepáticas se presentaron en un solo segmento hepático en el 66% a las que se les realizo resección total, y cuyas complicaciones presentadas fueron del 33 %, que se resolvieron durante la estancia hospitalaria. Un paciente recibió neoadyuvancia, y solo un paciente presentó metástasis metacrónica. La sobrevida es del 100% hasta la finalización del estudio. Conclusión: Las decisiones multidisciplinarias sobre una oportuna indicación de metastasectomía hepática, disminuyen la morbimortalidad e incrementan la sobrevida de los pacientes con metástasis hepáticas de cáncer colorrectal.


Introduction: Colorectal cancer (CRC) is the second most common neoplasm after gastric cancer, and with the frequency of liver metastases. We present a unicentric study of the surgical approach, results and survival, patients, surgery and systemic treatment of hepatic metastases of CRC. Methods: A retrospective and descriptive study was carried out at the Oncology Institute of Ecuador in Solca- Guayaquil from January 2015 to December 2018. All patients of the Laparoscopic Service operated by colorectal cancer were included as initial diagnosis, which during their controls newspapers presented liver metastases and were candidates for surgical treatment of metastasectomies, previous valuation with digestive tract tumors committees. Results: The final sample included 6 patients who could undergo anatomical and non-anatomical hepatic metastasectomies. The average age was 60 years, with a predominance of females (n = 4, 66.6%). Hepatic lesions were present in a single hepatic segment in 66% of those who underwent total resection, and whose complications were 33%, which were resolved during the hospital stay. One patient received neoadjuvant therapy, and only one patient presented metachronous metastasis. Survival is 100% until the end of the study. Conclusion: Multidisciplinary decisions on a timely indication of hepatic metastasectomy reduce morbidity and mortality and increase the survival of patients with hepatic metastases of colorectal cancer.


Subject(s)
Humans , Colorectal Neoplasms , Hepatectomy , Liver , General Surgery , Liver Neoplasms , Neoplasm Metastasis
8.
Rev. méd. Hosp. José Carrasco Arteaga ; 10(2): 116-120, Jul 2018. Tablas, Gáficos
Article in Spanish | LILACS | ID: biblio-1000247

ABSTRACT

INTRODUCCIÓN: El cáncer de pene en todo el mundo tiene una incidencia del 0.51- 8.3 por 100 000 varones. Su tratamiento puede ser quirúrgico, conservador o radical, con tratamiento adyuvante radioterapia y quimioterapia. Los objetivos fueron determinar histológicamente el tipo de cáncer de pene más común, el lugar de afectación, y el tratamiento quirúrgico más empleado. MÉTODOS: Es un estudio descriptivo, retrospectivo realizado en el Instituto Oncológico Nacional Dr. Juan Tanca Marengo, en el período de enero del 2010 a diciembre del 2015. Se incluyó a los pacientes con diagnóstico histopatológico de cáncer de pene; las variables estudiadas fueron edad, localización, presencia de ganglios, histopatología, recidiva, metástasis y cirugía realizada; se obtuvo la media y desviación estándar. Para el análisis estadístico se utilizó Excel 2016 y SPSS. RESULTADOS: Los pacientes estudiados fueron 58 con cáncer de pene; se evidenció, en relación a la edad se obtuvo una media de 59 años y desviación estándar +/-14.74. La lesión se localizó con mayor frecuencia en el glande 41 %, seguido de una afectación total del pene con un 38 %; en el caso de los ganglios fueron palpables en 24 pacientes. El tipo histológico más frecuente fue el carcinoma epidermoide 67 %. El tratamiento más empleado fue la penectomía subtotal en el 62 %. CONCLUSIONES: Se determinó que el carcinoma epidermoide fue el tipo histológico más prevalente, localizándose principalmente en el glande; la técnica más empleada fue penectomía subtotal. Se recomienda acudir precozmente cuando se evidencia una lesión a nivel del pene, el tratamiento precoz de estas lesiones mejoran el pronóstico del paciente.


BACKGROUND: Penis cancer worldwide has an incidence of 0.51- 8.3 per 100 000 males. It is treatment can be surgical, conservative or radical, with adjuvant treatment radiotherapy and chemotherapy. The objectives were: to determine histologically the most common type of penile cancer, the place of involvement, and the most used surgical treatment. METHODS: It is a descriptive, retrospective study realized in Dr. Juan Tanca Marengo National Oncological Institute, between the periods of January 2010 to December 2015. Patients with a histopathological diagnosis of penile cancer were included; the variables studied were age, location, presence of lymph nodes, histopathology, recurrence, metastasis and surgery performed; the mean and standard deviation were obtained. For the statistical analysis Excel 2016 and SPSS were used. RESULTS: The patients studied were 58 with penile cancer; it was evidenced, in relation to age, an average of 59 years and standard deviation was obtained +/- 14.74. The lesion was located more frequently in the glans 41 %, followed by a total involvement of the penis with 38 %; in the case of the nodes they were palpable in 24 patients. The most frequent histological type was squamous cell carcinoma 67 %. The most used treatment was subtotal penectomy in 62 % CONCLUSIONS: It was determined that squamous cell carcinoma was the most prevalent histological type, being located mainly in the glans; the technique most used was subtotal penectomy. It is recommended to pay attention early when there is evidence of a lesion at the level of the penis, the early treatment of these lesions improves the patient's prognosis.


Subject(s)
Humans , Male , Penile Neoplasms/surgery , Penile Neoplasms/classification , Carcinoma, Squamous Cell , Neoplasm Metastasis
9.
Rev. méd. Hosp. José Carrasco Arteaga ; 9(3): 261-265, Nov. 2017. Tablas, Gáficos
Article in Spanish | LILACS | ID: biblio-1005774

ABSTRACT

INTRODUCCIÓN: La patología mamaria afecta a países desarrollados y subdesarrollados, los factores más importantes son los factores ginecológicos, el estilo de vida, los factores ambientales y los antecedentes familiares. La finalidad del tratamiento de cáncer de mama es extraer el tumor y conservar la mayor cantidad de tejido mamario (oncoplastia) debido a que es una zona erógena y físicamente representa la sensualidad humana. Los objetivos de este estudio, fueron: Determinar el tipo histológico más común en el cáncer de mama. Establecer el estadio más frecuente en mujeres con cáncer de mama. Identificar los pacientes que recibieron tratamiento neoadyuvante y adyuvante. Conocer los pacientes que presentan recidiva local o metástasis a distancia por cáncer de mama. MÉTODOS: Se realizó un estudio descriptivo retrospectivo en 407 casos del Servicio de Mastología del Hospital de SOLCA Dr. Juan Tanca Marengo, Guayaquil - Ecuador. Durante el período comprendido entre enero de 2010 y diciembre de 2016, en el que las variables de edad, histopatología, etapa, adyuvancia, neoadyuvancia, recaída, metástasis y muerte. RESULTADOS: Los 407 pacientes estudiados, 235 pacientes se encuentran entre 45 - 64 años, el tipo histológico más común es el carcinoma ductal infiltrante con 360 casos, el estadio más común fue el estadio I con 218 casos, 386 casos recibieron tratamiento adyuvante, 268 casos no recibieron tratamiento neoadyuvante, 24 casos presentaron recidiva local, 22 casos presentaron metástasis a distancia y 295 casos se mantienen en controles periódicos CONCLUSIONES: Los 407 pacientes tratados con cirugía conservadora según el tipo histológico más común de presentación fue el carcinoma ductal infiltrante con el 88 %, el tratamiento neoadyuvante juega un papel muy importante en el manejo de estos pacientes que inicialmente no pueden ser tratados quirúrgicamente, un bajo porcentaje de pacientes presenta recidivas locales o metástasis a distancia pudiendo evitar este tipo de complicaciones con un adecuado seguimiento.


BACKGROUND: Breast diseases affect developed and underdeveloped countries, the most importantfactors being gynecologicalfactors, lifestyle, environmentalfactors and family history. The purpose of breast cancer treatment was to remove the tumor and retain the largest amount of breast tissue(oncoplasty)becauseitisanerogenous zoneandphysically representshumansensuality. The aims ofthis study were to: Determine themost common histologicaltype in breast cancer. Establish the most common stage in women with breast cancer. Identify patients who received neoadjuvant and adjuvant treatment. To know the patients who present local recurrence or distant metastases due to breast cancer. METHODS: A retrospectivedescriptive studywas carriedoutin407 casesoftheMastology Serviceof SOLCA Dr. Juan Tanca Marengo Hospital, Guayaquil - Ecuador. During the period between January 2010 and December 2016, in which the variables of age, histopathology, stage, adjuvant, neoadjuvant,relapse,metastasis and death. RESULTS: The 407 patients that were studied, 235 patients are between 45-64 years old, the most commonhistologicaltypewas infiltratingductal carcinomawith360 cases,themost commonstage was stage I with 218 cases, 386 cases received adjuvanttreatment, 268 cases did notreceive neoadjuvant treatment, 24 cases had local recurrence, 22 cases had distant metastases and 295 cases remained in periodic controls. CONCLUSIONS: The 407 patients treatedwith conservative surgeryaccording to themost common histological type of presentation were infiltrating ductal carcinoma with 88 %, neoadjuvant treatment plays a very importantrole in themanagement ofthese patients who initially cannot be treated surgically, a low percentage of patients present local recurrences or distant metastases, being able to avoid this type of complications with an adequate follow-up


Subject(s)
Humans , Female , Breast Neoplasms/classification , Mastectomy/methods , Chemotherapy, Adjuvant , Neoplasm Metastasis
10.
Oncología (Guayaquil) ; 27(2): 142-155, Ago. 30, 2017.
Article in Spanish | LILACS | ID: biblio-998634

ABSTRACT

Introducción: El rol de la cirugía y la adyuvancia con quimio y radio terapia influyen en la supervivencia y el control local de los sarcomas de partes blandas, por lo que el objetivo del presente estudio fue describir la asociación estadística en un grupo de pacientes con sarcomas de partes blandas tomando en cuenta el tamaño tumoral y la presencia de bordes libres. Métodos: El presente estudio retrospectivo, fue realizado desde enero 2008 a diciembre 2016 en el hospital Solca-Guayaquil, se incluyeron todos los casos de sarcoma de partes blandas. Las variables fueron el diagnóstico histopatológico, el tamaño tumoral, los bordes quirúrgicos, la manipulación previa, la supervivencia y la presencia de recidiva local y/o a distancia. Resultados: Fueron 156 casos, 84 hombres (54 %), de 41 a 60 años 49 casos (31 %). Liposarcoma 40 casos (25.6 %), Leimiosarcoma 25 casos (16 %), Sarcoma pleomórfico 19 casos (12.2%). Localizados en el miembro inferior 70 casos (44.9 %). El tamaño del sarcoma de 9.1 a 16 cm tuvo un Odds Ratio de 3.18 (IC95 1.26 a 7.98) P =0.01. La supervivencia fue igual entre los pacientes con y sin bordes libres Mantel-Cox P =0.26. La adyuvancia en los pacientes sin metástasis fue en 51 casos (53.1 %) y en los pacientes con metástasis fue de 48 (80 %) P<0.001. La adyuvancia en los pacientes sin recidiva fue en 47 casos (54.7 %), en los pacientes con recidiva 52 casos (74.3 %) P =0.013. La manipulación en el grupo sin recidiva fue de 9 casos (10.5 %), en el grupo con recidiva 20 casos (28.6 %) P =0.006. Conclusión: En el presente estudio los factores que influyen negativamente en el control local y sistémico de los sarcomas fueron: los tumores de tamaño de 9.1 a 16 cm, el tratamiento de Adyuvancia con Quimioterapia o Radioterapia y la manipulación previa.


Introduction: The role of surgery and adjuvance with chemo and radio therapy influence the survival and local control of soft tissue sarcomas, so the aim of the present study was to describe the statistical association in a group of patients with sarcomas of soft tissues taking into account the tumor size and the presence of free edges. Methods: The present retrospective study was carried out from January 2008 to December 2016 at the SOLCA-Guayaquil hospital, including all cases of soft tissue sarcoma. The variables were histopathological diagnosis, tumor size, surgical margins, previous manipulation, survival and the presence of local and / or distant recurrence. Results: There were 156 cases, 84 men (54 %), 41 to 60 years 49 cases (31%). Liposarcoma 40 cases (25.6 %), Leimiosarcoma 25 cases (16 %), pleomophic sarcoma 19 cases (12.2 %). Located in the lower limb 70 cases (44.9 %). The size of the sarcoma from 9.1 to 16 cm had an Odds Ratio of 3.18 (IC95 1.26 to 7.98) P = 0.01. Survival was equal between patients with and without free edges MantelCox P = 0.26. Adjuvance in patients without metastasis was 51 cases (53.1 %) and in patients with metastasis was 48 (80 %) P <0.001. Adjuvance in patients without recurrence was 47 cases (54.7 %), in patients with recurrence 52 cases (74.3 %) P = 0.013. The manipulation in the group without recurrence was 9 cases (10.5 %), in the group with recurrence 20 cases (28.6 %) P = 0.006. Conclusion: In the present study the factors that negatively influence the local and systemic control of sarcomas were: tumors of size from 9.1 to 16 cm, Adjuvant treatment with Chemotherapy or Radiotherapy and previous manipulation.


Subject(s)
Humans , Sarcoma , Sarcoma, Ewing , Sarcoma, Alveolar Soft Part , Survival Analysis , Sarcoma, Endometrial Stromal , Neoplasm Metastasis
11.
Rev. ADM ; 73(2): 65-71, mar.-abr. 2016. ilus, tab
Article in Spanish | LILACS | ID: lil-789836

ABSTRACT

Objetivo: evaluar la capacidad de BiodentineTM para resistir la microfiltración cuando es usado como material de retroobturación medianteun sistema de transporte de fluidos computarizado. Metodología: En este estudio se utilizaron 60 raíces de dientes unirradiculares, se instrumentaron y obturaron con el sistema de cono único estandarizadodel sistema ProTaper (Dentsply, Maillefer, Suiza) con ultrasonido,utilizando el sellador de conductos radiculares Silco (Silva-Collyan SLP,México). Se hizo la preparación de la cavidad retrógrada con ultrasonidoutilizando la punta E31D del sistema Retro Kit (NSK Company, Japón),con un diámetro de 2 mm. Se llevó a cabo la retroobturación con cada uno de los cementos a evaluar; grupo 1: bturados con Biodentine™ (Septodont, Francia), grupo 2: obturados con MTA Gris (Angelus™, Londrina PR, Brasil), grupo 3: control. Se utilizó un software creado específi camente para evaluar microfi ltración; éste, por medio de sensores infrarrojos, detecta la variación de voltaje de una burbuja de aire dentro de un capilar. El programa expresa el tiempo que tarda la burbuja en pasar por el segundo sensor (mm/min), los cuales se convierten a μL/min, para después expresarlos en unidades de fi ltración, realizándosemediciones en un solo lapso. Resultados: La evaluación en este estudio de la microfi ltración apical de Biodentine™ y MTA Gris Angelus™, arrojó resultados favorables para ambos; se comprobó que no existe diferencia signifi cativa en cuanto a la microfiltración entre ellos; sin embargo, ambos materiales mostraron diferentes características en cuanto a su manipulación, tiempo de fraguado y porosidad. No se presentódiferencia estadísticamente significativa entre los grupos (p = 0.256) U Mann-Whitney y Kruskal Wallis. Conclusión: El Biodentine™ y TA Gris AngelusTM presentan un comportamiento óptimo para la obturación retrógrada. Se requiere realizar otros estudios en cuanto a la interfase con la estructura dentinaria.


Objective: To evaluate, using computational fl uid dynamics, the ability of BiodentineTM to resist microleakage when used as a retro-sealing material. Methodology: In this study, 60 single-rooted teeth were used, which were biomechanically prepared and fi lled using the standardized ProTaper single-cone technique (Dentsply, Maillefer, Switzerland) and ultrasound, using Silco root-canal sealer (Silva-Collyan, SLP, Mexico). The retrograde cavity was prepared using ultrasound and a Retro Kit (NSK Company, Japan) E31D 2 mm-diameter tip. Retrograde fi lling was performed using each of the sealers to be evaluated, as follows: group 1: sealed with BiodentineTM (Septodont, France); group 2: sealed with Grey MTA (AngelusTM, Londrina PR, Brazil); group 3: control. A specially designed software was used, which measures microleakage by using infrared sensors to detect changes in voltage in an air bubble within a capillary tube. The software expresses the time it takes (mm/min) for the bubble to pass through the second sensor, then converts these measurements into μL/min to express the rate of leakage. All of the measurements are taken considering a single interval. Results: The results of the evaluation of the apical microleakage of BiodentineTM and MTA Grey AngelusTM obtained in this study were, in both cases, favorable, proving that there is no signifi cant difference between the two in this respect. However, the characteristics of each in terms of their handling, setting time, and porosity differed. No statistically signifi cant difference between the Mann-Whitney U group and the Kruskal-Wallis group was found (p = 0.256). Conclusion: The performance of Bio-dentineTM and Gray MTA AngelusTM is ideal for retrograde fi lling pur-poses. Further studies are needed, including SEM analysis, in order to determine the quality of the seal, with respect to the interface formed with the dentin structure.


Subject(s)
Dental Leakage/diagnosis , Root Canal Filling Materials/chemistry , Retrograde Obturation , Equipment Design , Materials Testing , Porosity , Data Interpretation, Statistical , Tooth Apex
12.
Med. leg. Costa Rica ; 32(1): 114-118, ene.-mar. 2015.
Article in Spanish | LILACS | ID: lil-753636

ABSTRACT

El arsénico (As) es un elemento considerado como ubicuo, cuyas fuentes pueden ser naturales o productos de la actividad humana. La exposición a este elemento ocurre principalmente por la vía oral. Las presentaciones inorgánicas del As son consideradas como las más tóxicas. La absorción del As ocurre en el intestino delgado y por medio de acuaporinas ingresa a los hepatocitos, en casos de ingesta crónica el As tiende acumularse en hígado, riñones, corazón, sistema nervioso, pulmones, músculo, tracto gastrointestinal y bazo. El consumo crónico de agua con concentraciones de As por encima del valor de referencia dado por la Organización Mundial de la Salud (OMS) ha demostrado un aumento del riesgo de accidentes vasculares cerebrales (AVC), hipertensión arterial (HTA), aterosclerosis carotidea, enfermedades arteriales periféricas, mortalidad por infarto agudo del miocardio (IAM), aumento en enfermedades cardiovasculares en la población pediátrica y diabetes mellitus tipo II.


Arsenic (As) is an element considered as ubiquitous. Its sources may be natural or manmade. The exposure to this element occurs mainly orally. Inorganic ‘As’ presentations are considered the most toxic. Arsenic absorption occurs in the small intestine, and through aquaporin, entering hepatocytes in chronic intake tends. The element (As) tends to get accumulated in the liver, kidneys, heart, nervous system, lung, muscle, gastrointestinal tract, and spleen. Chronic consumption of water with arsenic concentrations above the reference value given by the World Health Organization has shown an increased risk of cerebrovascular accident (CVA), Hypertension (HT), carotid atherosclerosis, peripheral arterial disease, mortality from acute myocardial infarction (AMI), increased cardiovascular disease in the pediatric population, and type II diabetes mellitus.


Subject(s)
Humans , Arsenic , Cardiovascular Abnormalities
13.
Med. leg. Costa Rica ; 32(1): 119-124, ene.-mar. 2015.
Article in Spanish | LILACS | ID: lil-753637

ABSTRACT

El síndrome de Burnout fue declarado en el año 2000 por la Organización Mundial de la Salud como un factor de riesgo laboral por su capacidad para afectar la calidad de vida, salud mental e incluso hasta poner en riesgo la vida. Su definición no se encuentra en el DSM-V, ni en el CIE 10, pero usualmente se describe como una forma inadecuada de afrontar el estrés crónico, cuyos rasgos principales son el agotamiento emocional, la despersonalización y la disminución del desempeño personal. En Costa Rica se han realizado pocos estudios para determinar la incidencia del síndrome de desgaste en personal médico del país, los cuales han contado con muestras pequeñas y han arrojado porcentajes que van desde el 20% hasta el 70%.


Burnout syndrome was declared in 2000 by the World Health Organization as an occupational risk factor for its ability to affect the quality of life, mental health and even life threatening. Its definition is not in the DSM-V, or the ICD- 10, but is usually described as an inadequate way to deal with chronic stress, whose main features are emotional exhaustion, depersonalization and reduced personal performance. In Costa Rica there have been few studies to determine the incidence of burnout syndrome in medical staff in the country, which have had small samples and have yielded percentages ranging from 20% to 70%.


Subject(s)
Humans , Male , Adult , Burnout, Professional , Mental Fatigue
14.
Mem. Inst. Oswaldo Cruz ; 97(8): 1157-1163, Dec. 15, 2002. ilus, tab
Article in English | LILACS | ID: lil-326328

ABSTRACT

In this study, the use of Mtp-40 and alpha antigen polymerase chain reaction (PCR) amplification fragments for the precise tuberculosis (TB) diagnosis was evaluated. One hundred and ninety two different samples were obtained from 113 patients with suspected TB. Mtp-40 and alpha antigen protein genes were amplified by the PCR technique and compared to both the "gold standard" (culture) test, as well as the clinical parameters (including a clinical record and X-ray film exam in 113 patients). Thirty-eight of the 113 patients had a presumptive clinical diagnosis of TB; 74 percent being detected by PCR technique, 58 percent by culture and 44 percent by direct microscopic visualization. Weconclude that it is possible to use PCR as a suitable technique for the detection of any mycobacteria by means of the alpha antigen product, or the specific infection of Mycobacterium tuberculosis by means of the mtp-40 gene. This might be a good supporting tool in difficult clinical TB diagnosis and pauci-bacillary cases


Subject(s)
Humans , Antigens, Bacterial , Bacterial Proteins , Mycobacterium tuberculosis , Tuberculosis , Antigens, Bacterial , Bacterial Proteins , Colombia , Evaluation Study , Gene Amplification , Mycobacterium tuberculosis , Polymerase Chain Reaction , Sensitivity and Specificity
15.
Mem. Inst. Oswaldo Cruz ; 96(6): 835-838, Aug. 2001. ilus
Article in English | LILACS | ID: lil-298594

ABSTRACT

Differential display technique was applied in order to identify transcripts which are present in axenic amastigotes but not in promastigotes of the Leishmania panamensis parasites. One of them was cloned and the sequence reveals an open reading frame of 364 amino acids (aprox. 40 kDa). The deduced protein is homologous to the serine/threonine protein kinases and specially to the mitogen activates protein kinases from eukaryotic species. Southern blot analysis suggest that this transcript, named lpmkh, is present in the genome of the parasite as a single copy gene. These results could imply that lpmkh could be involved in the differentiation process or the preservation of amastigotes in axenic conditions


Subject(s)
Animals , Leishmania/genetics , RNA, Messenger/genetics , Amino Acid Sequence , Blotting, Southern , Germ-Free Life , Molecular Sequence Data
16.
Acta méd. colomb ; 17(1): 63-7, ene.-feb. 1992. ilus, tab
Article in Spanish | LILACS | ID: lil-183212

ABSTRACT

Se describe el caso de una mujer joven atendida en el hospital San Ignacio (Santa Fe de Bogotá), con diagnostico post mortem de síndrome de Reye. Seguidamente, se revisan y discuten los aspectos fisiopatológicos y los concernientes al diagnóstico y la terapéutica.


Subject(s)
Humans , Female , Adult , Influenza B virus/pathogenicity , Reye Syndrome/complications , Reye Syndrome/diagnosis , Reye Syndrome/epidemiology , Reye Syndrome/etiology , Reye Syndrome/physiopathology , Reye Syndrome/mortality , Reye Syndrome/pathology , Reye Syndrome/drug therapy , Reye Syndrome/therapy
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