ABSTRACT
Objective To evaluate the clinical efficacy of dexamethasone in the treatment of severe pregnancy induced hypertension with thrombocytopenia syndrome .Methods 50 cases of severe pregnancy induced hypertension with thrombocytopenia syndrome were selected .The patients were randomly divided into the magnesium sulfate group and dexamethasone group according to the digital table ,25 cases in each group.The magnesium sulfate group was given magnesium sulfate treatment,the dexamethasone group was treated with dexamethasone .The treatment effect,the neonatal mortality rate,premature delivery rate,neonatal asphyxia rate,cesarean section rate,incidence of symptoms and prognosis were compared between the two groups .Results The effective rate of the dexamethasone group (92%) was higher than that of the magnesium sulfate group (68%,χ2 =5.164,P <0.05).The incidence rate of concurrent symptoms in the dexamethasone group (4%) was significantly lower than that in the magnesium sulfate group (20%,χ2 =4.287,P <0.05).The liver function recovery time,ALT recovery time,platelet recovery time in the dexametha-sone group were (3.12 ±1.23)d,(2.09 ±0.26)d,(2.45 ±0.25)d,respectively,which were obviously shorter than those in the magnesium sulfate group (t =3.011,3.872,3.456,all P <0.05).Conclusion Dexamethasone in the treatment of severe pregnancy induced hypertension with thrombocytopenia syndrome has prominent treatment effect , the neonatal mortality,premature birth,neonatal asphyxia rate,cesarean section rate and incidence rate of complica-tions are low,the prognosis is good,it is worthy of further study.
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Objective To compare and analyze the effect of dinoprostone misoprostol and oxytocin in cervical ripening and labor induction.Methods 120 pregnant women in labor in our hospital from January 2015 to January 2017 were selected as the object in this study, all pregnant women were randomly divided into 3 groups, respectively dinoprostone group, misoprostol group and oxytocin group, 40 pregnant in each group., Dinoprostone was placed in vaginal fornix in dinoprostone group;misoprostol was placed in vaginal fornix in misoprostol group;Oxytocin was injected in oxytocin group.The delivery time, rupture time of fetal membranes, labor time and successful rate of induced labor in the 3 groups were compared.Results The dinoprostone group after treatment in pregnant women take delivery time,time and labor rupture time were significantly shorter than the other two groups(P<0.05),the difference was statistically significant;dinoprostone group of pregnant women, the success rate was significantly higher than that of oxytocin group, compared between the two groups(P<0.05),with statistical significance difference;dinoprostone group did not appear abnormal, less adverse reaction.Conclusion Dinoprostone used for cervical ripening and labor induction, the effect is significant, compared with misoprostol and oxytocin, less adverse reaction, high safety, and is worthy of popularization and application.
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Objective To observe the clinical curative effect of Gong Yanping capsule combined with recombinant human interferon α2b vaginal effervescent tablets in the treatment of human papillomavirus infection.Methods80 cases of patients with cervical HPV infection in Xiangshan hospital of traditional Chinese medicine from May 2014 to May 2016 were selected, these patients were divided into Gong Yanping capsule combined with interferon treatment group (combined treatment group, 40cases) and pure Gongyanping capsule treatment group (single treatment group, 40cases) two groups according to the treatment methods, the clinical curative effects, HPV-DNA levels, HPV infection status, incidences of adverse reactions of the two groups were statistically analyzed.ResultsThe clinical total efficiency of the combined treatment group 95% (38/40) was significantly higher than the single treatment group 80% (32/40) (P<0.05), the HPV-DNA level was significantly lower (P<0.05), the HPV infection negative rate 1 months after treatment 2.5% (1/40) was significantly lower than the single treatment group 10% (4/40) (P<0.05), the negative rates 2 months, 3 months after treatment 67.5% (27/40), 97.5% (39/40) were significantly higher than the single treatment group 40% (16/40), 77.5% (31/40) (P<0.05);The difference of incidences of adverse reactions between the two groups 12.5% (5/40), 7.5% (3/40) was not significant.ConclusionThe clinical curative effect of Gong Yanping capsule combined with Recombinant Human Interferon α2b Vaginal Effervescent Tablets in the treatment of human papillomavirus infection is more significant than pure Gongyanping capsule treatment, it will not increase the adverse reactions of patients in a great extent, is safe and effective.