ABSTRACT
Introduction: Hepatocellular carcinoma (HCC) is the 6th most common cancer worldwide and a greater burden of this disease is born by the hepatitis B virus (HBV) endemic and resource deficient sub-Sahara Africa. This investigation was carried out to determine the pattern of hepatocellular carcinoma sub-types in north-central Nigeria. Materials and Methods: Archival formalin fixed and paraffin embedded 374 liver biopsy specimen blocks were obtained, sectioned, re-stained and examined histologically. Classification of primary liver cancers was done according to standard World Health Organisation criteria. Results: Chronic HBV infection was found in 219 (58.6%) and cirrhosis in 29 (7.8%) cases. HCC occurred in 76 (20.3%) cases with background cirrhosis in 18 (23.7%) of the HCC. The HCC subtypes found were the trabecular 54 (71.1%), acinar 10 (13.2%) and mixed trabecular and acinar 6 (7.9%), clear cell 5 (6.6%) and fibrolamellar 1 (1.3%) respectively. Conclusion: HCC is the most common histologically diagnosed primary liver cell carcinoma with the trabecular subtype as the predominant variant in Nigeria, followed by the pseudoglandular and the mixed types.
ABSTRACT
Gossypiboma is used to describe a retained cotton matrix surgical material in the body after an operation. Retained intra-abdominal surgical sponge is an uncommon surgical error. Among retained foreign bodies, a surgical gauze or sponge constitutes the most frequently encountered object because of its common usage, small size and amorphous structure. We report a case of a 32-year-old female patient who presented a left sided abdominal mass 12 years after an exploratory laparotomy. The policy of prevention coupled with use of several adjunct technologies which accounts for sponge use will help to reduce the incidence of gossypibomas.
ABSTRACT
The study was a 5 year histopathological survey of endometrial biopsies seen at the University of Ilorin Teaching Hospital ; Ilorin; North Central Nigeria from January 1st 1997 to December 31st 2001. It aimed at identifying the morphological patterns of endometrial disorders; prevalence of these disorders and the histopathological changes associated with the clinical diagnosis in Ilorin; Nigeria. Eight hundred and eighty two slides of cases of endometrial disorders recorded in the register of the Department of Pathology; University of Ilorin Teaching Hospital; Ilorin; North Central Nigeria were reviewed. Clinical data on each of the cases was retrieved from request cards. The pathological reports and clinical data were recorded noting the age; clinical history; morphological description of lesions and the histological types. The mean age of the studied group was 28 years. The commonest indication for endometrial sampling was infertility (55.3