ABSTRACT
The present study was designed to ascertain the maternal and neonatal profile and immediate outcome of extremely low birth weight (ELBW) babies at a Level III neonatal intensive care unit (NICU). Case records of ELBW inborn babies delivered between August 2000 and August 2001 were analyzed by using a preset proforma. A total of 52 ELBW babies were admitted in NICU in the relevant period, out of which 30 (57%) survived. Maternal anemia and previous pre-term (PT) delivery were the common predisposing factors for PT delivery. Mean gestational age was 27.8 weeks and mean birth weight was 831 grams. Mortality was highest in babies less than 28 weeks gestation. Neonatal hyper-bilirubinemia (78%) and HMD/RDS (65%) were the commonest morbidity. Retinopathy of Prematurity (ROP) screening could be done in 35 babies (68%), out of which 22 were found to be normal.
Subject(s)
Cause of Death , Female , Gestational Age , Humans , India/epidemiology , Infant Mortality , Infant, Newborn , Infant, Premature , Infant, Small for Gestational Age , Infant, Very Low Birth Weight , Intensive Care, Neonatal/statistics & numerical data , Male , Morbidity , Outcome and Process Assessment, Health Care , Pregnancy , Pregnancy Complications/epidemiology , Prenatal Care/statistics & numerical data , Retrospective Studies , Risk Factors , Sex Distribution , Steroids/therapeutic use , Survival RateABSTRACT
Two cases of idiopathic pulmonary hemosiderosis in children are reported. Both cases presented with a combination of acute/recurrent respiratory symptoms along with iron deficiency anemia. In one case diagnosis was delayed for 18 months after onset of symptoms. After initial stabilisation with corticosteroid therapy, both cases were put on chloroquine therapy and showed improvement. Various other forms of therapy and outcome are discussed. It is suggested that in cases with recurrent respiratory symptoms, idiopathic pulmonary hemosiderosis should also be considered after excluding infectious etiology.
Subject(s)
Adrenal Cortex Hormones/therapeutic use , Antirheumatic Agents/therapeutic use , Child , Chloroquine/therapeutic use , Female , Hemosiderosis/diagnosis , Humans , Lung Diseases/diagnosis , MaleABSTRACT
OBJECTIVE: To compare the efficacy and safety of nimesulide and paracetamol as antipyretic agents. DESIGN: Double blind, randomized clinical trial. METHODS: Hospitalized patients having fever due to a variety of infections were given either drug in a randomized manner. (Nimesulide group = 49, Paracetamol group = 50). Serial axillary temperature was recorded after drug administration and side effects monitored. RESULTS: The mean temperature after one hour of drug administration was significantly lower in nimesulide group (p < 0.05). Significantly fewer doses of nimesulide were required to bring down the temperature on the first day (p < 0.001). The mean maximum temperature recorded on second and third day was significantly lower in the nimesulide group (p < 0.05). Adverse reactions were seen in the form of epigastric pain and vomiting in one patient in Nimesulide group and three in paracetamol group. CONCLUSION: Nimesulide is more effective than paracetamol as an antipyretic agent and is safe for use in infants and children.