Non-Hodgkin lymphomas recurrence in central nervous system

A retrospective study was carried out on 32 patients with non Hodgkin lymphomas (NHL) in order to evaluate incidence rate, outcome and risk factors of central nervous system (CNS) recurrence. The results showed that: 1 patient had general manifestation and local CNS symptoms, 3 patients had CNS recurrence later on. The cumulative risk of CNS recurrence in 4 years was 19%. The CNS recurrence risk was 39% in high grade NHL, occurring usually in the first 14months, 22% in moderate grade NHL, occurring usually in the first 6 years and 7% in low grade NHL with higher degree of malignancy. In multi value analysis, NHL with high and moderate grades were independent risk factors for CNS recurrence. There are no clear evidences about role of CNS prophylaxis in patients with moderate and high grade of NHL. The survival time is 1-2 months

Special histopathological features of the uncinate processes

The study was carried out on 39 patients (18 male, 21 female, mean ages: 36.3 years old). Total of uncinate processes samples were 49. Of 39 patients, 29 patients were removed uncinate processes in one side and 10 patients were removed uncinate processes in two sides. The mean time of sinusitis was over 3 months in 32 cases (82%), 1 to 3 months in 3 cases (7.7%), and under 1 month in 4 cases (10.3%). 10 samples from uncinate processes in two side had the same histopathological lesions

The relationship of abnormal ultrasonographic findings and karyotype analysis in prenatal diagnosis

Analyse the abnormal ultrasonographic findings of 112 pregnant women who were indicated for amniocentesis at Tu Du Obstetrics and Gynecology Hospital and Hung Vuong Hospital from February 2004 to September 2005. Abnormal ultrasonographic findings were divided into two groups: one group of major abnormalities that were significant relations to chromosomal abnormalities including atrio-ventricular channel and diaphragmatic hernia; the other group of minor abnormalities that were significant relations to chromosomal abnormalities and other small ultrasonographic abnormalities, major ultrasonographic abnormalities, biochemical analyses of maternal blood and age, etc. The results showed significant relations between the number and the categories of abnormal ultrasonographic findings and chromosomal abnormalities

The relationship between clinical types of sinusitis and microscopic lesion features of uncinate processes

Study on 39 patients (18 males, 21 females, mean age: 36.3 years old) with chronic or recurrent anterior sinusitis, with or without nasal polyps, who were undergone naso-sinus endoscopies at Gia Dinh Hospital and HCMC University Medical Center from January to July 2004. Results: there was a change in microscopic imagines of uncinate processes like imagines of typical polyps although uncinate processes degeneration couldn’t be found. Polyps were common in chronic sinusitis, the rate of polyps increased along with the years of sinusitis

Reproductive factors and risk of intermediate and high grade B-cell non-Hodgkin's lymphomas

To interview 60 female patients with intermediate and high grade B-cell non-Hodgkin's lymphomas (NHL), each patient was paired with a control who is a neighbour on the age factor. Females who use oral contraceptive pills have a high risk in intermediate and high grade B-cell non-Hodgkin's lymphomas compared to controls. Among the mothers, those using anti-lactating drugs have a lower risk of NHL compared to controls. Menopausal patients have a higher NHL risk compared to women in the reproductive years, whereas menopausal women on hormone replacement therapy have a lower risk compared to controls

Sex chromosomal aneuploidy in spermatozoa of non-hodgkin lymphoma (NHL) patient before therapy

Evaluation the ratio of sex chromosomal aneuploidy in NHL patient before therapy spermatozoa by FISH (Fluorescent Insitu Hybridization) technique. Comparison semen of four NHL patients before chemotherapy or irradiation with semen of four controls in the sperm bank. No statistically significant changes in semen in patient group compared to controls. The abnormal ratio with two somatic chromosome 8-8-X or 8-8-Y and diploidy X-Y-8-8 are higher than controls. The rate of aneuploidy in sex chromosome can increase if used in assisted fecundation

The immunologic response of T-cell in large B-cell non Hodgkin lymphoma

The authors conducted a retrospective study including 72 patients with non-Hodgkin lymphoma (NHL) with large B cell, to determine the percentage of CD3+, CD4+, CD8+, and natural killer cells by flow cytometry from the biopsy specimens before treatment, and compared these results to the patients’ outcomes. Results: the increased percentage of CD4 T cell in pretreated biopsy specimens correlated significantly to the patients’ outcomes. Patients with increased CD4+ had better 5-year survival than the others. Over 20% CD4+ cell infiltrated in the pretreated biopsy specimens were independent factors of non-recurrence. The increasing of active CD4+ in large B cell NHL offered a better prognosis, and was a background in immunologic therapy of B cell NHL