Subject(s)
Acenocoumarol/administration & dosage , Adult , Female , Humans , Hyperthyroidism/blood , Prothrombin Time , Time FactorsABSTRACT
A short course of ciprofloxacin, 750 mgm b.i.d. for 7 days was found to be effective in the treatment of enteric fever in 21 hospitalized patients with S.typhi (18) and S.paratyphi A(3). Median time for fever response was 3 days. All isolates were susceptible to ciprofloxacin (MIC 0.0078-0.062 mcgm/ml). The mean serum peak and trough levels were 5.4 and 1.6 mcgm/ml respectively. Stool cultures were free of Salmonellae on follow up (11-24 weeks). Two developed recurrence of paratyphoid fever, 17 days and 4 months after therapy.
Subject(s)
Adult , Ciprofloxacin/administration & dosage , Drug Administration Schedule , Female , Humans , Male , Paratyphoid Fever/drug therapy , Recurrence , Salmonella paratyphi A/isolation & purification , Time Factors , Typhoid Fever/drug therapyABSTRACT
A case of polymyositis associated with Bancroftian filariasis in an adult male who presented with generalised painful swelling and weakness of muscles is presented. He had elevated muscle enzymes, a myopathic EMG pattern, focal vasculitis on gastrocnemius muscle biopsy and W. bancrofti in the peripheral blood. There was clinical, biochemical and histopathological evidence of resolution of the disorder and total clearance of microfilaremia with diethyl carbamazine (DEC) therapy.
Subject(s)
Acute Disease , Animals , Elephantiasis, Filarial/parasitology , Humans , Male , Middle Aged , Polymyositis/parasitology , Wuchereria bancroftiABSTRACT
An outbreak of epidemic dropsy in Andhra Pradesh was studied during August to September 1987. Thirty cases from 6 families were identified and examined. Ghee and one oil sample were found to be contaminated with the toxic compound sanguinarine. The affected families had purchased ghee from one vendor. The epidemic ended after alerting the villagers of the contaminated ghee, and stopping its further use.
Subject(s)
Alkaloids/poisoning , Benzophenanthridines , Dietary Fats/poisoning , Disease Outbreaks , Edema/epidemiology , Female , Food Contamination , Humans , India/epidemiology , Isoquinolines , MaleABSTRACT
Opportunistic infections are known to occur with increased frequency in patients with Cushing's syndrome, particularly those due to ectopic ACTH production. This report highlights the rare situation of a patient with Cushing's disease having candidal oesophagitis as one of the major presenting manifestations.
Subject(s)
Adult , Candidiasis/complications , Cushing Syndrome/complications , Esophagitis/microbiology , Humans , Male , Opportunistic Infections/complicationsABSTRACT
We report a young male with sickle cell trait who developed severe hypertension and splenic infarction soon after travel to a high altitude. Hypertension persisted for three days after a diagnostic laparotomy. His blood pressure then continued to be normal over the next one and a half years. Red cell sludging in the small vessels of the kidney possibly activated the renin angiotensin system.