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To explore influence of Xinmailong injection on cardiac function and vascular endothelial func‐tion in advanced aged patients with acute myocardial infarction (AMI) heart failure (HF).Methods : A total of 122 advanced aged AMI‐HF patients treated in our hospital from Mar 2015 to Jul 2017 were selected ,randomly and e‐qually divided into routine treatment group (received routine anti‐HF medication ) and Xinmailong group (received Xinmailong injection based on routine treatment group ) ,both groups were treated for 10d and then followed up for six months .LVEF ,wall motion score index (WMSI) ,serum levels of BNP , hsCRP , cTnI ,nitric oxide (NO) ,en‐dothelin (ET)‐1 and inner diameter of brachial artery were observed and compared between two groups before and after treatment .Results : Compared with before treatment ,there were significant rise in LVEF [routine treatment group : (35.42 ± 5.11)% vs. (44.62 ± 5.88)%;Xinmailong group : (36. 13 ± 5.64)% vs. (49.75 ± 6. 18)%] and serum NO level [routine treatmentgroup : (108. 35 ± 21.67) μmol／L vs. (129.68 ± 25. 83 ) μmol／L ; Xinmailong group : (110.26 ± 22.71) μmol／L vs. (156.82 ± 24. 19) μmol／L] ,and significant reductions in WMSI [routine treatment group : (2.49 ± 0.51) score vs. (1.45 ± 0.34) score ; Xinmailong group : (2.51 ± 0.42) score vs. (1. 12 ± 0.27) score] ,NYHA class (routine treatment group :3.19 ± 0. 44 vs. 2.65 ± 0.36 ;Xinmailong group :3. 21 ± 0.42 vs. 2.11 ± 0.28) ,serum levels of BNP [routine treatment group : (986. 72 ± 245.63 ) pg／ml vs. (764.42 ± 217.33) pg／ml ; Xinmailong group : (989.99 ± 243. 54 ) pg／ml vs. (607. 82 ± 198. 65 ) pg／ml ] , hsCRP [routine treatment group : (24.31 ± 3.82) mg／L vs. (14.52 ± 1. 69 ) mg／L ; Xinmailong group :(24.93 ± 3.74) mg／L vs. (7. 81 ± 0. 96) mg／L] ,cTnI [routine treatment group :(5.29 ± 0.43) μg／L vs. (3.01 ± 0. 27) μg／L ;Xinmailong group :(5.37 ± 0.64) μg／L vs. (1.42 ± 0.33) μg／L ] and ET‐1 [routine treatment group :(95. 67 ± 16. 32) ng／L vs. (76. 34 ± 17.82) ng／L ;Xinmailong group :(96.13 ± 17.21) ng／L vs. (57.29 ± 14. 63) ng／L] in two groups ;and LVEF and serum NO level of Xinmailong group were significantly higher than those of routine treatment group , WMSI ,NYHA class ,serum levels of BNP ,hsCRP ,cTnI and ET‐1 of Xinmailong group were significantly lower than those of routine treatment group , P＝0.001 all.Compared with before treatment ,there were significant rise in reactive hyperemia brachial diameter (Dhyperemia ) , fore brachial artery endothelium dependent diastolic‐systolic function (FMD) in Xinmailong group after treatment , and they were significantly higher than those of routine treatment group , P＜0. 05 or ＜0. 01 .Conclusion : Xinmailong injection can significantly improve cardiac function and vascular endothelial function in AMI‐HF patients ,which is worth extending .
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Objective To investigate health-related quality of life of the empty-nest elderly in Hangzhou and its influencing factors.Methods A total of 1000 empty-nest elderly were selected to participate the questionaire survey, using a stratified cluster sampling method,and the five-dimensional European quality of health scale(EQ-5D)was used to measure the health status of the empty-nest elderly. Chi square test and univariate ANOVA analysis were used to identify potential influencing factors.Results A total of 992 participants were involved in this study. The proportions of participants who had difficulties or problems in mobility,self-care,usual activities,pain/discomfort,and anxiety/depression were 16.13%,11.09%,19.76%,48.49% and 29.84% respectively. In terms of usual activities, pain/discomfort,and anxiety/depression,the proportions of empty-nest elderly who had difficulties or problems in those three dimensions were significantly higher in urban areas than in rural areas(P<0.05). The range of EQ-5D utility value was -0.11 to 0.85,with an average value of 0.75±0.13. The study showed that the elderly without chronic diseases, tending to pour out their feelings or ask for help when they were in trouble,participating activities held by political parties or communities,with lower personal incomes,and depending on children to support their life after retirement were more likely to have higher EQ-5D utility values(all P<0.01).Conclusion The health-related quality of life of empty-nest elderly in Hangzhou is at a low level,and is influenced by several soci-demographic factors. Encouraging the elderly to ask for help,improving the management of chronic diseases and providing more social supports could improve the health-related quality of life of the elderly.
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Objective To learn the pension willingness and influencing factors of empty-nest elderly in Hangzhou City. Methods A total of 1000 empty-nest elderly in Hangzhou, taking a formal hosusehold registration, living≥1 year, age≥ 65 years old, were selected from two urban districts and three suburbs by multi-stage simple random sampling, and were surveyed with questionnaires. The data was analyzed by logistic regression model to study the influencing factors of pension willingness. Results A total of 992 valid questionnaires were collected and the effective rate was 99.20%. There were 407 (41.03%) , 365 (36.79%) , 208 (20.97%) and 12 (1.21%) people in the 992 empty-nest elderly, choosing their children's support, social pension insurance, personal pension and other old-age methods. Multivariate logistic regression analysis showed that, the empty-nest elderly who worried about pension costs (OR=3.007, 95%CI:1.751-5.155), and the greatest wish was physical health (OR=4.404, 95%CI:1.461-13.276), family harmony (OR=7.724, 95% CI: 2.158-27.646), children work smoothly (OR=4.811, 95%CI: 1.203-19.246) . The lower health score (OR=0.982, 95% CI: 0.965-0.999), choosing their children's support as their pension willingness were relatively high, and the empty-nest elderly who worried about pension costs (OR=2.058, 95%CI: 1.267-3.344), the original occupation for the staff (OR=2.353, 95% CI: 1.091-5.078) , city household registration (OR=0.546, 95% CI:0.349-0.856) . The lower the health score (OR=0.979, 95%CI: 0.966-0.993) choose social pension insurance as their pension willingness would be relatively high pension. Conclusion The influencing factors of the pension willingness of the empty-nest elderly were worried about pension costs, the greatest wish, and health status, urban and rural household registration.
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<p><b>OBJECTIVE</b>To assess the test-retest reliability and criterion validity of the Simplified Chinese-character version of the International Physical Activity Questionnaire Long form (IPAQ-L) in urban community-dwelling adults in Hanghzou, China.</p><p><b>METHODS</b>A total of 158 eligible participants aged 25-59 years from 6 neighbourhoods in two central districts of Hangzhou completed the IPAQ-L questionnaire twice within a 7-day interval. Half of the subjects wore pedometers during the first 7 days. Test-retest reliability was examined by comparing the first (Day 1) and the second (Day 9) survey of IPAQ-L. Criterion validity was assessed by comparing IPAQ-L with pedometer data.</p><p><b>RESULTS</b>Modest to good test-retest reliability was found with intraclass correlation coefficients of 0.67 for total PA, 0.37 to 0.73 for specific dimensions, and 0.56 to 0.71 for different intensities of PA. Total PA measured by IPAQ-L was moderately correlated with exercise levels (partial r = 0.27, P = 0.020) and walking distance (partial r = 0.31, P = 0.007), which were measured by a pedometer, after adjusting for gender, age, educational attainment and employment status.</p><p><b>CONCLUSION</b>Our results indicate that the IPAQ-L is a reliable and validated measure for assessing physical activity levels in this population and possibly the adult population in other mainland Chinese cities.</p>
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Adult , Female , Humans , Male , Middle Aged , China , Cross-Sectional Studies , Exercise , Reproducibility of Results , Surveys and Questionnaires , Reference Standards , Urban PopulationABSTRACT
Objective To know the status of nutrition education of community medical staff and analyze its association with nutrition intervention consciousness and behaviors.Methods Three representative districts including Xiacheng,Gongshu and Westlake were selected and 846 community medical staff was involved in this study.Questionnaire investigation was applied to collect the information from mainly three aspects including training,consciousness and practice.Logistic stepwise regression analysis and Cochran -Mantel -Haenszel test were used.Results Most of the community medical staff was female (78.49%).78.95% of the staff had received the training of nutrition knowledge and its main influencing factor was working time.The Association was observed between the nutrition training and the preparation of nutrition consultation. The more training received,the higher self -assessment would be (P <0.05 ).Meanwhile,as the types of training increased,the awareness and attitude of medical staff was improved remarkably,such as knowing risks of unhealthy dietary,asking the dietary habit of the patients routinely,and advising patients to establish a good dietary habit to their children (all P <0.05 ).Nutrition training also had a positive association with nutrition intervention behavior ,such as implementing more measurement of blood pressure, weight, and blood cholesterol for community outpatients, communicating with them in the importance of balanced diet and proper nutrition,and giving weight loss suggestion to obese patients (all P <0.05).Conclusion Training on nutrition knowledge and intervention skills of community medical staff should be emphasized and reinforced in the future,in order to promote the effect on chronic diseases prevention of community -based intervention strategies.
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Objective To understand the epidemic status of metabolic syndrome among Hangzhou enterprise workers and to describe the distribution of metabolic -related subtypes.Methods 2 066 employees were recruited from 1 2 enterprises and institutions in three districts of Hangzhou city.A standardized self-administered questionnaire was conducted and metabolic-related anthropometric measurements were taken.Metabolic syndrome was defined according to the International Diabetes Federation (IDF)(2005 standards).Results Prevalence of metabolic syndrome in Hangzhou enterprise workers was 1 0.72%,the standardized rate was 1 3.48%;levels of waist circumference,blood pressure,blood FPGcose, triglycerides,high-density lipoprotein and prevalence of metabolic syndrome of high age group were significantly higher than the low age group(P<0.05 ).Levels of blood pressure,blood FPGcose,triglycerides,high-density lipoprotein of males were significantly higher than females (P <0.05 ).Levels of blood FPGcose of low -educated group were significantly higher than that in high-educated group (P<0.05 ),while triglycerides level was lower than high-educated group (P<0.05 ).In subtypes of metabolic syndrome,the prevalence of TG plus HDL,BP plus HDL,BP TG plus HDL and BP FPG TG plus HDL were higher than 1 0.00%.Conclusion Prevalence of metabolic syndrome in Hangzhou enterprise workers is high;male and older-group has a higher risk;TG plus HDL may be the main metabolic syndrome subtype.
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Objective To investigate the relations between training and both the attitude and practice on smoking control among community medical staff members in Hangzhou,Zhejiang province.Methods Three representative districts including Xiacheng,Gongshu and Westlake were chosen from Hangzhou city.Questionnaire survey was applied to collect information from the related community medical staff members.The survey mainly contained three aspects:knowledge,attitude and practice regarding smoking control involved in the community medical activities.Availability and application of the resources on smoking cessation were also studied.Logistic regression analysis was applied to explore the factors associated with the smoking control training programs.Differences of rates between groups were assessed with chi-square statistics.Wilcoxon rank sum test was used to study the relationships among knowledge,attitude and practice related to smoking control programs,targeted to the community medical staff members.Results Eight hundred forty-six community medical workers were involved.Sixty-five percent of the community medical staff members had learned related knowledge on smoking control.Proportion of the community medical staff who had taken lessons on smoking control with 3-10 working years was 1.77 times more than the ones with experience less than two years (OR=1.77,95％CI:1.25-2.51).Eighty-eight point seven percent of the medical staff who had received smoking control training programs were identified with the consciousness that they should advise the patients to quit smoking,comparing to the proportion 81.60％ (Z=-2.87,P=0.00) in the control group.In terms of the practice regarding smoking control,data showed that 21.62％ of the medical staff who had received smoking control training programs would provide ‘how to quit smoking' to more than 90％ of the smoking patients,while the proportion in the control group was 10.65％ (Z=-5.68,P=0.00).The use of drugs,traditional Chinese medicine therapy and the smoking cessation hotline rate were all less than 30％.Conclusion The training programs being used on smoking control seemed useful in improving the consciousness and practice towards the smoking control programs during their medical activities among the community medical staff members.
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Objective To investigate the effect of workplace intervention programs related with health-promoting lifestyles among community medical staff members in the communities of Hangzhou city.Methods Three representative districts including Xiacheng,Gongshu and Westlake were chosen and all the community medical staff was involved in the study.Questionnaire survey was applied to collect the information from all the community medical staff.Three aspects including 1,environmental support and policies on healthy lifestyles 2,lectures and activities related to healthpromoting programs provided,and 3,peer effect on health promotion,were studied.Chi square test and logistic stepwise regression analysis were applied.Results Intervention strategies on smoking,diet and physical exercises were analyzed respectively.It was indicated that none of the lectures,regulations or individual counseling regarding smoking cessation was associated with the decrease of smoking behavior.Medical staff that taking part in the lectures on balanced diet showed higher frequencies of vegetable/fruit intake,with the frequencies of vegetables/fruits consumption on 4 or more days/per week appeared 1.74 times more than that in the control group.As for the physical exercise intervention was concerned,the peer effect was found to be obvious.Medical staff that taking exercise with colleagues tended to do more exercises with frequency in taking moderate or high intensity exercises 5 or more days/per week as 1.62 times than that of the control group.Data also indicated that regardless of intervention programs on diet or on physical activities,the combination effect could statistically improve the healthy behavior on diet or physical exercise.Conclusion Intervention programs on both balanced diet and physical exercises were preliminarily found to be associated with enhanced health promotion behavior for workplace health promotion strategies but need to be verified through further intervention studies of the same sort.
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Objective To explore the fruit and vegetable (FV) consumption and related influencing factors among urban junior students in Hangzhou.Methods In a cross-sectional study,a self-administered questionnaire was used to assess the frequency and amount of FV consumption as well as related socio-demographic characteristics.Logistic regression method was applied to study other factors related to the amount of vegetables consumption ≥ 21 servings and fruit comsumption ≥14 servings per week.Results Among 3724 junior students included in this study,54.7％ of them consumed FV daily,23.6％ consumed vegetables ≥21 servings and fruit ≥14 servings per week (equaled to vegetables ≥3 servings and fruit ≥2 servings every day).The level of FV intake was high in girls,mother with higher education,and higher family socioeconomic status (SES).After controlling 5 socio-demographic factors,data on the consumption of daily vegetables ≥21 servings and fruit ≥ 14 servings weekly,were positively associated with daily physical activity (PA) ≥60 min (OR=1.667,95％CI:1.216-2.203),encouragement on FV intake daily by family (OR=1.881,95％ CI:1.498-2.363),positive familial attitude on the daily intake of FV (OR=1.275,95％ CI:1.025-1.586),preparation FV 3-6 days per week (OR=1.691,95％CI:1.310-2.183) or daily (OR=2.944,95％ CI:2.348-3.690),family consumption of FV with children/3-6 days per week (OR=1.392,95％ CI:1.056-1.835) or on the daily base (OR=2.817,95％ CI:2.217-3.580),breakfast usually made at home (OR=1.364,95％ CI:1.158-1.607),offering FV course atschool last year (OR=1.238,95％CI:1.035-1.480) and awareness on the benefit of FV (OR =3.150,95％ CI:1.121-8.856) etc.respectively.Conclusion Socio-demographic characteristics,daily PA,dietary pattern at home,education and awareness on the benefits of FV on health etc.were all related to the FV intake among junior students in Hangzhou.
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Objective To evaluate the short-term impact of comprehensive communitybased intervention on physical activity (PA) of adults living in the three urban communities of Hangzhou city.Methods Within the framework of Community Interventions for Health (CIH) Program,a community trial was conducted in two urban areas (Xiacheng district and Gongshu district) and an urban area (Xihu district) as control,by a parallel comparison and random grouping based quasi-experimental design.Two independent questionnaire-based surveys of cross-sectional samples in the intervention and comparison areas were used to assess the short-term impact of the intervention program.Results A total of 2016 adults at baseline and 2016 adults at follow-up stages,completed the survey,including 1016 adults from the intervention areas and 1000 from the comparison area.Over the two-year intervention period,the cognitive level on benefits of physical activity in the intervention areas were trending downward.The changes observed in the comparison area did not show statistical significance.Intervention areas showed a statistically significant increase (1204 vs.1386,P=0.023) in the level of physical activity (metabolic equivalent,MET-minutes/week) compared with the comparison area (918 vs.924,P=0.201).And results remained the same after eliminating the possible effects of age factor.Conclusion After a two-year intervention,beneficial changes were noted in the intervention areas with respect to the level of physical activity.A community-based intervention program on physical activity seemed feasible and effective in the urban areas of Hangzhou.
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Objective To explore the rate on completion of the recommended physical activities and its correlates among junior students in 3 urban districts of Hangzhou.Methods Describing the range on completion of the recommended physical activities and analyze its related demographic,cognitive and environmental factors with logistic regression model among 3867 juniors students.Results 7.7％ of the junior students could achieve the recommended physical activities requirements.The proportions of students who were aware of the recommendation on physical activity programs showed as 31.0％.59.2％ of juniors students had physical education (PE) classes in 3 days or more within 1 week.Factors as being male (OR=2.94),believing that adolescents should take part in at least 60 minutes' physical activities a day(OR=4.95),having PE classes in 3 days or more within 1 week (OR=1.44),with family encouragement on physical activities (OR=--1.06) and taking part in physical activities together (OR=1.14),perceiving the idea that they had enough sports equipment at home (OR=1.22) and had convenient access to sports facilities around the residential areas (OR=1.09),and perceiving the idea that it was not safe to walk or jog around the residential area (OR=i.11 ) etc.had statistically significant correlations with achieving the recommended physical activities among juniors students.Conclusion Demographic,cognitive and environmental factors had some influence on the completion of recommended physical activity program among junior students.
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Objective To study the status of physical activity (PA) and sedentary behaviors and relevant knowledge to it among junior students.Methods In a cross-sectional study,a selfadministered questionnaire was used to assess the PA,sedentary behaviors and relevant knowledge on 4549 eligible urban junior students.Results Among the 4549 junior students,only 7.50％ engaged in ≥60 minutes of PA,per day.Those junior students spending 2 hours on weekdays,3 hours on weekends in doing homework and those spending ≥30 min on weekdays,2 hours on weekends in doing other sedentary activities,accounted for the highest proportion of the subjects respectively.The awareness rate of spending at least 60 minutes each day on PA to stay fit and healthy was 24.63％.Differences in gender and grade at school were significantly on ‘understanding of health benefits regarding PA' (P＜0.05).Conclusion Urban junior students were lack of awareness and appropriate behavior on physical activities so the related intervention should be taken actively to improve the current situation among the adolescents at school.
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Objective To study the prevalence rates of knowledge,attitudes and use of the nutrition labeling and related influential factors in Hangzhou supermarket consumers.Methods Using a self-developed survey questionnaire,randomly selected customers were conducted a face-toface interview program in a large supermarket of Hangzhou city.Results 586 people were interviewed,including 202 males and 384 females,with the mean age as 41.6±17.23 years.The Facts Labels'were as follows:dietary fiber(71.84%),fat(70.99%),calcium(60.75%),salt (58.36%),energy(50.85%)and sugar(39.42%).The support rates of the three attitudes indicators were"support marking the Nutrition Facts Label"(90.44%)."support marking the nutrition claims"(87.03%)and"want to know more relative knowledge"(77.13%).There were 58.36% and 80.03%first-time buyers who would read the Nutrition Facts Food Labels and the Nutrition Claims.Through logistic model analysis,male,youth,low-educated people were found to be the risk factors related to the nutrition label reading behavior.Conclusion The capacity of the reading,understanding and correct application of nutrition labeling among consumers was not satisfactory.Improvement on the readability and the authority of nutrition labeling and the development of the national nutrition knowledge and health education programs were in urgent needs.
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To introduce the application of vignettes in the survey on health condition,we took the Hangzhou health survey as an example. We tried to find the respondents' health judgment standard by using vignettes first and discovered the population' s demographic characteristics as sex,age, years of schooling and income etc. could influence the self-reported health condition on the response category cut-points. Then the cut-points were corrected through hierarchical ordered probit model in order to reflect the respondents' self-reported health condition based on the same standard,making the result suitable for comparison. Data from our research discovered that the level of health condition of females was lower than that of males among the residents living in Hangzhou and the higher income they received, the better health condition they had. Thus, the health vignettes seemed very essential in the survey on health condition.
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Objective To study the feasibility of a simple random sampling on surveys at the community level and to evaluate the quality of samples under survey.Methods A simple random sample of households was taken,based on the electronic listings of community households from Gongshu and Xiacheng districts of Hangzhou city.One of the adults aged 18 to 64 years in the sampled households was identified with KISH method to finish a questionnaire survey.More than 500 people from the sample size was required in each district.Results Of 950 sampled households in Xiacheng district,511 (53.8%) finished the survey while 506 (36.7%) out of the 1380 sampled households in Gongshu district did.The proportions of non-response due to the following reasons as:none with eligible age in the households,relocation of the original household,mass relocation of the community,and errors in the household listings etc.were 38.3% and 43.5% respectively,in the two districts.Proportions attributed to non-response and refusal to response of sampled household or individual were 8.0% and 19.9% respectively.No statistical significant differences in age and gender were found between the surveyed samples and the population in the sampled households,or in gender between the populations in the sampled households and in Hangzhou city.However,the population in the sampled households showed a more aging population structure than the population in Hangzhou city.Conclusion In a geographically limited area,using a simple random sampling method to do the survey is feasible,based on the electronic listings of household.Enough time spent during the household visit guarantees the interviewers to get a representative sample of the sampling frame.There is an urgent need for the timeliness,completeness and accuracy of electronic household listings to be improved.
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Objective To explore the relationship bet-ween air pollution and acute onset of cerebral hemorrhage in Hangzhou.Methods Time-stratified case-crossover study was used to analyze the effect of aerosol optical depth(AOD),PM10,SO2 and NO2 on the acute onset of cerebral hemorrhage.Conditional logistic regression was used to estimate the odds ratios(Ors) and their 95% confidence intervals(Cis) in relation to an increase of one unit of AOD and 10 μg/m3 of air pollutants.Results After adjusted temperature and relative humidity,the Ors of acute onset of cerebral hemorrhage by a unit increase in AOD at a 2 day-lag were 1.727(95%CI:1.103-2.703)in first half year and 2.412 (95%CI:1.230-4.733) at a 2 day-lag in spring.For a 10 μg/m3 increase in SO2,the Ors were 1.119(95% CI:1.019-1.229),1.230(95%CI:1.092-1.386),1.254(95%CI:1.076-1.460) in the whole year(2 day-lag),in first half year(2 day-lag) and in spring(2 day-lag),respectively.NO2 exposure in first half year(2 day-lag) was associated with cerebral hemorrhage,with OR as 0.841(95% CI:0.734-0.964).However,there were no statistical significances for AOD,SO2,NO2 in the rest time-periods(P>0.05).Additionally,no association was found between PM10 and the acute onset of cerebral hemorrhage in any time-periods(P>0.05).Conclusion Our data showed that there was association between air pollution and the acute onset of cerebral hemorrhage,especially in spring and in the first half of the year.
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the migrant workers' families.
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Objective To investigate the short-term effect of particulate matter in air on the mortality of stroke. Methods Using time-stratified case-crossover study design,an association was examined between stroke mortality and particulate matter with aerodynamic diameter of ＜10μm(PM10) of 2002- 2004 in Hangzhou city.Meanwhile,the acute health effect of other gaseous pollutants (sulfur dioxide,SO2 and nitrogen dioxide,NO2) was also analyzed.Results A total of 9906 deaths of stroke were included.The crude stroke mortality was 83.54 per 100 000.After being adjusted for meteorological factors,when an increase of 10 μg/m3 in PM10,SO2 and NO2 in three days was noticed,it appeared that the increases of mortality of stroke were 0.56%(95%CI:0.14%-0.99%),1.62%(95%CI:0.26%-3.01%) and 2.07%( 95%CI:0.54%-3.62%) respectively.There was no distinct association in multipollutant models.In sensitivity analysis,the associations were found in all single-pollutant models but not statistically significant in multi-pollutant models after replacing the missing values.Conclusion It is suggested that the short-term elevation in PM10 as well as SO2 and NO2 daily concentrations were related to the increase of stroke mortality in Hangzhou city.