ABSTRACT
Abstract INTRODUCTION: Vaccination against varicella-zoster virus (VZV) has been effective and safe in countries that routinely administer the vaccine. Brazil began universal VZV vaccination in 2013. This study aimed to identify VZV genotypes present in Manaus, Brazil prior to widespread immunization. METHODS: Vesicular lesions or cerebral-spinal-fluid samples were collected from patients diagnosed with VZV, herpes zoster, or meningitis/encephalitis. DNA was extracted, amplified, and sequenced. RESULTS: Half the isolates were clade-5 viruses and the remaining were divided between the European clades 1 and 3. CONCLUSIONS: This study provides insights into the circulating VZV genotypes in Manaus prior to widespread vaccination.
Subject(s)
Humans , Male , Female , Child, Preschool , Child , Adolescent , Adult , Aged , Herpesvirus 3, Human/genetics , Varicella Zoster Virus Infection/virology , Herpesvirus 3, Human/isolation & purification , Genotype , Middle AgedABSTRACT
O hematoma espontâneo do músculo reto abdominal é uma condição incomum, causado pela concentração de sangue emsua própria bainha muscular, sem associação com traumas, mas pelo rompimento dos vasos epigástricos ou por lesão da própria musculatura. O presente trabalho relata o caso de uma idosa de 75 anos que apresentou, após crises de tosse, intensa dor abdominal e equimose periumbilical e em flancos, simulando abdome agudo, caracterizado como hematoma espontâneo do músculo reto abdominal após exames de imagem. A paciente foi submetida a tratamento conservador, mas, no 20° dia após o quadro agudo, evoluiu com abscesso local, sendo tratada com drenagens e antibióticos. Ressalta-se a importância do reconhecimento do quadro na prática clínica, pois sua semelhança com outras condições abdominais agudas pode levar a intervenções cirúrgicas desnecessárias...
Spontaneous rectus sheath hematoma is a rare situation, caused by the accumulation of blood inside the rectus abdominal muscle sheath, not associated with trauma, because of rupture of epigastric vessels or muscle lesion. This paper reports the case ofa 75-year old woman, who presented severe abdominal pain and ecchymosis, identified as spontaneous rectus sheath hematoma after imaging. She was treated conservatively, but an abscess was drained and used antibiotics on the 20th day after the beginning of pain, finally resolving the case. This report reinforces the need for recognizing this situation in clinical practice, because it is similar to other acute abdominal conditions, and it could lead to an unnecessary surgery...