Importance of E histolytica antigen in serodiagnosis and follow-up of patients with amoebic liver abscess

A community - based study was conducted on 200 apparently healthy individuals randomly chosen from rural areas. They were examined clinically, sonographically and parasitologically for E. histolytica cysts and by ELISA for circulating amebic antigen. They were negative for antigenemia at 1/16, which was considered the diagnostic titer of amebic hepatitis. A hospital - based study was carried out on 27 patients suffering from amebic liver abscess [ALA]. Circulating amebic antigen was detected in 66.66% of them before treatment, which decreased to 14.82% 2 months after treatment. There was no significant association between the diameter of the abscess and the level of circulating amebic antigen. It was concluded that the circulating amebic antigen may be useful for the diagnosis and follow up of amebic liver abscess patients

Importance of E hislolytica antigen in serodiagnosis and follow-up of patients with amoebic liver abscess

This study was composed of two sections: A community based study and a hospital based study. The community based study was conducted on 200 apparently healthy individuals who were chosen randomly from rural areas. They were examined clinically, sonographically and their stools were analyzed microscopically for E. histolytica cysts. They were examined serologically by ELISA test for the circulating amoebic antigen to determine the normal titer of antigenemia among healthy individuals and cyst passers. It was found that all of them were negative for antigenemia at 1/16 which was considered the diagnostic titer of amoebic hepatitis. The study was carried on 27 patients suffering from amoebic liver abscess [ALA] to detect the role of circulating amoebic antigen in the diagnosis and follow up of these cases. Circulating amoebic antigen was detected in 66.66% of patients with ALA before therapy which was decreased significantly to 14.82% two months after therapy. There was no significant association between the diameter of the abscess and the titer of the circulating amoebic antigen in their sera

Toxoplasma lgG and lgM antibodies, a case control study

This study includes 62 eases of spontaneous abortions and 75 cross matched non pregnant multiparous women as controls. Micro - ELISA test was done to assess the extent of infection by Toxoplasma IgM and IgM antibodies. Out of 62 aborting women, 26 gave positive antitoxoplasma IgG antibodies [43, 56%] more than 45 Eu/ml and 28 gave positive antitoxoplasma IgM antibodies more than 40 Eu/ml without statistical significant difference. There was a significant difference between aborting women and the controls as regards IgG and IgM antibodies. Regarding antitoxoplasma IgG antibodies, there was a statistical significant difference between those with no previous abortions or 1 - 2 abortions versus those with 3 and more abortions. The infection was more among aborting women in rural than urban area. Also it is evident than risk factors contributing to the tranmission of disease among aborting women indicate unhygienic measures awareness about the mode of transmission of toxoplasma infection. It is recommended that women should be protected from toxoplasma infection and routinely examined for toxoplasma antibodies before marriage or pregnancy

relation between ABO blood groups, HLA typing and giardiasis in children

A total of 455 children were chosen randomly and surveyed for giardiasis by stool examination using several techniques. A case control study design was adopted, where 91 cases of giardiasis [symptomatic and asymptomatic] and 101 children giardiasis free were examined. ABO blood groups and HLA typing were investigated. It was concluded that blood group A was more susceptible to giardiasis especially asymptomatic form, while blood group B was less susceptible to giardiasis. On the other hand, there was no association between AB or O and giardiasis. But, there was a strong association between HLA A10, A11, B5, B7 and B17 phenotypes and symptomatic giardiasis and an association as well between HLA B7, B17, Bw14 and Bw40 and asymptomatic giardiasis