ABSTRACT
Background: Metabolic syndrome is a group of abnormal laboratory and physical findings, such as dyslipidemia, hypertension, glucose intolerance, proinflammatory state, and prothrombotic state that results in a patient having significantly higher risk for atherosclerosis, cardiovascular disease, and overall mortality. There are slight differences between institutions in defining metabolic syndrome across the world. To achieve adequate management and treatment and decrease the risk of subsequent diseases, proper identification of symptomatic patients with metabolic syndrome is necessary
Aim: In this review, we aimed to study the pathophysiology behind the development of metabolic syndrome, and also to explore the approach to its management
Materials and Methods: We conducted this review using a comprehensive search of MEDLINE, PubMed, and EMBASE, January 2001, through February 2017. The following search terms were used: metabolic syndrome, pro-thrombotic state, pro-inflammatory state, diabetes mellitus, insulin resistance, obesity and cardiovascular mortality
Results: The major aspects of treatment include weight reduction by diet, medication, as well as bariatric surgery [in some cases], and managing hyperglycemia and insulin resistance with diet and medication
Conclusion: The most important intervention in managing patients with metabolic syndrome is lifestyle modification with improved diet and exercise. To achieve adequate treatment and decrease the risk of adverse outcomes, proper identification of symptomatic patients with metabolic syndrome is necessary
ABSTRACT
Bile duct stones [BDSs] may happen in up to 4%-15% of all patients for whom cholecystectomy is performed. Patients giving CBDS have manifestations including: biliary colic, jaundice, cholangitis, pancreatitis or might be asymptomatic. It is critical to recognize essential and auxiliary stones, in light of the fact that the treatment approach shifts. Stones found some time recently, amid, and after cholecystectomy had likewise contrasting medicines. Distinctive strategies have been utilized for the treatment of CBDS yet the appropriate treatment relies on upon conditions, for example, quiet' fulfilment, number and size of stones, and the specialists involvement in laparoscopy. Endoscopic retrograde cholangiopancreatography with or without endoscopic biliary sphincterotomy, laparoscopic CBD investigation [transcystic or transcholedochal], or laparotomy with CBD investigation [by T-tube, C-tube inclusion, or essential conclusion] are the most regularly utilized strategies overseeing CBDS [Common bile duct stones]. We will survey the pathophysiology of bile duct stones, finding, and distinctive procedures of treatment with particular concentrate on the different surgical modalities