1.
Blood Research
;
: 61-64, 2014.
Article
in English
| WPRIM
| ID: wpr-228926
ABSTRACT
Oxaliplatin is a platinum compound used in patients with gastrointestinal malignancies. It is known to evoke a drug-induced immune-mediated thrombocytopenia, which has not been reported in Korea. We describe a 53-year-old man who developed oxaliplatin-induced immune-mediated thrombocytopenia during chemotherapy for colon cancer. Oxaliplatin-dependent IgG platelet antibodies were detected in his serum on flow cytometry. He was treated with immunoglobulin and corticosteroids without any complications. Physicians should consider oxaliplatin-induced immune-mediated thrombocytopenia, when a sudden, isolated thrombocytopenia develops during chemotherapy with oxaliplatin.
Subject(s)
Humans , Middle Aged , Adrenal Cortex Hormones , Antibodies , Blood Platelets , Colonic Neoplasms , Drug Therapy , Flow Cytometry , Immunoglobulin G , Immunoglobulins , Korea , Platinum , Thrombocytopenia
2.
Korean Journal of Blood Transfusion
;
: 239-245, 1993.
Article
in Korean
| WPRIM
| ID: wpr-128812
3.
Korean Journal of Blood Transfusion
;
: 239-245, 1993.
Article
in Korean
| WPRIM
| ID: wpr-128797