ABSTRACT
The analgesic activity of dried roots extracts of Reidia floribunda was studied after the intraperitoneal injection in mice using acetic acid-induced writhing method. After treatment, ethanolic extract produced greater analgesia with maximum analgesic activity than petroleum ether and benzene extracts. Extracts were tested against some gram negative and gram positive micro-organisms by Disc Diffusion method. Ethanolic and chloroform extracts were more effective than petroleum ether extract
Subject(s)
Animals, Laboratory , Male , Female , Plant Extracts , Analgesics , Anti-Infective Agents , Mice , Treatment Outcome , Microbial Sensitivity TestsABSTRACT
The analgesic activity of the dried leaves' extract of Acalypha indica was studied after oral administration in mice using the acetic acid induced writhing method. The analgesic activity of the various extracts like petroleum ether, chloroform and methanol was studied. There was significant analgesic activity of the extracts of chloroform and methanol whereas petroleum ether's extract does not possess analgesic activity. The anti-inflammatory effect was studied by using histamine included paw oedema for different extracts. All the three extracts showed highly significant effect for this activity. Extracts tested against some gram negative and gram positive micro-organisms by two-fold serial dilution method were found to be devoid of anti-bacterial activity
Subject(s)
Animals, Laboratory , Plant Extracts , Plant Leaves , Anti-Inflammatory Agents, Non-Steroidal , Analgesics , Anti-Infective Agents , RatsABSTRACT
Aqueous neem extract, prepared from the neem [Azadirachta indica] bark, was tested against the strain of bacteria Proteus vulgaris and fungi Candida albicans, to examine its efficacy as an antimicrobial activity. The growth inhibitory property of the aqueous extract has been noticed and recorded in terms of zone of inhibition measured in the 24 hrs growth culture using disc plate techniques
Subject(s)
Proteus vulgaris/drug effects , Candida albicans/drug effects , Bacteria/drug effects , Antifungal AgentsABSTRACT
Effect of formulated cream of leaf volatile oil of Atalantia monophylla Correa. for wound healing and antimicrobial activity [bacteria and fungi] were evaluated. The volatile oil was distilled from leaves by using hydrodistillation method. The 2% and 5% cream was prepared by using base [stearic acid, potassium hydroxide, cetostearyl alcohol, liquid paraffin, petroleum jelly, propyl paraben sodium, methyl paraben sodium and glycerin]. The cream showed very good wound healing activity by excision wound method in rats compared to that of standard drug Nitrofurazone. The antimicrobial activity of 2% femulated cream was also carried out by standard cup plate technique using Ciprofloxacin and Nystatin as standard drugs for bacteria and fungi respectively