High copper and low blood zinc are biochemical trait markers of depression

Study was designed to evaluate the serum status of trace elements in depressive patients, which will be handy for diagnosis and prompt treatment of depression. Study was conducted at the Biochemistry Department of B.M.S.I, J.M.P.C, Karachi since July 2004 to Feb. 2005. Diagnosed depressive cases were taken with the collaboration of Psychiatric department J.P.M.C Karachi, Pakistan. Total of 30 depressive patients among them 18 were males and twelve were females with mean age of 37.9 years along with 20 controls participated in the study. Copper and zinc in the blood sample of the depressive patients and normal controls were measured. Significant elevated blood levels [p<0.05] of copper and significantly decreased levels of Zinc [p<0.05] in the depressive patient as compared to control were found. Excess copper and low blood zinc levels are biochemical trait markers for early diagnosis of depression

Low serum zinc and higher risk of CA prostate in local population study

Study was designed to evaluate the Serum status of Zinc in CA Prostate patients and then match to PSA levels to obtain any significant correlation of Serum Zinc values the risk of CA prostate. Study was conducted at the Biochemistry Department of B.M.S.I, JMPC. Diagnosed CA Prostate cases were selected with the collaboration of Urology and Radiotherapy Department, J.P.M.C, Karachi since June 2006 to July 2007. Total thirty five [35] diagnosed CA Prostate patients and thirty five controls were participated in the study. Zinc and PSA were measured in the blood samples of prostate patients. Significant low zinc blood levels [p<0.05] and significantly high levels of PSA [p<0.05] in the CA Prostate patients as compared to control were found. Serum zinc was estimated in prostate cancer patients, we found significantly decreased levels of zinc [p<0.005] in cancer patients when compared to control group