Cervical cytopathological changes with the use of oral contraceptives

Cytological examinations are carried on 526 patients who are classified into two groups: Control group, including 164 cases with clinically free cervix and 115 cases with clinical cervical erosion and test group included 134 cases using oral contraceptive pills with clinical cervical erosions. It was found that there is no significant difference in inflammatory smears in both groups. The incidence of squamous metaplasia was higher in pill users with clinically free cervix, but not different from the control group with clinical cervical erosion. Squamous metaplasia was higher in pill users with clinical cervical erosion than the whole groups. Dyskariotic changes were higher in pill users with clinical cervical erosion than the control group with clinically free cervix, but not different from the other groups. Only one case of carcinoma in situ was detected among pill users with clinical cervical erosion

Amniotic fluid creatinine in normal and abnormal pregnancy

Creatinine, an important constituent of the amniotic fluid that was recently used in clinical obstetrics to assess the foetal maturity in uterois it was found to increase progressively as pregnancy advances. To study the effect of hypertensive toxaemia of pregnancy on the amniotic fluid creatinine, 135 pregnant patients in their last trimester were included in this work: 35 cases of normal pregnancy and 100 cases of hypertensive toxaemia. All have had abdominal amniocentesis, and the creatinine content was estimated by the Coleman Junior spectrophotometer using the alkaline picrate method of Bonsnes and Tausky