Immunological study on cigarette smokers Part I effect of smoking on the serum immunoglobulin levels

Twenty asymptomatic apparently healthy adult male smokers, 20 to 60 of age, ranging from mild to heavy smokers were compared with 10 apparently healthy non-smokers of the same sex and age range as regards serum immunoglobulin levels. The results obtained revealed a significant increase, in serum IgE level in smokers compared to non-smokers irrespective of the extent of smoking. Serum IgG and IgM levels declined with smoking and this decline was statistically significant in heavy smokers for IgG and in moderate and heavy smokers as well as in smokers in general for IgM. Serum IgA ana IgD levels showed no significant changes

Streptococcal infection of chronic maxillary sinusitis: an immunological study using the skin window test

Thirty patients with chronic maxillary sinusitis caused by haemolytic streptococci and 10 normal subjects were included in this study. Their cell mediated immunity was assessed by the skin window technique. Own streptococcal antigen, foreign streptococcal antigen and saline as control were used. The patients showed negligible lymphoblastic transformation when using own antigen, and better response when using foreign streptococcal antigen. The patients showed lower response to foreign antigen compared to the controls. So patients with chronic maxillary sinusitis have depressed cell mediated immunity