ABSTRACT
This study was carried out on 1137 healthy male and female Saudis of different age groups to establish normal reference ranges for immunoglobulins [IgG, IgM and IgA]. The ranges were established using mean +/- 2SD and 2.5th to 97.5th percentiles. Immunoglobulin levels were estimated using rate nephelometry and a close correlation was found between the results obtained by rate nephelometry and radial immunodiffusion. A positive correlation was obtained between levels of IgG, IgM and IgA with age. Furthermore, significant differences related to sex were encountered. Both IgG and IgM levels were significantly higher in the females compared to the male population. However, IgA did not show any difference. Comparison of the results, with those reported in the literature showed several marked differences. In this paper the normal reference ranges for IgG, IgA and IgM in healthy male and female Saudis are presented and the results are compared with those reported in literature
Subject(s)
Immunoglobulin M , Immunoglobulin A , Nephelometry and TurbidimetryABSTRACT
This study was conducted on 543 males and 603 females in order to establish the normal reference value for plasma transferrin using rate nephelometry. A significant difference was found in the mean values and ranges in the male and female populations and a positive correlation was demonstrated between the transferrin level and age. The results showed a normal transferrin distribution. It was found that for males the normal reference value for transferrin was 310 +/- 125 mg/dl while for the females the reference value was 335 +/- 170 mg/dl. Among the children [= 10 years] a plasma transferrin range of 290 +/- 100 mg/dl is suggested as a normal reference range