Analgesic, anti-inflammatory and diuretic activities of Cicer arietinum L.

Analgesic, anti-inflammatory and diuretic activities of the methanol extract of two varieties of Cicer arietinum viz black or Desi and white or Kabuli were tested in the doses of 200 and 400 mg/kg. For analgesic effect of the extracts, acetic acid induced writhing, tail immersion and hot plate tests were employed in mice. The anti-inflammatory activity was carried out by carrageenan induced inflammation in rats, whereas the diuretic action was determined using metabolic cages for rats. Animals were divided into six groups [n=7]: [1] Control [2] Standard [3] MECAB 200 [4] MECAB 400 [5] MECAW 200 [6] MECAW 400. All extracts and standard drugs were administered orally. Acute oral toxicity of the extracts was also checked in mice up to 2000mg/kg dose, which showed a favorable safety. Significant analgesic and anti-inflammatory effects were observed. The results of diuretic activity were significant at 12th and 24 th hrs. Therefore, it is concluded that the methanol extracts of the seeds of Cicer arietinum have analgesic, anti-inflammatory and diuretic potential

Analgesic and anti-inflammatory activities of fixed oil of Macrotyloma uniflorum [Lam.) Verdc. in mice and rats

Macrotyloma uniflorum commonly known as horse gram or kulthi bean is grown as a pulse for livestock and human consumption. The beans contain about 1.3% fat, 18% protein, 15% carbohydrate along with vitamins and minerals. In traditional medicine it is used as antihyperglycemic, antioxidant, antihypertensive and diuretic. Other important medicinal uses include treatment of renal stones, obesity, piles, oedema and fever. The present study evaluated analgesic [by acetic acid induced writhing, hot plate and tail flick tests in mice] and anti-inflammatory [carrageenan induced paw edema in rats] activities of Macrotyloma uniflorum fixed oil [MUFO]. Four groups were included in study: Group-I: Normal Saline Control [2ml/kg], Group-II: MUFO [2ml/kg], Group-III: MUFO [4ml/kg], and Group-IV: Standard Acetyl salicylic acid [ASA 300mg/kg]. All results were significant however delayed onset of action was observed in tail flick and paw edema tests. Acute oral toxicity of the oil was also checked in mice and was found safe up to 4ml/kg dose, as no signs of toxicity and mortality were observed. It is concluded that Macrotyloma uniflorum fixed oil may possess analgesic and anti-inflammatory activity which can be related with a peripheral mechanism of action

Phycochemical and pharmacological studies on ulva fasciata delile

Phycochemical and pharmacological studies were carried out on Ulva fasciata Delile. The ash content was found as 20.4812 % dry weight, moisture content 14.5514 %, total fat content as 0.1878% and 0.49341 %. Total carbohydrate was found as 54.5301-54.2246% dry weight, phenolic content as 0.022%, flavonoids found to be 0.0313% and tannins were 0.00003 %. Ulva fasicata showed central analgesic activity and significant anti-inflammatory activity at the dose of 400 mg/kg bw

Analgesic, anti-inflammatory and diuretic activities of Macrotyloma uniflorum [Lam.] Verdc.

Macrotyloma uniflorum [Lam.] Verdc. [Papilionaceae] is commonly known as Horse gram and Kulthi. The seeds are reported as anthelmintic, diaphoretic, diuretic and emmenagogue. It is also useful in asthma, bronchitis and urolithiasis. In the present study, analgesic, anti-inflammatory and diuretic effects of the methanol extract of Macrotyloma uniflorum seeds were evaluated in doses of 200 and 400mg/kg. Significant results were obtained in all activities