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Objective: To evaluate the effect of imatinib mesylate on cell viability, anti cancer effect through modulation of KAI1/CD82 gene expression in breast cancer MCF-7 cell line. Methods: The effects of imatinib mesylate on cell viability in MCF-7 cell line were assessed using MTT assay and IC
ABSTRACT
Due to physical and mental complications, stroke causes disability in self-care and adherence to rehabilitation in patients. The purpose of this study was to assess the adherence to rehabilitation regimen in family caregivers of patients with stroke. In this cross-sectional study, 180 family caregivers of patients with stroke were recruited to the study using convenience sampling method. The participants were asked to complete demographic sheet and the Adherence-of-Therapeutic-Regime Questionnaires during two months of stroke. Data were statistically analyzed using descriptive and inferential tests in the SPSS-16. Findings indicated that only about 10% of caregivers were in good levels of adherence to the rehabilitation regimen; and about 25% of them were weak. The weaknesses of the adherence were related to rehabilitation of motion, cognitive and emotional deficiencies, and also prevention of respiratory and skin disorders. According to the study, a small number of family caregivers were in appropriate level for adherence to the rehabilitation regimen. The nurses should be able to empower the family caregivers to decrease physical and psychological disorders related to stroke in patients
ABSTRACT
Quality of nursing care is a major issue in nursing management. In the last year of nursing studies [internships] in Iran, nursing students are going to independently carry out responsibilities of graduated nurses. Patients' satisfaction is a main indicator for nursing care quality. This study was to determine the correlation between the quality of caring behaviors among internship students with the patients' satisfaction with nursing care quality. In this cross-sectional study, 200 patients were selected using convenience sampling method from the hospitals affiliated to the Tehran University of Medical Sciences. Data were gathered using two questionnaires including: 1] quality of the caring behaviors; and 2] patient satisfaction with nursing care quality questionnaire [PSNCQQ]. Data were analyzed using statistical tests in the SPSS-13. Regarding quality of caring behaviors, the subscale scores of the knowledge and skills were good; and patient education was low. The relationship between the nurses and patients, and nursing morality were in average level. Regarding the patient satisfaction, the highest level of satisfaction was related to nursing knowledge and skills; and the lowest level was related to the patient education. Significant correlation was found between the total quality of the caring behaviors with the patients' satisfaction and their subscales [P<0.001]. Based on the findings, patients are more satisfied with the caring behaviors of the students who focus on the communication with patients, nursing ethics, and especially patient education during the care