ABSTRACT
Reports 41 cases of central diabetes insipidus (CDI) admited and treated during the 1 st 12 years.Some of the special clinical features. associated diseases,diagnosis and treatment are discussed.The clinical features of DI may be varied,the diagnosis of DI complicated with other dndocrine diseases may be difficult,pospond diagnosis and treatment may lead to a serious sequel.Owing to using CT scan the morbidity of primary DI may decrease.The drugs often used in treating DI are evaluated In conclusion these drugs not only are If no affect but also have some serious adverse effeets.Desmoprsin is nearly without appreciate-pressure-action especialy administrated orally.Desmopresin is proposed to be the best agent in treating DI up till now.
ABSTRACT
There have been more than 100 cases of idiopathic hypoparathyroidism(IHP) reported in our country. The 8 cases reported in this paper showed some special features in the clinical manifestations, the biochemical parameters, and the response to treatment.Clinical, one case was complicated with Klinefelter's syndrome. Another case suffered from subcorneal pustulosis prior to the onset of idiopathic hypo-parathyroidism. Two cases were misdiagnosed as epilepsy and admitted to the department of neurology. Generalized exfoliative dermatitis was induced in one case by large doses of antiepileptic agents to control the convulsive seizures.Biochemically, both CPK and LDH were elevated in one case. Serum calcium was as low as 2.4 mg/dl in one case, and serum phosphrus was as high as 11.7 mg/d1 in another. These phenomena were rarely encounted in IHP.Therapeutically, transplantation of homogenous parathyroid gland with blood vessels was the method of choice. Two cases were treated in this way with good results. A third case received a dog's parathyroid gland, which also showed good results. The mechanism of heterogenous parathyroid transplantation needs further investigation.In addition, the diagnosis and differential diagnosis of IHP were discussed.