ABSTRACT
<p><b>OBJECTIVE</b>To investigate the relationship between fetal growth restriction and decreased ovarian reserve (DOR) in adulthood to screen high-risk population for early interventions.</p><p><b>METHODS</b>Forty-four patients with FGR and 88 normal women aged 18-40 years were enrolled. All the subjects were examined for serum levels of follicle-stimulating hormone (FSH), inhibin B (INH-B), and anti-mullerian hormone (AMH) using enzyme-linked immunosorbent assay method in the first 3-5 days of the menstrual cycle, and the counts of antrum ovarian follicle were detected by transvaginal or transabdominal ultrasonography.</p><p><b>RESULTS</b>The serum levels FSH, INHB, AMH, and AFC in FGR group differed significantly from those in the control group (P<0.05).</p><p><b>CONCLUSION</b>FGR will affect reproductive endocrine function in adulthood to cause a decreased ovarian reserve.</p>
Subject(s)
Adolescent , Adult , Female , Humans , Young Adult , Anti-Mullerian Hormone , Blood , Case-Control Studies , Enzyme-Linked Immunosorbent Assay , Fetal Growth Retardation , Follicle Stimulating Hormone , Blood , Inhibins , Blood , Menstrual Cycle , Ovarian Follicle , Physiology , Ovarian Reserve , Prospective StudiesABSTRACT
Objective To investigate the efficacy of heparin plus low-dose aspirin on pregnant women with primary antiphospholipid syndrome(APS). Methods Three hundred and twenty women with unexplained pregnant failure were reviewed and anticardiolipin (aCL) immunoglobulin antibody G and M were tested. Heparin plus low-dose aspirin was given to 36 women with positive results. Results One fetal death and one embryo loss occured. The live birth rate was 94.4%(34/36) and the mean gestational week was (35.7?3.2) wks. The average birth weight was (2960?458) g which was significantly higher than the normal pregnancies (2684?324)g ( P