Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 20 de 53
Filter
1.
Rev. Baiana Saúde Pública (Online) ; 47(4): 223-237, 20240131.
Article in Portuguese | LILACS-Express | LILACS | ID: biblio-1537817

ABSTRACT

O sono é um estado essencial para sobrevivência humana, ele exerce função biológica, restauradora e de conservação energética do organismo, promovendo equilíbrio físico e mental. Alta prevalência da má qualidade de sono e sonolência diurna excessiva (SDE) têm sido relatadas por estudantes universitários de diversos cursos, ocasionando prejuízos na concentração e queda dos rendimentos acadêmicos. O objetivo deste trabalho foi avaliar a qualidade de sono, a SDE e suas possíveis associações com sintomas depressivos em estudantes de odontologia. Foi realizado um estudo transversal e descritivo com 251 alunos do curso de odontologia da Faculdade de Farmácia, Odontologia e Enfermagem da Universidade Federal do Ceará. Os instrumentos utilizados foram o Índice de Qualidade de Sono de Pittsburgh (IQSP), Escala de Sonolência de Epworth (ESE) e Inventário de Depressão de Beck (IDB). Verificou-se uma alta prevalência de má qualidade de sono (53,4%) e SDE (35,1%) entre os estudantes, sem diferença significante em relação ao sexo para ambas. Foi encontrada correlação positiva entre IDB com IQSP e ESE (r = 0,478; p = 0,000 e r = 0,202; p = 0,000, respectivamente). Os resultados mostraram uma alta prevalência de má qualidade de sono e SDE e ambos os achados apresentaram associação com sintomas depressivos.


Sleep is an essential state for human survival. It has a biological, restorative and energy conservation function for the organism, promoting physical and mental balance. A high prevalence of poor sleep quality and excessive daytime sleepiness (EDS) has been reported among university students from different courses, causing impaired concentration and a drop in academic performance. This study evaluates sleep quality, EDS and their possible associations with depressive symptoms in dentistry students. A cross-sectional descriptive research was conducted with 251 students from the Dentistry Course at the School of Pharmacy, Dentistry and Nursing, Federal University of Ceará. Variables of interest were assessed by Pittsburgh Sleep Quality Index (PSQI), Epworth Sleepiness Scale (ESS) and Beck Depression Inventory (BDI). Results show a high prevalence of poor sleep quality (53.4%) and EDS (35.1%) among students, with no significant difference regarding gender. BDI had a positive correlation with PSQI and ESS (r= 0.478, p= 0.000; and r= 0.202, p =0.000, respectively). Both findings were associated with depressive symptoms.


El sueño es un estado esencial para la supervivencia humana, tiene una función biológica, reparadora y de conservación de energía para el organismo, favoreciendo el equilibrio físico y mental. Se ha reportado una alta prevalencia de mala calidad del sueño y somnolencia diurna excesiva (SDE) en estudiantes universitarios de diferentes carreras que provoca alteración de la concentración y caída del rendimiento académico. El objetivo de este trabajo fue evaluar la calidad del sueño, la SDE y sus posibles asociaciones con síntomas depresivos en estudiantes de odontología. Se realizó un estudio descriptivo transversal con 251 estudiantes de la carrera de Odontología de la Facultad de Farmacia, Odontología y Enfermería de la Universidad Federal de Ceará. Los instrumentos utilizados fueron el Índice de Calidad del Sueño de Pittsburgh (PSQI), la Escala de Somnolencia de Epworth (ESS) y el Inventario de Depresión de Beck (BDI). Hubo una alta prevalencia de mala calidad del sueño (53,4%) y SDE (35,1%) entre los estudiantes, sin diferencia significativa en relación con el género para ambos. Se encontró una correlación positiva entre BDI con PSQI y ESS (r= 0,478; p= 0,000 y r= 0,202; p = 0,000, respectivamente). Los resultados mostraron una alta prevalencia de mala calidad del sueño y SDE, y ambos hallazgos se asociaron con síntomas depresivos.

2.
Article in English | LILACS-Express | LILACS | ID: biblio-1511723

ABSTRACT

Introduction: traumatic brain injury is a global public health problem due to its severity and high rates of morbimortality worldwide. Identifying predictors associated with increased mortality and unfavorable functional outcomes after the traumatic brain injury event is crucial for minimizing morbidity and mortality rates. Therefore, this study aims to establish a protocol to investigate the predictors of mortality and functional recovery after severe traumatic brain injury in Brazil.Methods: The study will include all patients admitted for severe traumatic brain injury (Glasgow Coma Scale ≤ 8) at the State Hospital of Urgency and Emergency, which is the referral trauma hospital of Espirito Santo. The outcomes of interest are hospital mortality and functional recovery 24 months after hospital discharge. Subjects will be followed up at seventy-two hours, three months, six months, twelve months, and twenty-four months after the trauma. Morbidity will be determined by assessing: 1) the level of motor and cognitive disability, 2) functional impairment and quality of life, and 3) aspects of rehabilitation treatment. Additionally, the traumatic brain injury load, estimated by the years of life lost, will be calculated. Discussion: the results of this study will help identify variables that can predict morbidity and mortality, as well as diagnostic and therapeutic targets for patients with severe traumatic brain injury. Furthermore, the findings will have practical implications for: 1) the development of public policies, 2) investments in hospital infrastructure 3) understanding the socioeconomic impact of functional loss in the individuals.Study registration: the study received approval from the Ethics Committee of the Federal University of Espirito Santo under protocol number 4.222.002 on August 18, 2020.


Introdução: traumatismo cranioencefálico é um problema global de saúde pública devido à sua gravidade e altas taxas de morbimortalidade em todo o mundo. Identificar preditores associados ao aumento da mortalidade e desfechos funcionais desfavoráveis após o evento do traumatismo craniencefálico é primordial para minimizar as taxas de morbidade e mortalidade. Portanto, este estudo tem como objetivo estabelecer um protocolo para investigar os preditores de mortalidade e recuperação funcional após traumatismo cranioencefálico grave no Brasil. Métodos: este estudo tem como objetivo investigar os preditores de mortalidade e recuperação funcional em pacientes com traumatismo cranioencefálico, além de fornecer uma visão geral do traumatismo cranioencefálico no estado do Espírito Santo. O estudo abrangerá todos os pacientes internados por traumatismo cranioencefálico grave (Escala de Coma de Glasgow ≤ 8) no Hospital Estadual de Urgência e Emergência, o hospital de referência para traumas no Espírito Santo. Os desfechos de interesse incluem mortalidade hospitalar e recuperação funcional após 24 meses da alta hospitalar. Os participantes serão acompanhados em setenta e duas horas, três meses, seis meses, doze meses e vinte e quatro meses após o trauma. A morbidade será determinada pela avaliação de: 1) nível de incapacidade motora e cognitiva, 2) comprometimento funcional e qualidade de vida, e 3) aspectos do tratamento e reabilitação. Além disso, a carga de traumatismo cranioencefálico, estimada em anos de vida perdidos, será calculada. Discussão: os resultados deste estudo ajudarão a identificar variáveis que podem predizer a morbidade e a mortalidade após traumatismo cranioencefálico grave. Além disso, as descobertas terão implicações práticas para: 1) o desenvolvimento de políticas públicas, 2) investimentos em infraestrutura hospitalar e 3) compreensão do impacto socioeconômico da perda funcional nesses indivíduos. Registro do estudo: o estudo recebeu aprovação do Comitê de Ética da Universidade Federal do Espírito Santo sob o número de protocolo 4.222.002 em 18 de agosto de 2020

3.
Rev. Soc. Bras. Med. Trop ; 55: e0063, 2022. graf
Article in English | LILACS-Express | LILACS | ID: biblio-1376358

ABSTRACT

ABSTRACT Mass vaccination campaigns are essential to control the ongoing novel severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) pandemic. The Covishield vaccine consists of the replication-deficient simian adenovirus vector ChAdOx1, which contains the full-length structural spike protein of SARS-CoV-2. Occasionally, it can lead to cutaneous reactions that contribute to fear of vaccination, hesitancy, and incomplete vaccination schedules. We report a case of facial angioedema following the first dose of Covishield in a 63-year-old woman with no previous history of allergies or hypersensitivity to drugs or vaccines. No rebound of angioedema was recorded after the second homologous and third heterologous doses.

4.
Rev. Soc. Bras. Med. Trop ; 53: e20190516, 2020. graf
Article in English | SES-SP, ColecionaSUS, LILACS | ID: biblio-1136894

ABSTRACT

Abstract The differential diagnosis of optic neuritis is broad and varied. We report the case of a 24-year-old Brazilian man who presented with five-week history of fever, malaise, myalgia, severe fatigue, tender right preauricular lymphadenopathy, and acute vision blurring associated with right optic disc swelling and exudates in a macular star pattern. His illness developed soon after an infestation of fleas broke out among his cats. Diagnosis of ocular bartonellosis was confirmed by serological and molecular analyses targeting amplification of Bartonella spp. htrA gene. Signs and symptoms only improved after initiation of antimicrobial therapy.


Subject(s)
Humans , Animals , Male , Cats , Young Adult , Retinitis/microbiology , Bartonella henselae/isolation & purification , Retinitis/diagnosis , Retinitis/drug therapy , Doxycycline/therapeutic use , Anti-Bacterial Agents/therapeutic use
5.
Rev. bras. oftalmol ; 78(2): 91-97, mar.-abr. 2019. tab
Article in Portuguese | LILACS | ID: biblio-1003568

ABSTRACT

Resumo Objetivos: Identificar e descrever as alterações oculares em idosos com HIV ou aids através de exame oftalmológico. Avaliar a associação entre as alterações oculares encontradas e o nível de linfócitos T CD4, tempo da terapia antirretroviral, características demográficas e faixa etária. Métodos: Série de 40 casos de pacientes idosos com HIV examinados nos serviços de oftalmologia e imunologia do Hospital Universitário Gaffrée e Guinle (HUGG) de janeiro de 2017 a junho de 2018. Foi realizado o seguinte exame oftalmológico: anamnese, acuidade visual, motilidade ocular, reflexo pupilar, biomicroscopia, tonometria de aplanação e fundoscopia. As análises estatísticas foram realizadas pelo SPSS 20.0. Resultados: A média de idade dos 40 pacientes foi 64,7 anos (dp: 5,1) e o diagnóstico de infeção pelo HIV foi em média há 16.6 anos (dp:7). A maioria dos pacientes examinados possui visão normal (n=22; 55%) e pressão intraocular normal (entre 11 e 21 mmHg). As principais queixas dos pacientes durante a anamnese foram: embaçamento visual (50%), redução da acuidade visual (47.5%), prurido ocular (27.5%), lacrimejamento (25%) e ardência (25%). As alterações biomicroscópicas mais frequentes foram catarata (92.5%), seguida de olho seco (32.5%). Na fundoscopia encontrou-se 43,8 % de alterações da vascularização retiniana, 43.8 % de alterações relacionadas ao nervo óptico e 31,3% relacionadas ao pólo posterior da retina. Conclusão: Alterações oculares foram comuns e podem ser justificadas pela: senilidade, estado inflamatório gerado pela infecção crônica do HIV, efeitos adversos da Terapia antirretroviral prolongada e senescência biológica precoce associada a infecção do HIV.


Abstract Objectives: Identify and describe ocular changes in elderly with HIV or aids through ophthalmological examination. Evaluate the association between ocular alterations and the level of TCD4 lymphocytes, time of antiretroviral therapy, demographic characteristics and age range. Methods: Case series of 40 elderly patients with HIV infection. The study was carried out at the ophthalmology and immunology outpatient clinics of the Gaffrée and Guinle University Hospital (HUGG) from january 2017 to june 2018. The patients were attended at the ophthalmology clinic and underwent a ophthalmological exam including: anamnesis, visual acuity, ocular motility, pupillary reflex, biomicroscopy, aplanation tonometry and fundoscopy. Statistical analyses were performed using SPSS 20.0. Results: The average of the 40 patients was 64.7 years (sd: 5.1), aged between 60 and 78 years, and the average time of HIV infection was 16.6 years (sd: 7 years). Most of the patients examined had normal vision (55%) and normal intraocular pressure (between 11 and 21 mmHg). The main complaints of patients during anamnesis were visual blurring (50%), visual acuity reduction (47.5%), ocular itchiness (27.5%), tearing (25%) and burning (25%).The most frequent changes in biomicroscopy were: cataract (92.5%) and dry eye (32.5%). Funduscopy found 43.8% of retinal vascularization alterations, 43.8% of alterations related to the optic nerve and 31.3% related to retinal posterior pole. Conclusion: Ocular changes were common and can be explained by senility, inflamatory changes caused by chronic HIV infection, adverse effects of antiretroviral therapy and early biological ageing associated to HIV infection.


Subject(s)
Humans , Male , Female , Middle Aged , Aged , HIV Infections/complications , Eye Diseases/etiology , Time Factors , CD4-Positive T-Lymphocytes , HIV Infections/drug therapy , Age Factors , CD4 Lymphocyte Count , Anti-HIV Agents , Antiretroviral Therapy, Highly Active , Diagnostic Techniques, Ophthalmological , Eye Diseases/diagnosis
6.
Rev. Soc. Bras. Med. Trop ; 50(2): 277-279, Mar.-Apr. 2017. graf
Article in English | LILACS | ID: biblio-842840

ABSTRACT

Abstract Botryomycosis is an uncommon, chronic, suppurative, bacterial infection that primarily affects the skin and subcutaneous tissues. It has long been associated with defects of cellular immunity. We report a 28-year-old woman who presented with a chronic, ulcerated lesion with draining sinuses in the right malar region. Predisposing factors were HIV infection with poor immunological control, alcoholism, and a previous trauma to the right cheek. Several courses of antimicrobial therapy provided only partial and temporary remission. Complete clinical remission was only achieved 5 years later when a novel antiretroviral regimen composed of darunavir and raltegravir was initiated.


Subject(s)
Humans , Female , Adult , Pyoderma/drug therapy , AIDS-Related Opportunistic Infections/drug therapy , Botrytis/isolation & purification , Dermatomycoses/drug therapy , Facial Dermatoses/drug therapy , Pyoderma/diagnosis , AIDS-Related Opportunistic Infections/diagnosis , Anti-HIV Agents/therapeutic use , Dermatomycoses/diagnosis , Facial Dermatoses/diagnosis , Darunavir/therapeutic use , Raltegravir Potassium/therapeutic use
8.
Rev. Soc. Bras. Med. Trop ; 49(6): 790-792, Dec. 2016. graf
Article in English | LILACS | ID: biblio-829661

ABSTRACT

Abstract: Chikungunya virus (CHIKV) is a mosquito-borne arthritogenic alphavirus that has recently been introduced to Brazil. We report the case of a 36-year-old male patient from the City of Rio de Janeiro who developed molecularly-confirmed CHIKV disease and whose clinical picture was remarkable because of acute arthritis of an interphalangeal joint that had been damaged by trauma 8 years previously. This case illustrates that acute CHIKV disease may preferentially target previously damaged joints. Careful study of individual cases may provide valuable information on the presentation and management of this emerging zoonosis in Brazil.


Subject(s)
Humans , Male , Adult , Arthritis/diagnosis , Finger Injuries/virology , Finger Joint/virology , Chikungunya Fever/diagnosis , Arthritis/virology , Time Factors , Acute Disease , Chikungunya Fever/complications
9.
Arch. endocrinol. metab. (Online) ; 59(2): 116-122, 04/2015. tab
Article in English | LILACS | ID: lil-746470

ABSTRACT

Objective This study aims to estimate the prevalence of thyroid diseases and anti-TPO status. We searched for an association among presence of immune reconstitution and use of stavudine, didanosine and protease inhibitors with thyroid diseases. Materials and methods A cross-sectional study was performed to analyze the records of 117 HIV-infected patients who had their CD4+ cell count, viral load, anti-TPO, TSH and free T4 levels collected on the same day. Immune reconstitution was considered in those whose T CD4+ count was below 200 cells/mm3, but these values increased above 200 cells/mm3 after the use of antiretrovirals. The odds ratio obtained by a 2x2 contingency table and a chi-square test were used to measure the association between categorical variables. Results The prevalence of thyroid disease was 34.18%; of these, 4.34% were positive for anti-TPO. There was an association of risk between stavudine use and subclinical hypothyroidism (OR = 4.19, 95% CI: 1.29 to 13.59, X2 = 6.37, p = 0.01). Immune reconstitution achieved protection associated with thyroid disease that was near statistical significance OR = 0.45, 95% CI: 0.19 to 1.04, X2 = 3.55, p = 0.059. Conclusion The prevalence of thyroid disease in the sample studied was higher than what had been found in the literature, with a low positive anti-TPO frequency. The historical use of stavudine has an association of risk for the presence of subclinical hypothyroidism, and immune reconstitution has trends towards protection for the presence of thyroid diseases. .


Subject(s)
Adult , Female , Humans , Male , Acquired Immunodeficiency Syndrome/drug therapy , Autoantibodies/isolation & purification , Hypothyroidism/epidemiology , Iodide Peroxidase/immunology , Reverse Transcriptase Inhibitors/therapeutic use , Stavudine/therapeutic use , Thyroid Diseases/epidemiology , Acquired Immunodeficiency Syndrome/blood , Acquired Immunodeficiency Syndrome/complications , Anti-Retroviral Agents/therapeutic use , Asymptomatic Diseases/epidemiology , Asymptomatic Diseases/therapy , Cross-Sectional Studies , Didanosine/therapeutic use , Hypothyroidism/chemically induced , Hypothyroidism/immunology , Prevalence , Reverse Transcriptase Inhibitors/adverse effects , Stavudine/adverse effects , Thyroid Diseases/drug therapy
10.
Salud tecnol. vet ; 1(2): 52-59, jul.-dic. 2013. tab
Article in Spanish | LILACS, LIPECS | ID: lil-765277

ABSTRACT

Se caracterizó los accidentes por animales ponzoñosos en pacientes internados en un hospital de niños en LimaPerú, período 2000 û 2009. De 105 historias clínicas revisadas, 85,7% (90) fueron casos de aracneísmo y 12,4% (13) de ofidismo; además de un accidente por alacrán y uno por larva de lepidóptero. Entre los accidentados por arácnidos, la edad media fue 7,1 años. Se presentó casos de loxoscelismo cutáneo (51,1%) y loxoscelismo víscero hemolítico cutáneo (48,9%), producido por Loxosceles laeta. La hospitalización media fue de 13,2 días. Las lesiones se ubicaron en: cara, cabeza y cuello (25,5%); miembro superior (32,1%); tórax y abdomen (18,9%) y miembros inferiores (23,3%). Los signos y síntomas frecuentes fueron edema (83,3%), dolor (81,1%), eritema (76,7%) y flogosis (56,7%). El 66,7% de los casos recibió suero antiloxoscélico monovalente. Las complicaciones frecuentes fueron infecciones de piel (57,8%), insuficiencia renal aguda (32,2%) y fasceitis necrotizante (3,3%). Hubo dos fallecimientos. Entre los accidentados por ofidios, la edad media fue 8,3 años. El 46,2% fueron casos moderados y 53,8% severos., producidos por Bothrops atrox (92,3%) y Bothrops pictus (7,7%). La hospitalización media fue de 33,8 días. Las lesiones se ubicaron en: cabeza (7,7%), miembro superior (38,5%) y miembros inferiores (53,9%). Los signos y síntomas frecuentes fueron edema (84,6%), dolor (84,6%) y necrosis (69,2%). El 84,6% de los casos recibió suero antibotrópico polivalente. Las complicaciones frecuentes fueron síndrome compartimental (38,5%), fascitis necrotizante (30,8 %) e infecciones de piel (15,4%). Se reportó un fallecimiento.


Was characterized the accidents by poisonous animals in patients hospitalized children in Lima, Peru, period 2000 - 2009. Of 105 medical records reviewed, 85.7% (90) were cases of arachnid and 12.4% (13) of snakebite, and a scorpion and an accident by lepidopteran larvae. Among those injured by spiders, the mean age was 7.1 years. Loxoscelism cutaneous cases was presented (51.1%) and viscero hemolytic loxoscelism (48.9%) produced by Loxosceles laeta. The hospital average length of stay was 13.2 days. The lesions were located in: face, head and neck (25.5%) upper limb (32.1%), thorax and abdomen (18.9%) and lower limbs (23.3%). The common signs and symptoms were edema (83.3%), pain (81.1%), erythema (76.7%) and phlogosis (56.7%). The 66.7% of victims received antiloxoscelis monovalent serum. Frequent complications were skin infections (57.8%), acute renal failure (32.2%) and necrotizing fasciitis (3.3%). There were two deaths. Among those injured by snakes, the mean age was 8.3 years. 46.2% were moderate and 53.8% severe, produced by Bothrops atrox (92.3%) and Bothrops pictus (7.7%). The hospitalization average length was 33.8 days. The lesions were located in: head (7.7%), upper limb (38.5%) and lower limbs (53.9%). The frecuent signs and symptoms were edema (84.6%), pain (84.6%) and necrosis (69.2%). The 84.6% of the stories reported the administration of botropic multipurpose serum. The common complications were compartment syndrome (38.5%), necrotizing fasciitis (30.8%) and skin infections (15.4%). One death was reported.


Subject(s)
Humans , Child, Preschool , Animals, Poisonous , Hospitalization , Spider Bites
11.
Rev. Soc. Bras. Med. Trop ; 46(3): 352-354, May-Jun/2013. tab
Article in English | LILACS | ID: lil-679509

ABSTRACT

Introduction Acquired immunodeficiency syndrome (AIDS) is being increasingly reported among the elderly and major depression (MD) may be associated with suboptimal adherence to treatment. Methods Cross-sectional study on factors associated with MD among 72 HIV-infected elderly individuals. Results Twenty (27.7%) patients were found to have MD. The female gender (odds ratio [OR] = 10.65; p = 0.00586), a low CD4 count during the study (OR = 1.005247; p = 0.01539), and current smoking status (OR = 12.89; p = 0.01693) were independently associated with MD. Conclusions Our data underscore the need to attentively search and treat MD among HIV-infected elderly patients. .


Subject(s)
Aged , Female , Humans , Male , Middle Aged , Depressive Disorder, Major/etiology , HIV Infections/psychology , Bacteriocins , Cross-Sectional Studies , Depressive Disorder, Major/psychology , Educational Status , HIV Infections/immunology , Risk Factors , Viral Load
14.
Arq. odontol ; 49(2): 52-59, 2013. ilus
Article in English | LILACS, BBO | ID: lil-698344

ABSTRACT

Aim: The present study aimed to analyze the stress distribution in the dentoalveolar structures of a maxillary central incisor submitted to two situations of impact loading. Materials and Methods: The following loading forces were applied using a three-dimensional finite element model: a force of 500 N at an angle of 45° on the buccal surface of the crown and a 2000 N force acting in the same direction and surface of the tooth. Results: Harmful stress was observed in the second situation, suggesting damage to both the tooth and adjacent tissue. However, the damage found in soft tissues such as dental pulp, was negligible. Conclusion: Injuries resulting from the traumatic situations were more damaging to the integrity of the tooth and its associated hard-tissue structures.


Subject(s)
Finite Element Analysis , Imaging, Three-Dimensional , Tooth Injuries , Biomechanical Phenomena , Computing Methodologies
15.
Rev. Inst. Med. Trop. Säo Paulo ; 54(4): 231-233, July-Aug. 2012. ilus
Article in English | LILACS | ID: lil-643956

ABSTRACT

Immune reconstitution inflammatory syndrome (IRIS) in HIV-infected subjects initiating antiretroviral therapy most commonly involves new or worsening manifestations of previously subclinical or overt infectious diseases. Reports of non-infectious IRIS are much less common but represent important diagnostic and treatment challenges. We report on a 34-year-old HIV-infected male patient with no history of gout who developed acute gouty arthritis in a single joint one month after initiating highly active antiretroviral therapy.


A síndrome inflamatória da reconstituição imune (IRIS) observada quando do início da terapia antirretroviral em indivíduos com infecção pelo HIV envolve mais comumente manifestações novas ou piora clínica de desordens infecciosas, previamente subclínicas ou não. Muito mais raras são as descrições de casos de IRIS de natureza não-infecciosa, embora representem importantes desafios ao diagnóstico e tratamento. Neste relato descrevemos um paciente HIV-positivo do sexo masculino, de 34 anos, sem antecedentes de gota e que desenvolveu monoartrite de gota um mês após início de terapia antirretroviral de alta atividade.


Subject(s)
Adult , Humans , Male , Antiretroviral Therapy, Highly Active/adverse effects , Arthritis, Gouty/chemically induced , HIV Infections/drug therapy , Immune Reconstitution Inflammatory Syndrome , Acute Disease
16.
Braz. j. infect. dis ; 16(4): 393-395, July-Aug. 2012. ilus
Article in English | LILACS | ID: lil-645431

ABSTRACT

Fluoroquinolone (FQ)-associated tendinopathy and myopathy are uncommon but well recognized complications of the use of this class of antibacterial agents. The case of a 63-year-old previously asymptomatic female patient who developed severe left shoulder tendinopathy after surreptitiously doubling the prescribed dose of levofloxacin for the treatment of community-acquired pneumonia is reported here. Surgical stabilization with suture anchors and subacromial decompression were needed.


Subject(s)
Female , Humans , Middle Aged , Anti-Bacterial Agents/adverse effects , Ofloxacin/adverse effects , Shoulder Pain/chemically induced , Tendinopathy/chemically induced , Community-Acquired Infections/drug therapy , Magnetic Resonance Imaging , Pneumonia, Bacterial/drug therapy , Severity of Illness Index
17.
Rev. Assoc. Med. Bras. (1992) ; 58(1): 70-75, jan.-fev. 2012. tab
Article in English | LILACS | ID: lil-617111

ABSTRACT

OBJECTIVE: Prevalence of chronic complications of HIV infection is increasing and early recognition and treatment of the components of metabolic syndrome (MS) are essential to prevent cardiovascular and metabolic complications. Considering this, we performed a cross-sectional study on the prevalence and risk-factors for MS among HIV-infected subjects. METHODS: A total of 819 patients followed at a large outpatient HIV unit were assessed by an interviewer-administered questionnaire that recorded several demographic, epidemiologic, clinical, laboratory, and social variables. Lipodystrophy diagnosis relied on agreement between patient's self-report and physician's observation of altered body-fat deposits. The presence of three or more of the following characteristics identified MS: increased waist circumference, hypertriglyceridemia, low HDL cholesterol level, hypertension, and hyperglycemia. We used logistic regression analyses to study variables independently associated with MS. RESULTS: The prevalence of MS was 20.6 percent and that of lipodystrophy was 38.5 percent. 61 (36.1 percent) out of 169 patients with MS had also lipodystrophy. Patients with metabolic syndrome were significantly more likely to be older (OR = 1.08), had higher CD4 counts (OR = 1.001), had an increased body mass index (OR = 1.27) and had longer exposure to antiretroviral therapy (OR = 1.01) than those without metabolic syndrome. CONCLUSION: Both traditional risk factors for cardiovascular disease and factors associated with HIV infection itself, such as an increased CD4 cell count and a longer exposure to antiretroviral therapy, seem to be associated with metabolic syndrome in the present study population.


OBJETIVO: A prevalência de complicações crônicas da infecção HIV está aumentando, e o reconhecimento precoce e o tratamento dos componentes da síndrome metabólica (SM) são essenciais para a prevenção de complicações cardiovasculares e metabólicas. Considerando isso, realizamos um estudo transversal sobre prevalência e fatores de risco para SM em indivíduos HIV+. MÉTODOS: Um total de 819 pacientes acompanhados em um ambulatório de HIV foi avaliado por um entrevistador que registrou em questionário dados demográficos, epidemiológicos, clínicos, laboratoriais e variáveis sociais. O diagnóstico de lipodistrofia baseou-se na concordância entre autorrelato do paciente e observação do médico das alterações de gordura corporal. A SM foi identificada pela presença de três ou mais das seguintes características: circunferência abdominal aumentada, hipertrigliceridemia, colesterol HDL baixo, hipertensão e hiperglicemia. Análises de regressão logística foram utilizadas para identificar variáveis associadas à SM. RESULTADOS: A prevalência de SM foi 20,6 por cento e de lipodistrofia foi 38,5 por cento. Entre os 169 pacientes com SM, 61 (36,1 por cento) apresentavam lipodistrofia. Os pacientes com síndrome metabólica tinham, significativamente, maior probabilidade de ser mais velhos (OR = 1,08), ter maior contagem de CD4 (OR = 1,001), ter maior índice de massa corporal (OR = 1,27) e ter maior tempo de exposição à terapia antirretroviral (OR = 1,01). CONCLUSÃO: Tanto fatores de risco tradicionais para doença cardiovascular quanto fatores associados à infecção HIV, como aumento da contagem de CD4 e maior exposição à terapia antirretroviral, parecem estar associados à SM na população estudada.


Subject(s)
Adolescent , Adult , Aged , Female , Humans , Male , Middle Aged , Young Adult , HIV Infections/complications , HIV-Associated Lipodystrophy Syndrome/epidemiology , Lipodystrophy/epidemiology , Metabolic Syndrome/epidemiology , Anti-HIV Agents/adverse effects , Antiretroviral Therapy, Highly Active/adverse effects , Cross-Sectional Studies , HIV Infections/drug therapy , HIV-Associated Lipodystrophy Syndrome/chemically induced , Lipodystrophy/chemically induced , Metabolic Syndrome/complications , Prevalence , Risk Factors
18.
Arq. odontol ; 48(4): 270-279, 2012. ilus
Article in Portuguese | LILACS, BBO | ID: lil-698359

ABSTRACT

Objetivo: O objetivo deste estudo foi avaliar as condições de saúde bucal, acesso a serviços odontológicos e autopercepção em saúde bucal, bem como relacionar a necessidade de tratamento odontológico em pacientes internados em um hospital de emergência, em Fortaleza - Ceará, no ano de 2011. Materiais e Métodos: Pesquisa exploratória do tipo transversal em que foram examinados 301 pacientes internados em duas enfermarias de um hospital de referência terciária em trauma, de abrangência regional e estadual. Asvariáveis exploratórias foram avaliação socioeconômica, acesso e autopercepção em saúde bucal e Índice de Necessidade de Tratamento Odontológico (INTO). A coleta de dados foi realizada por um único examinador,os dados foram processados no SPSS (Statistical Package for Social Science), versão 17.0. A comparação entreas variáveis foi feita através do teste t de Student, com nível de significância de 5,0%. Resultados: A maioria dos pacientes era do sexo masculino, com média de idade de 39,38 anos, com ensino fundamental completo, com período mínimo de internamento de 2 dias e máximo de 4,83 meses (DP ±1,31). Ao serem indagados sobre busca de atendimento odontológico, o serviço público foi o principal meio de acesso e o principal motivo relatado da procura do serviço foi a presença de cavidades de cárie. Grande parte dos pacientes foi classificada, segundo modificação do INTO, nos perfis 3 e 4 (76,4%), ou seja, apresentava cálculo dentário, cavidade pequena de cárie e indicação de exodontia. Houve associação estatisticamente significante entre as variáveis ôpercepção de necessidade de tratamento odontológicoõ e ôclassificação da saúde bucalõ (p<0,001), bem como entre ôperfilõ e ôautopercepção de saúde bucalõ (p<0,001). Conclusão: A partir de tal análise, conclui-se queas condições de saúde bucal desses pacientes são preocupantes, com a necessidade inconteste de cuidados desaúde bucal para a população institucionalizada.


Subject(s)
Humans , Male , Female , Dental Care/statistics & numerical data , Dental Staff, Hospital/statistics & numerical data , Emergency Service, Hospital/statistics & numerical data , Oral Hygiene , Health Services/statistics & numerical data
19.
Rev. Inst. Med. Trop. Säo Paulo ; 53(5): 295-297, Sept.-Oct. 2011. ilus
Article in English | LILACS | ID: lil-602367

ABSTRACT

Loiasis is a filarial disease transmitted by the Chrysops spp. tabanid flies in West and Central Africa. It is most commonly diagnosed by the clinical manifestations of Calabar swellings (transient localized inflammatory edema) or, most dramatically, by the appearance of a migrating worm through the conjunctival tissues or the bridge of the nose. We report the case of a 35-year-old resident in the city of Rio de Janeiro who displayed a moving Loa loa in the bulbar conjunctival tissue two years after returning from a six-month trip to Uganda. Surgical removal of the worm was performed.


A loaíase é uma filaríase transmitida por tabanídeos (mutucas) do gênero Chrysops na África central e ocidental, comumente diagnosticada pela apresentação clínica de edema de Calabar (edema inflamatório transitório e localizado) ou, mais dramaticamente, pela migração de um verme adulto pelo tecido conjuntival ou asa do nariz. Descrevemos o caso clínico de um paciente do sexo masculino, 35 anos, residente no Rio de Janeiro, que se apresentou com um verme adulto de Loa loa migrando sobre o tecido conjuntival bulbar dois anos após retornar de uma viagem de seis meses de duração a Uganda. Procedeu-se a remoção cirúrgica do verme.


Subject(s)
Adult , Animals , History, 20th Century , Humans , Male , Conjunctival Diseases/diagnosis , Eye Infections, Parasitic/diagnosis , Loiasis/diagnosis , Conjunctival Diseases/history , Conjunctival Diseases/parasitology , Eye Infections, Parasitic/history , Loiasis/history , Travel , Uganda
SELECTION OF CITATIONS
SEARCH DETAIL