The study of nerve regeneration with infiltration of normal saline and nerve growth factor after vein graft to the resected sciatic nerve / 대한정형외과학회잡지

PURPOSE: To compare the effect of nerve regeneration with infiltration of normal saline and nerve growth factor after vein graft to the resected sciatic nerve of rat. MATERIALS AND METHODS: Eighty Sprague-Dawley rats were divided into five experimental groups: orthotopic nerve graft as control group, inside-in vein graft with normal saline infiltration, inside-out vein graft with normal saline infiltration, inside-in vein graft with nerve growth factor infiltration and inside-out vein graft with nerve growth factor infiltration group. Animals of each group were sacrificed after electromyography at 2, 4, 8 and 12 weeks after operation. Also the light microscopy and transmission electron microscopy were performed to observe histologic change of grafted sites. RESULTS: This study demonstrates that autogenous vein graft serves as a conduit for nerve regeneration, and inside-out vein graft technique and nerve growth factor induce faster and more numerous axonal regeneration and earlier recovery of muscle power. CONCLUSION: Inside-out vein graft with nerve growth factor infiltration is supposed to be a promising technique to take the place of autogenous nerve graft.

The Sequential Development of Elbow-Ossification Centers in Children / 대한정형외과학회잡지

PURPOSE: We aimed to study the cross-sectional ossification pattern of the elbow, the sequence, and the time in Korean children. MATERIALS AND METHODS: The radiographs of the elbow joint of 1418 children from newborn to age of 16 years taken from January 1993 to February 1999 were reviewed. The presence of 6 secondary ossification centers were recorded with all-or-none approach, and sex and chronologic age were also recorded. We took the point of 50% positive ossification as the reference mean for comparison, and found the point by cubic spline method. X2 test was done to compare the ossification time between boys and girls and injured elbow against normal elbow. RESULTS: The boys had following sequential development of ossification centers; capitulum, radial head, medial epicondyle, olecranon, trochlea, lateral epicondyle at age of 1, 6.7, 7.3, 10.8, 11.2, and 13 years, respectively; and the girls, capitulum, medial epicondyle, radial head, olecranon, trochlea, lateral epicondyle, at age of 1, 4.3, 4.3, 9.5, 9.5, and 10 years, respectively. Appearance of ossification centers except capitulum was delayed approximately for 2 years in boys as compared with that in girls (p0.05) . SUMMARY: The authors reported the patterns for the development of secondary ossification centers of Korean children using the cross-sectional study.

Analysis of Associsted Intra-articular Lesions in Popliteal Cyst under Arthroscope in Adults

PURPOSE: The authors tried to analyze the distribution of associated intra-articular lesions using the arthroscope in excision of popliteal cyst observed in adults. MATERIALS AND METHODS: The authors examined intra-articular lesions identified by arthroscopic examination on 113 adult patients(117 cases) who were diagnosed as having popliteal cyst that didn't respond to the conservative treatment. And for the operation, intra-articular examination using arthroscope was performed in supine position and the authors performed one-stage excision of cyst without position change of patients. RESULTS: In 104 cases(88.9%) of total 117 cases, combined intra-articular lesions were identified, Among these, most cases were 72 cases(69.2%) of degenerative chondral lesion and 31 cases(29.8%) of meniscus tear. Communication between cyst and joint was observed in 63 cases(53.8%). There was neither postoperative complication nor recurrence of cyst during out-patient follow-up periods. CONCLUSIONs: In cases of adult patient who have popliteal cyst that doesn't respond to the conservative treatment, possible associated intra-articular lesions should be considered., and arthroscopic examination and proper treatment far those associated lesions are thought to lower the recurrence rate.

The study of nerve regeneration with infiltration of normal saline and nerve growth factor after vein graft to the resected sciatic nerve / 대한정형외과연구학회지

PURPOSE: To compare the effect of nerve regeneration with infiltration of normal saline and nerve growth factor after vein graft to the resected sciatic nerve of rat. MATERIALS AND METHODS: Eighty Sprague-Dawley rats were divided into five experimental groups: orthotopic nerve graft as control group, inside-in vein graft with normal saline infiltration, inside-out vein graft with normal saline infiltration, inside-in vein graft with nerve growth factor infiltration and inside-out vein graft with nerve growth factor infiltration group. Animals of each group were sacrificed after electromyography at 2, 4, 8 and 12 weeks after operation. Also the light microscopy and transmission electron microscopy were performed to observe histologic change of grafted sites. RESULTS: This study demonstrates that autogenous vein graft serves as a conduit for nerve regeneration, and inside-out vein graft technique and nerve growth factor induce faster and more numerous axonal regeneration and earlier recovery of muscle power. CONCLUSION: Inside-out vein graft with nerve growth factor infiltration is supposed to be a promising technique to take the place of autogenous nerve graft.

The study of nerve regeneration with infiltration of normal saline and nerve growth factor after vein graft to the resected sciatic nerve / 대한정형외과연구학회지

PURPOSE: To compare the effect of nerve regeneration with infiltration of normal saline and nerve growth factor after vein graft to the resected sciatic nerve of rat. MATERIALS AND METHODS: Eighty Sprague-Dawley rats were divided into five experimental groups: orthotopic nerve graft as control group, inside-in vein graft with normal saline infiltration, inside-out vein graft with normal saline infiltration, inside-in vein graft with nerve growth factor infiltration and inside-out vein graft with nerve growth factor infiltration group. Animals of each group were sacrificed after electromyography at 2, 4, 8 and 12 weeks after operation. Also the light microscopy and transmission electron microscopy were performed to observe histologic change of grafted sites. RESULTS: This study demonstrates that autogenous vein graft serves as a conduit for nerve regeneration, and inside-out vein graft technique and nerve growth factor induce faster and more numerous axonal regeneration and earlier recovery of muscle power. CONCLUSION: Inside-out vein graft with nerve growth factor infiltration is supposed to be a promising technique to take the place of autogenous nerve graft.