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Objective:Population-based cancer registration data were used to analyze stomach cancer epidemiology in China. Meth-ods:Stomach cancer data were retrieved from the National Central Cancer Registry Database, and incident and death cases were esti-mated. The trend of stomach cancer was analyzed. Results:Approximately 424,000 new cancer cases and 298,000 cancer deaths oc-curred in China in 2012. The incidence and mortality rates of stomach cancer in urban males and females remained stable in 2000-2012, whereas the rates in rural males increased and less changes were observed in rural females. After age standardization, both inci-dence and mortality rates significantly decreased. The five-year age-standardized relative survival rate was 27.4% (95%CI: 26.7%-18.1%) in 2003-2005. Conclusion:Stomach cancer is a common cancer, which has heavy burden in China, particularly in rural areas. Ef-forts should be exerted for the prevention and control of the disease.
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Objective@#To analyze the associations between molecular subtypes and overall breast cancer survival among premenopausal and postmenopausal breast cancer in Beijing, and to provide basic information for breast cancer clinical researches and control.@*Methods@#All the resident patients diagnosed with breast cancer in four well-established hospitals were retrieved from Beijing cancer registry, related information, such as TNM stages, receptor status, histological grade, height, weight, were collected by case extraction. Cancer registration information and population-based follow-up information were used to acquire survival outcome. All the patients were followed up until 31 December 2015, 4 531 cases with invasive, primary breast were included in the final analysis. All the cases were classified into Luminal and non-Luminal according to receptor status. Five-year survival rates of the two subtypes were estimated by the life-table method. Multivariable Cox proportional hazards models were employed to evaluate the associations between molecular subtypes and breast cancer survival.@*Results@#Of all the 4 531 patients, premenopausal patients accounted for 44.5% (2 017 cases) and postmenopausal patients accounted for 55.5% (2 514 cases). 643 cases died during the study period. Overall five-year survival was 89.5% (95%CI: 88.6%-90.4%), for premenopausal and postmenopausal patients, they were 92.1% (95%CI: 90.9%-93.3%), and 87.5% (95%CI: 86.2%-88.8%), respectively. Among all the patients, 3 730 patients had molecular subtype, 76.7% (2 861 cases) were Luminal breast cancer, and 23.3% (869 cases) were non-Luminal breast cancer. Five-year survival rates for Luminal and non-Luminal were 91.8% (95%CI: 90.8%-92.8%), and 83.2% (95%CI: 80.7%-85.7%), respectively. No matter in premenopausal or postmenopausal patients, non-Luminal breast cancer had significantly higher risk of death compared to Luminal breast cancer (premenopausal: HR=1.85, 95%CI: 1.26-2.73; premenopausal: HR=1.42, 95%CI: 1.07-1.88).@*Conclusion@#For both premenopausal and postmenopausal breast cancer patients, non-Luminal breast cancer had lower five-year survival rates than Luminal breast cancer, which was a risk factor on breast cancer survival.
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Objective@#Lung cancer incidence and mortality were estimated by sorting and analyzing the national cancer registration data in 2013.@*Methods@#Lung cancer data of 2013 were retrieved from the database of 255 qualified cancer registries. Lung cancer incidence and mortality rates in cancer registration areas in 2013 were estimated by areas (urban/rural), gender and age groups, new lung cancer cases and deaths were estimated using age-specific rates by areas and gender using the corresponding population in 2013. Lung cancer incidence and mortality rates in China in 2013 were calculated based on the estimated new cancer cases and deaths and the corresponding population. The Chinese population in 2000 and Segi′s world population were used to calculate age-standardized rates.@*Results@#It was estimated that there were about 732.8 thousand new lung cancer cases and 580.7 thousand deaths occurred in China in 2013. The crude incidence rate was 53.86/105(males 70.10/105, females 36.78/105), while age-standardized incidence rate by Chinese standard populations (ASIRC) and by world standard populations (ASIRW) were 36.19/105 and 36.09/105 with the cumulative incidence rate (0-74 years old) of 4.42%.The crude mortality rate was 43.41/105(males 57.64/105, females 28.45/105), and age-standardized mortality rate by Chinese standard populations (ASMRC) and by world standard populations (ASMRW) were 28.64/105 and 28.41/105 with the cumulative incidence rate (0-74 years old) of 3.34%.Both incidence and mortality rates were higher in males than in females. Crude incidence and mortality rates were slightly higher in urban areas than in rural areas, but after age standardized, the results were opposite.@*Conclusions@#Lung cancer is the common cancer, which both incidence and mortality rates are ranking first in China, and the burden of the disease is heavy. Comprehensive measures towards risk factors control, cancer early diagnosis and treatment should be strengthened continuously.
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Breast cancer is the most common type of cancer among women in China and around the world. Population-based survival analysis can reflect the overall level of cancer prevention, diagnosis, and treatment in countries or regions, providing basic information for making efficient health policies. Breast cancer survival varies among countries or regions because of differences among races, so-cioeconomic factors, healthcare services, and cancer diagnosis and treatment. Breast cancer prognosis is closely related to tumor stage, status of receptors, and treatments. By determining the relationship between breast cancer survival and related factors, the re-sults can help in predicting the prognosis and evaluating the quality of care services. The article provides an overview of breast cancer survival in China and abroad, as well as references for cancer surveillance.
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<p><b>OBJECTIVE</b>Based on the cancer registry data to analyze the mortality and survival of liver cancer in China.</p><p><b>METHODS</b>Liver cancer data of 2011 were retrieved from the National Cancer Registry Database.Liver cancer deaths were estimated using age-specific rate by areas and gender according to the national population in 2011. Mortality data from 22 cancer registries during 2000-2011 were used to analyze the mortality trend, and data from 17 cancer registries during 2003-2005 were used for survival analysis.</p><p><b>RESULTS</b>The estimates of liver cancer deaths were about 322 thousand in 2011 with a crude mortality rate of 23.93/10(5).There was an increasing trend of crude mortality rate of liver cancer during 2000-2011 in 22 Chinese cancer registries with an average annual percentage change of 0.7% (95%CI: 0.2%-1.2%), 1.1% in urban and 0.4% in rural areas. After age standardization with Segi's population, the mortality rate was significantly decreased, with an APC of -2.3%, -1.9% in urban and -2.2% in rural populations. The 5-year age standardized relative survival was 10.1% (95%CI: 9.5% to 10.7%), and the 1-, 3- and the 5-year observed survival rates were 27.2%, 12.7%, and 8.9%, respectively.</p><p><b>CONCLUSION</b>Liver cancer is a major cancer threatening people's lives and health in China, and the liver cancer burden is still high.</p>
Subject(s)
Humans , China , Epidemiology , Databases, Factual , Incidence , Liver Neoplasms , Mortality , Registries , Rural Population , Survival Analysis , Survival Rate , Urban PopulationABSTRACT
<p><b>OBJECTIVE</b>The national population-based cancer registration data were used to analyze the liver cancer incidence and trend in China, in order to provide advise for making further strategy on liver cancer prevention and control.</p><p><b>METHODS</b>Liver cancer data of 2011 were retrieved from the database of the National Cancer Registry. The incident cases of liver cancer were estimated using age-specific rate by urban or rural areas and gender according to the national population in 2011. Liver cancer incidence data from 22 cancer registries were used to analyze the incidence trend during 2000-2011.</p><p><b>RESULTS</b>The estimates of new cases of liver cancer were about 356 thousand in China in 2011. The incidence rate was 26.39/10(5,) and the age-standardized incidence rates by Chinese standard population and by world population were 19.48/10(5) and 19.10/10(5,) respectively.There was an increasing trend of incidence rate of liver cancer in China during 2000-2011 with an average annual percentage change(AAPC) of 1.0% (95%CI: 0.5%-1.4%), 1.2% (95%CI: 0.7%-1.8%)in urban areas and 1.1% (95%CI: 0.5%-1.8%) in rural areas. After age standardization, the incidence rate was significantly decreased, with an AAPC of -1.8% (95%CI: -2.4% to -1.2%), -1.6% (95%CI: -2.2% to -0.9%) in urban and -1.4% (95%CI: -2.5% to -0.3%) in rural areas.</p><p><b>CONCLUSIONS</b>Liver cancer is a common cancer in China. As changing in people's dietary habits and implementing neonatal HBV vaccination for years, the exposure to risk factors is reducing, and age-standardized incidence rate is decreasing. While cardinal number of population is big and aging population is growing rapidly in the country, trend of incidence rate is increasing, and the burden of liver cancer is still high in China.</p>