1.
Synthesis of certain 4 [3H] quinazolinone compounds containing imidazolinone and azomethine moieties
Egyptian Journal of Pharmaceutical Sciences. 1988; 29 (1-4): 587-94
in English
| IMEMR
| ID: emr-10341
ABSTRACT
The synthesis of several 3-[4-arylindine-2-alkyl [aryl] 5[4H] imidazolon-1-yl] phenyl]-2-methyl-7-nitro-4 [3H]-quinazolinones are described. Structured establishment of the new compounds is substantiated by element analysis, IR and h- NMR spectra. Preliminary biological screening of some selected members showed no detectable antimicrobial activity in vitro, chloramphenicol and nystatin were included in the study for sake of comparison
Subject(s)
Quinazolines , Chemistry, Pharmaceutical
2.
Egyptian Journal of Pharmaceutical Sciences. 1988; 29 (1-4): 595-604
in English
| IMEMR
| ID: emr-10364
ABSTRACT
Several new 3-substituted 7-nitro-4 [3H] quinazolinones were prepared. The structures of the obtained compounds based on elemental analysis, IR and H-NMR spectra. Anti-convulsant and hypnotic activities of some compounds were tested and compared to phenytoin and pentobarbital sodium