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Asian Pacific Journal of Tropical Medicine ; (12): 135-138, 2013.
Article in English | WPRIM | ID: wpr-820554

ABSTRACT

OBJECTIVE@#To assess the usefulness of IGRA test (QuantiFERON(®)-Cell mediated immune) compared with the tuberculin skin test.@*METHODS@#A cross-sectional study was carried out in Mexico, 25 infected patients with HIV-AIDS and the suspicion or with latent tuberculous infection (LTBI) who were >18 years of age and without treatment for tuberculosis (TB), were enrolled in the study.@*RESULTS@#Median cluster of differentiation (CD4) count was 364 cells/μ L and median HIV viral load was 50 copies/mL. Overall, 20 patients (80%) had at least one positive diagnostic test for LTBI: four (16%) had a positive tuberculin skin test and 19 (76%), a positive QuantiFERON(®)-tuberculosis.@*CONCLUSIONS@#No agreement is found between the two diagnostic tests: k = -0.004, 95% confidence interval (-0.2219, 0.2210). Additional longitudinal studies among HIV-infected populations with high prevalence of TB are needed to further assess the usefulness of IGRAs in this patient population.


Subject(s)
Adult , Aged , Female , Humans , Male , Middle Aged , CD4 Lymphocyte Count , Cross-Sectional Studies , HIV Infections , Diagnosis , Allergy and Immunology , Microbiology , Interferon-gamma , Allergy and Immunology , Metabolism , Interferon-gamma Release Tests , Latent Tuberculosis , Diagnosis , Allergy and Immunology , Virology , Statistics, Nonparametric , Tuberculin Test , Viral Load
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