ABSTRACT
<p><b>OBJECTIVE</b>To explore the relationship between abdominal fat volume and obstructive sleep apnea hypopnea syndrome in obesity people.</p><p><b>METHODS</b>From July 2009 to July 2010, 50 patients with BMI > 25 were prospectively selected for study from the patients who complained of snoring in the Respiratory department. The patients were divided into OSAHS group and non-OSAHS group according to the result of sleep apnea monitoring. All the patients also received full abdominal CT and the whole abdominal fat volume was measured by 3-D CT reconstruction system. SPSS 13.0 was used for statistical analysis.</p><p><b>RESULTS</b>The whole abdominal fat volume in the two groups was analyzed by T- test, which was significantly different between the two groups (P < 0.01). It showed that there was a statistical relationship between OSAHS and abdominal fat in obesity people.</p><p><b>CONCLUSION</b>In obesity people, OSAHS has a close relationship with abdominal fat volume. The abdominal fat volume is markedly higher in OSAHS patients than that in non-OSAHS people.</p>
Subject(s)
Adult , Female , Humans , Male , Middle Aged , Abdominal Fat , Diagnostic Imaging , Case-Control Studies , Obesity , Diagnostic Imaging , Prospective Studies , Radiography , Sleep Apnea, Obstructive , EpidemiologyABSTRACT
Objective: To study the expression levels of IL (serum interleukin)-17 and IL-6 of patients with CRC (colorectal cancer), and to investigate the correlation between the levels of serum IL-17 and IL-6 and the development of human CRC. Methods: The expression levels of serum IL-17 and IL-6 of 56 patients with CRC and 30 healthy volunteers (controls) were detected by ELISA. The potential associations between serum IL-17 and IL-6 levels and the clinicopathological characteristics were analyzed. Results: The levels of serum IL-17 and IL-6 of 56 patients with CRC were significantly higher than those of the controls (96.43±21.15 vs 16.88±5.07 ng/L, 139.53±27.84 vs 39.21±7.46 ng/L; P 0.05) but associated with the tumor size, metastasis, Dukes stage and pathological type (P < 0.01). Conclusion: The levels of serum IL-17 and IL-6 increase with the development of CRC, which suggests that IL-17 and IL-6 may directly or indirectly contribute to the development and progression of CRC. © 2012 by Tumor.
ABSTRACT
Based on a blind research of in-vitro diagnostic devices in use,this paper analyses the error rates of clinical laboratory items in hospitals of different levels, and gives some advies and suggestions for clinical laboratory administration.