ABSTRACT
Objective@#To analyze the characteristics of the "Interner Plus-based AIDS Comprehensive Prevention Service System" among MSM who frequently using the Internet in Guangzhou.@*Methods@#An online survey was conducted among MSM who were recruited through gay-website portals between August and September, 2018 in Guangzhou, to collect information regarding the use of and attitudes on the "Interner Plus-based AIDS Comprehensive Prevention Service System" . Logistic regression was used to explore the association between the use of Internet intervention tools and related behavioral characteristics. Information on the awareness of AIDS, HIV testing, and condomless anal sex behavior were compared between the core or non-core services users.@*Results@#A total of 777 Internet-based MSM were recruited as participants including 638 men (82.1%) as core service users. MSM were satisfied in using the the "Interner Plus-based AIDS Comprehensive Prevention Service System" while more than 80.0% of the users felt that the tools were helpful in: increasing the HIV awareness, promoting test uptake, and reducing those related risk behavior. Comparing with those who did not use the tools, the users showed higher rates in practising condomless anal intercourse (1.50-1.86 times), commercial sex with men (11.60-21.21 times), and unprotected vaginal intercourse (13.62-20.67 times), in the last 6 months. Proportions of core service users appeared as: [96.6% vs. 74.8%, aOR (95%CI): 8.80 (4.85-15.97)] on HIV testing, [56.4% vs. 22.3%, aOR (95%CI): 4.54 (2.94-7.02)] on regular HIV testing and [86.2% vs. 80.6%, aOR (95%CI): 1.75 (1.06-2.89)] on awareness of HIV knowledge respectively, which were all significantly higher than the non-core service users.@*Conclusions@#The frequent Internet using MSM in Guangzhou claimed to have had high acceptance and satisfaction on the local Internet HIV intervention service tools. The "Internet Plus-based AIDS Comprehensive Prevention Service System" had effectively reached the high-risk subgroups of MSM, increasing the awareness on related risk and promoting testing on HIV.
ABSTRACT
Objective To investigate the significance of cerebrospinal fluid albumin (CAlb) and cerebrospi-nal fluid immunoglobulin G (CIgG ) in the diagnosis of nervous system inflammatory diseases .Methods A retrospective analysis of 104 patients with cerebrospinal fluid examination from April 2016 to March 2017 in the hospital who were divided into 59 cases of inflammatory disease and 45 cases of non-inflammatory .Blood clearance protein (SAlb) ,CAlb and G IgG were examined(QAlb=CAlb/SAlb) and compared .Results After logarithmic transformation ,ln(CIgG) 4 .36 ± 1 .00 ,ln(CAlb) 6 .31 ± 0 .77 ,ln(QAlb) 2 .57 ± 0 .79 in inflamma-tory group ,compared with non-inflammatory group ,ln(CIgG) 3 .53 ± 0 .59 ,ln(CAlb) 5 .52 ± 0 .50 ,ln(QAlb) 1 .88 ± 0 .47 ,the difference ,were statistically significant (P< 0 .05) .Conclusion The degree of blood-brain barrier damage is different in different nervous system diseases ,and the synthesis of IgG is different ,CIgG , CAlb ,QAlb can be used as an indicator to judge the blood-brain barrier damage ,and can also be used in the differential diagnosis of inflammatory and non-inflammatory diseases of the nervous system .The increase of CIgG also suggests that the occurrence of the disease may be related to autoimmunity .