Intratympanic methylprednisolone hemisuccinate injection in treating the refractory noise induced deafness / 中华劳动卫生职业病杂志

<p><b>OBJECTIVE</b>To analyze the efficacy of Methylprednisolone hemisuccinate intratympanic injection for refractory noise induced deafness.</p><p><b>METHODS</b>One hundred and twenty cases (215 ears) of noise induced deafness were treated with either hormone group (107 ears) or with non hormone group (108 ears). Following prior interventions, 145 ears went on to receive intratympanic Methylprednisolone hemisuccinate injection twice a week.</p><p><b>RESULTS</b>After Intratympanic therapy, the total effective rate was 46.2%. 32 of 71 ears (45.1%) demonstrated hearing improvement in hormone group and 35 of 74 ears (47.3%) in non hormone group. The difference was statistically insignificant (P = 0.788).</p><p><b>CONCLUSION</b>Intratympanic therapy appears to provide additional treatment benefits for patients with refractory noise induced deafness who have been treated with prior interventions. The outcome is not affected by pretreatment with hormone.</p>

Application of ocular-vestibular evoked myogenic potentials in patients with Meniere's disease / 临床耳鼻咽喉头颈外科杂志

OBJECTIVE@#To evaluate the reliability and the value of clinical application of ocular-vestibular evoked myogenic potentials in the patients with Meniere's disease.@*METHOD@#Thirty healthy people (control group) and Twenty-seven patients with lateral Meniere's disease (therapy group) were underwent clinical audiological audiometer test and the ocular-vestibular evoked myogenic potential test.@*RESULT@#In the control group, the average potential of n10 wave was (10.13 +/- 0.48)ms, and the average potential of p15 wave was (15.23 +/- 0.46)ms. The average amplitude of n10-peak to p15-peak were (6.58 +/- 2.65) microV. According to the control group, eight patients had abnormal waveform, and nineteen with normal in the therapy group.@*CONCLUSION@#The oVEMPs test is a modest stimulus to the subject which is brief, safe and objective. It represented the function of the utricle and the superior vestibular nerve, the procedure is easily repeatable and acceptable, and worthily applied in patients with Meniere's disease.