ABSTRACT
Objective To establish the determination method of syringin and syringaresinol in Ciwujia Injection with RP-HPLC. Methods C18 ODS was used as a stationary phase. The mobile phase consists of water and acetonitrile. The gradient condition was 0→20 min, A:90%→50%. The flow rate was 1.0 mL/min. The detective wavelength was set at 220 nm. Results The linear range of syringin was 0.03～0.16 ?g (r =0.999 7, n=5) and the linear range of Syringaresinol was 0.02～0.13 ?g (r =0.999 3, n=5). The average recovery of syringin was 99.34% and RSD=0.58%. The average recovery of Syringaresinol was 99.22% and RSD=0.71%. Conclusions The method was simple, convenient and accurate, and can be used for content determination of syringin and syringaresinol in Giwujia injection.
ABSTRACT
OBJECTIVE:To evaluate the cost-effectiveness of3kinds of traditional Chinese medicinal injectable prepa?rations in the treatment of children's fever caused by exogenous pathogens METHODS:44cases were assigned to receive Qin_ gkailing injection(Group A),Shuanghuanglian for injection(Group B)and heartleaf houttuynia herb injection(Group C),re?spectively.The curative effects of the3groups were observed and the cost-effectiveness analysis were conducted as well.RESULTS:The costs for the3groups were28.68yuan,45.00yuan and59.40yuan,respectively;the total effective rates were80.00%,86.67%and85.71%,respectively;the cost-effectiveness ratios of the3were35.85,51.92and69.30,re?spectively;the incremental cost-effectiveness ratios of Group B and C were244.68and538.00,respectively as compared with Group A.CONCLUSION:Qingkailing injection(Group A)is the preferred option in the treatment of children's fever caused by exogenous pathogens.
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OBJECTIVE:To evaluate the cost-effectiveness of 3 kinds of traditional Chinese medicinal injections in the treatment of angina pectoris caused by coronary heart disease(CHD).METHODS:223 CHD patients with angina pectoris were divided into 3 groups:group A(Xuesaitong injection),group B(Breviscapine for injection) and group C(Shuxuening injection). The curative effects were observed and the cost-effectiveness analyses of the 3 groups were conducted as well.RESULTS:The costs for the 3 groups were 1 345.50 yuan,1 768.125 yuan,1 770.00 yuan,respectively; the total effective rates were 83.75%,82.09% and 85.53%,respectively; the cost-effectiveness ratios were 16.07,21.54 and 20.69,respectively;the incremental cost-effectiveness ratios of group B and C were 254.60 and 238.48,respectively as against group A. CONCLUSION:Xuesaitong injection(group A) is the preferred therapy for angina pectoris caused by CHD.