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Objective To explore the effect of Qutan-Tongyang decoction on cardiac function and myocardial remodeling in patients with chronic heart failure. Methods According to the random table method, 96 patients with chronic heart failure were divided into the control group (n=48) and the research group (n=48). The patients in the control group were treated with conventional treatment, and the patients in the research group were treated with Qutan-Tongyang decoction on the basis of the control group. Two groups of patients were treated for 4 weeks. The clinical total effective rate of two groups of patients after treatment was counted. The LVESD, LVEDD, LVEF, IVST, LVPWT, LVMI, BNP, Ang2 were determined respectively before and after treatment. In addition, the adverse reaction incidence of two groups of patients were observed. Results The total effective rate of research group was 89.58% (43/48), while the total effective rate of control group was 72.92% (35/48), the difference between two groups was statistically significant (χ2=4.376, P=0.036). After treatment, the LVESD (45.12 ± 3.02 mm vs. 48.05 ± 3.11 mm, t=4.683), LVEDD (52.24 ± 3.65 mm vs. 56.79 ± 4.15 mm, t=5.704), IVST (7.13 ± 0.63 mm vs. 8.02 ± 0.71 mm, t=6.496), LVPWT (8.15 ± 0.58 mm vs. 8.62 ± 0.75 mm, t=3.434), LVMI (97.65 ± 6.28 g/m2 vs. 112.26 ± 8.47 g/m2, t=9.600), BNP (120.21 ± 19.87 ng/L vs. 188.95 ± 24.18 ng/L, t=15.217), Ang2 (252.52 ± 53.74 pg/ml vs. 330.39 ± 60.85 pg/ml, t=6.645) of the research group were significantly lower than those of the control group (P<0.05), while the LVEF (46.79% ± 3.88% vs. 41.52% ± 3.04%, t=7.407) of the research group were significantly higher than the control group (P<0.05). During treatment, there was no significantly difference of adverse reaction rates of the two groups (χ2=0.545, P=0.460). Conclusions The clinical curative effect of Qutan-Tongyang decoction on the basis of conventional treatment for the treatment of chronic heart failure is significantly, which can significantly improve cardiac function and inhibit cardiac remodeling. It has the high security of the curative effect.
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Objective To explore the intervention effect of low-dose vitamin D on glucose metabolism of patients with impaired glucose regulation. Methods A total of196 subjects receiving oral glucose tolerance test were enrolled in this study, including individuals with normal glucose tolerance ( NGT group, n=67) and indi-viduals with impaired glucose regulation (IGR group, n=129). The IGR group was divided into intervention group ( n=64) and non-intervention group ( n=65) according to vitamin D intervention ( for 1 year) performed or not. Clinical data and biochemical parameters were collected. Results The level of serum 25(OH)D3 was significantly lower in the IGR group than that of normal control group ( P<0. 05) . After 1 year of low-dose vita-min D intervention, insulin sensitivity increased and insulin resistance decreased in the intervention group as compared with non-intervention group. Diabetes developed less frequently in the intervention group ( 25 of 64 [ 39. 1％] ) compared with non-intervention group ( 30 of 65 [ 46. 2％] ) . But there was no significant differ-ent in diabetes prevalence between the two groups. Conclusions Vitamin D intervention can improve insulin sensitivity and reduce insulin resistance in patients with impaired glucose regulation. Low dose vitamin D can improve the abnormal glucose metabolism outcome in patients with impaired glucose regulation.
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Objective@#To explore the effect of Qutan-Tongyang decoction on cardiac function and myocardial remodeling in patients with chronic heart failure.@*Methods@#According to the random table method, 96 patients with chronic heart failure were divided into the control group (n=48) and the research group (n=48). The patients in the control group were treated with conventional treatment, and the patients in the research group were treated with Qutan-Tongyang decoction on the basis of the control group. Two groups of patients were treated for 4 weeks. The clinical total effective rate of two groups of patients after treatment was counted. The LVESD, LVEDD, LVEF, IVST, LVPWT, LVMI, BNP, Ang2 were determined respectively before and after treatment. In addition, the adverse reaction incidence of two groups of patients were observed.@*Results@#The total effective rate of research group was 89.58% (43/48), while the total effective rate of control group was 72.92% (35/48), the difference between two groups was statistically significant (χ2=4.376, P=0.036). After treatment, the LVESD (45.12 ± 3.02 mm vs. 48.05 ± 3.11 mm, t=4.683), LVEDD (52.24 ± 3.65 mm vs. 56.79 ± 4.15 mm, t=5.704), IVST (7.13 ± 0.63 mm vs. 8.02 ± 0.71 mm, t=6.496), LVPWT (8.15 ± 0.58 mm vs. 8.62 ± 0.75 mm, t=3.434), LVMI (97.65 ± 6.28 g/m2 vs. 112.26 ± 8.47 g/m2, t=9.600), BNP (120.21 ± 19.87 ng/L vs. 188.95 ± 24.18 ng/L, t=15.217), Ang2 (252.52 ± 53.74 pg/ml vs. 330.39 ± 60.85 pg/ml, t=6.645) of the research group were significantly lower than those of the control group (P<0.05), while the LVEF (46.79% ± 3.88% vs. 41.52% ± 3.04%, t=7.407) of the research group were significantly higher than the control group (P<0.05). During treatment, there was no significantly difference of adverse reaction rates of the two groups (χ2=0.545, P=0.460).@*Conclusions@#The clinical curative effect of Qutan-Tongyang decoction on the basis of conventional treatment for the treatment of chronic heart failure is significantly, which can significantly improve cardiac function and inhibit cardiac remodeling. It has the high security of the curative effect.
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Objective To have a research on the improvement of visual field of advanced primary glaucoma with tubular visual field after the surgery.Methods Twenty-six patients in the hospital during Nov.2010-Dec.2011 were treated with the compound trabeculectomy.Have a comparison between the preoperative period and postoperative period about the visual field index,visual acuity,intra-ocular tension,bleb After 6-18 mouths following-up,have a summary on the complication rate.Results The visual field index,visual acuity,intra-ocular tension,bleb in the postoperative period were much better than that in the preoperative period.There were no serious complications after the surgery.Conclusion To use the compound trabeculectomy to treat the advanced primary glaucoma with tubular visual field patients is worthy to be promoted and applicated in clinical practice.This method is full of safety and availability.