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Objective:To explore the effect of aerobic exercise on the food intake of obesity rats and obesity resistant rats and some mechanisms Method:The four years old Sprague-Dawley rats were randomly divided into standard chow group (C) and high-fat diet group.After 10 weeks feeding,the obese group (OB group) and obesity resistant group (OR group) induced by high-fat diet were screened out.Then all the rats in OB group and OR group were respectively and randomly divided into exercise rats (OB-Sw group,OR-Sw group) and non-exercise rats (OB-Sed group,OR-Sed group).Aerobic swimming exercise for the exercise rats was defined as 60％ of individual exhaustion exercise intensity,45 minutes per day,5 times per week.Meanwhile,the body weight and food intake of the exercise and non-exercise rats were monitored every week.After 8 weeks intervention,the serum and gastric tissue of rats were obtained,and then the TG,TC,LDL-c,HDL-c in serum and the expression of ghrelin in gastric tissue were detected.Result:Ten weeks later,the body weight of the rats with high-fat diet showed a significant difference compared with the rats with standard chow group (P ＜ 0.05).The content of LDL in OB-Sed group was significantly higher than that in C group (P＜0.05).After 8 weeks aerobic exercise,for the food intake,OB-Sed group was higher than OB-Sw group and OR-Sed group was higher than OB-Sw group.The expression of ghrelin in gastric tissue in OB-Sed group and OR-Sed group was higher than that in OB-Sw group,OB-Sw group and C group.Conclusion:Exercise might reduce the food intake of obesity rats and obesity resistant rats by reducing the expression of ghrelin in stomach.
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Objective To study the influence of anesthetic effect,maternal and infant outcomes and safety of subarachnoid block used sulfentanyl combined with ropivacaine for patients with gestational hypertension in the cesarean section.Methods 180 cases of gestational hypertension ready to cesarean section were selected as study subjects,and they were randomly divided into A group,B group and C group by digital table method,60 cases in each group.A group used 10mg ropivacaine,B group used 13mg ropivacaine,C group used 5μg sulfentanyl combined with 10mg ropivacaine.The anesthetic effect,circulation function,duration of pain,operation time,neonatal Apgar score at 1 and 5 min after birth,neonatal weight,motor block evaluation after operation,adverse reaction and complication were compared in three groups.Results The anesthetic effect between B group and C group had no statistical difference (x2 =1.233,1.465,all P ＞ 0.05).The anesthetic effect of B group and C group was better than that of A group(F =5.633,7.299,all P ＜0.05).The HR and MAP of every time points between A group and C group had no statisticaldifferences (F =1.313,1.265,all P ＞ 0.05).Compared with T0,the HR and MAP of B group at T1,T2,T3,T4 had statistical differences compared with A group and C group(F =5.633,7.299,all P ＜0.05).The operation time of the three groups had no statistical difference(F =0.933,P ＞ 0.05).The duration of pain between B group and C group had no statistical difference(t =0.822,P ＞ 0.05).The duration of pain of A group was longer than that of B group and C group(F =8.316,P ＜0.05).The neonatal Apgar scores at 1 and 5 min after birth and neonatal weight of the three group had no statistical differences(F =0.822,0.929,all P ＞ 0.05).The improved Bromage score between A group and C group had no statistical difference (t =2.627,1.991,all P ＞ 0.05).The improved Bromage score between B group and A,C group had statistical differences(F =6.371,5.693,all P ＜ 0.05).The complete recovery time of motor nerve of B group was much longer than that of A group and C group (F =8.924,P ＜ 0.05).The incidence rates of vomit and nausea of A group and B group were much higher than that of C group(F =3.561,12.581,all P ＜ 0.05).The incidence rate of bradycardia and hypotension of B group was much higher than that of A group and C group (F =8.273,10.833,all P ＜ 0.05).Conclusion During subarachnoid block anaethesia using 5 μg sulfentanyl combined with l0mg ropivacaine can be applied to mild and moderate gestational hypertension,it has advantages such as less adverse reaction,good analgesic effect,less hemodynamic effect,and it is worthy of clinical promotion.
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nges in standard square field.
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Purpose: To understand the influence to depth doses and peripheral doses by Enhanced Dynamic Wedge and physical wedge.Methods: The depth doses and peripheral doses were measurement for open field and Enhanced Dynamic Wedge field as well as physical wedge.Results: ⑴ depth doses and peripheral doses for Enhanced Dynamic Wedge fields was very similar to those for open fields ⑵ depth doses and peripheral doses for physical wedge fields was large than those for open fields. Conclusion: depth doses measured for open fields can also be used for Enhanced Dynamic Wedge fields dose calculation. Wedge depth dose must be used in the physical wedge fields dose calculation. It should be pay attend to peripheral doses for physical wedge fields in the clinic.
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Purpose: To analyses the variation regularity of output factor of lead block fields for high energy electron beam of Varian 2300 C/D linear accelerator. Methods: Output factors of lead block fields were measured for four standard applicators under various electron beam energy. Results: The variations of output factor with field side or with applicators size were no obvious regularity Output factor of lead block fields was related to standard applicators size and lead block fields side Output factor of lead block fields was related to electron beam energy. Conclusion: Electron beam energy, standard applicator size and lead block fields side had a obvious influence upon output factor. The accurate measurement should be performed for use electron beam energy in the clinic.
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Objective To compare the accuracy of output factor calculation for rectangular inserts of electron beams by using three kinds of algorisms: square root, one dimensional formula and area periphery ration. Methods The differences between the values of output factor calculated by these three algorithms mentioned above and the results measured by ionization chamber for seven rectangular inserts were compared. Results When beam energy was fixed, the difference between calculated and measured output factors was larger for area periphery ration algorithm than that of the square root or one dimensional formula algorithms. The electron cone size, beam energy and rectangular inserts size all had some effect on the value of output factor calculated by the three algorithms. Conclusions The area periphery ration algorithm is not recommended for clinical use because of its great deviation. One dimensional formula and square root algorisms possess a good accuracy. One dimensional formula is superior to square root algorithm, but square root algorithm is more practical for clinical use.