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1.
Journal of Southern Medical University ; (12): 1551-1553, 2013.
Article in Chinese | WPRIM | ID: wpr-232753

ABSTRACT

<p><b>OBJECTIVE</b>To detect serum content of cofilin protein in patients with lung cancer and investigate its clinical value.</p><p><b>METHODS</b>The serum content of cofilin protein was detected in 30 cases of lung cancer and 30 healthy control subjects using enzyme-linked immunosorbent assay.</p><p><b>RESULTS</b>The mean serum content of cofilin protein was 0.485∓0.465 ng/ml in patients with lung cancer and 0.203∓0.102 ng/ml in the control subjects, showing a significant difference between them (P<0.05). The content of cofilin protein in patients with stage III and IV lung cancer 0.744∓0.584 ng/ml, significantly higher than that in stage II patients (0.257∓0.126 ng/ml).</p><p><b>CONCLUSION</b>Serum cofilin protein is elevated in patients with lung cancer, especially in cases in advanced stages, suggesting its relation with lung cancer staging.</p>


Subject(s)
Adult , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Actin Depolymerizing Factors , Blood , Adenocarcinoma , Blood , Diagnosis , Pathology , Carcinoma, Squamous Cell , Blood , Diagnosis , Pathology , Enzyme-Linked Immunosorbent Assay , Lung Neoplasms , Blood , Diagnosis , Pathology , Neoplasm Staging
2.
Chinese Journal of Primary Medicine and Pharmacy ; (12): 2907-2908, 2012.
Article in Chinese | WPRIM | ID: wpr-427889

ABSTRACT

Objective To summarize the clinical experience of thoracic injury.Methods Analyze 778 cases of thoracic injury,including soft tissue injury,rib fracture,hemothorax and pneumothorax,pulmonary contusion,cardiovascular injury,et al.The causes of the injury including traffic accident,injury suffered from the job and dispute,et al.Results 774 cases were cured among all the 778 cases with the recovery rate of 99.35%.There were 5 cases died with the death rate of 0.65%,including 1 case of heart rupture,1 case of large vessle rupture,2 cases of brain combining injury,1 case of spleen combining injury.Conclusion Thoracic injury arise new characteristic in recent years.The main causes of the injury are traffic accident,injury suffered form the job and dispute.Most cases may be cured by rapid treatment.The main causes of death are haemorrage shock due to cardiovascular or spleen rupture and combination of severe brain injury.

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