effect of ubiquinone on functional recovery and morphometric indices of sciatic nerve regeneration

A common cause of peripheral nerve injury is trauma. The positive effect of antioxidants on the improvement of nerve regeneration has currently become a focus of attention. In this experiment, the effect of intraperitoneal administration of ubiquinone [CoQ10] on an acute experimentally sciatic nerve crush was studied in a rat model. Forty-five male Wistar rats, weighing between 160-180 g were used. The rats were randomly divided into two experimental groups [n=20]. Each group was further subdivided into four subgroups of five animals each. Functional studies confirmed the faster recovery of regenerated axons in the treatment group compared to the un-treated group [P<0.05]. Morphometric indices of the regenerated fibers showed the number and diameter of the myelinated fibers to be significantly higher in the treatment group than the un-treated group [P<0.05] Intraperitoneal administration of CoQ10 [10 mg/kg/day] in the early inflammatory stage of sciatic nerve crush was found to improve nerve regeneration

[Comparison of hip abductor, extensor and external rotator strength in women with and without patellofemoral pain syndrome]

Patellofemoral pain syndrome [PFPS] is a common musculoskeletal condition. Women with patellofemoral pain syndrome would present significant weakness in many of hip muscle groups when compared with the healthy group. The objective of the present study was to compare the strength of hip abductor, extensor and external rotator muscle groups in sedentary women with bilateral patellofemoral pain syndrome to a matched control group of sedentary women without patellofemoral pain syndrome. Twelve women with bilateral patellofemoral pain syndrome as experimental, group and other twelve matched women as control group participated in this study. Maximum isometric strength for three hip muscles including abductor, extensor and external rotator muscle groups was measured bilaterally in all subjects using a dynamometer fixed on a platform and finally averaged between two limbs and compared with the control group. The hip abductor, extensor and external rotator muscle groups of experimental group were statistically weaker than that of the control group [p< 0.001]. It seems that lower limb muscles including hip muscles of women with patellofemoral pain syndrome become weaker due to disuse conditions

Retention of creative pin placement vs. traditional method in human mandibular molar teeth [in vitro]

Extensive caries restoration has always been considered as one of dental issues. To resolve this problem different methods have been suggested such as dentinal pins.Previous clinical studies revealed that the use of retentive pins, faces numerous risks [pulp exposure, dentin cracks, root perforations, etc]. Introducing of bonding and composite systems, resulted in minimized mechanical retention for cavity preparation. Advantages of amalgam restorations such as simplicity of use, better mechanical properties, suitable clinical longevity and being less costly sustained its use in practice. On the other hand, caries removal usually results in a cavity form with small undercuts. So if we fill these small undercuts with [Bonding and Composite], then insertion of pins in this base, could be considered as a safe way for obtaining retention. The purpose of this study was comparing the retention of creative pin placement [using composite] to the retention of traditional method. In this experimental study thirty sound human mandibular molar teeth free from decay and restoration were selected. The occlusal surface of samples was removed up to 3mm above CEJ. Teeth were divided in 2 groups: Group A: [N=15] T.M.S Minim pin inserted in dentin at 2mm depth. Group B: [N=15] One layer of composite [1mm] bond to flat occlusal surface of teeth and then the pin was inserted in it at 2mm depth so only 1mm of pin placed into dentin. Group C: [N=15] cylinders of composite were prepared [height=5mm, dimension= 8mm] and pin was inserted in them at 2mm depth. The retention of pins was determined under tensile force with Zwick universal testing machine and data was charted by Test Xpert. 10-11 program. Data were analyzed by variance analysis [ANOVA] and L.S.D test. The ANOVA showed: a statistically significant difference between all groups. [p< 0.05] The L.S.D test showed: - No significant difference between A and B. [p> 0.05] - Significant difference between A, B and C. [p< 0.05]. The highest tensile strength belonged to group A. there was no significant difference between group A and B. So by using this technique 1mm depth of pin in dentin can result as same retention as 2mm depth. The lowest tensile strength belonged to group C

Comparison of direct and indirect composite resin restorations effect on the fracture resistance of maxilly premolars [an in vitro study]

One of the problems involved in the restoration of extensive cavities is loss of the fracture resistance of the remaining tooth structure to withstand masticatory forces. But possible reinforcement of remaining tooth structure has been increased by the use of adhesive restorative materials. Tooth reinforcement may be affected by the different physical properties of direct and indirect composite resin restorations. So, theaim of this study was tocompare direct and indirect composite resin restorations effect on the fracture resistance of maxillary premolars with mesio-occluso distal [MOD] cavities. In this experimental [in vitro] study, 24 human maxillary premolars free of any caries, restoration or crack, which had been extracted in a 6 month period, were selected and MOD cavities with the bucco- lingual extension equal to two third of intercuspal distance were prepared on them all. The teeth were divided randomly in 3 groups including A [8 teeth and direct restoration group], B [8 teeth and indirect restoration group] and C [8 teeth and preparation without restoration group] and were undergone fracture test with universal testing machine. Variance and Tukey tests were used for analysis of results; the level of significance was set at 0.05. The mean fracture resistance was!314.75 +/- 332.26, 1192.25 +/- 352.45 and 382.45 +/- 142.51 for direct restoration, indirect restoration and preparation withoutrestoration groups,respectively. There was no significant difference between A and B groups [P=0.60], whereas the differences were significant between A and C groups [P=0.00] and also B and C groups [P=0.00]. According to the present study, both direct and indirect composite restorations cause increase in the fracture resistance of teeth and so can have an important role in extensive cavities

Evaluating the effects of low intensity pulsed ultrasonic waves on experimental tibial fracture healing in New Zealand rabbit

Fracture healing is a biological complex process that is affected by several internal and external factors. One of the external factors is mechanical stimulation by ultrasound waves. There is a controversy about the effects of these waves on bone healing. The aim of this research was to evaluate effects of low-intensity pulsed ultrasonic waves on experimental tibial fracture in New Zealand Rabbit. This is an experimental study in which, 36 male adult New Zealand rabbits were randomly divided into four groups [3 experimental groups and 1 control group]. All of the animals, except the control group, were operated for inducing the experimental fracture on their right tibia. After healing of wounds, the sites of bone fractures in experimental groups were exposed to pulsed ultrasound waves for 2 and 4 weeks. Then all of the animals were killed and right tibias were removed. After fixation and processing of samples, the slides were prepared from paraffin blocks and were stained with H and E. Finally, the slides were studied for stereological analysis of bone healing and the data of each group was analyzed by Mann-Whitney and Kroscal Wallis tests. The Results of this study showed that mean volume changes in cartilaginous callus was significantly higher in ultrasound- exposed rabbits compared to the control group [P<0.05]. No significant differences was seen between experimental and control groups for other parameters such as granulation, mesenchymal tissue and bone tissue. Pulsed-ultrasound waves with frequency about 1 MHz [Mega Hertz] may be useful to increase fracture healing of tibia in rabbit

[ case report of abdominal pregnancy]

Abdominal pregnancy is a very rare condition of ectopic pregnancy with a high mortality rate for mother and fetus. It occurs when the gestational sac implanted outside the uterus, ovaries and fallopian tubes. Although this condition is potential life-threatening but often misdiagnoses of other variant ectopic pregnancy. Prompt detection in initial stage of pregnancy is necessary to prevention of dangerous complication. This present casereport was a patient who admitted in the Alzahra hospital during two decades. She was a 23-year old nulliparous woman with a history of primary infertility that underwent ovarian hyper stimulation with clomiphen citrate. She underwent transvaginal ultrasonography because of menstrual retardation, positive serum betaHCG test and spotting. It was diagnosed an incomplete abortion according to clinical symptoms and lack of gestational sac inside the uterus. Transvaginal ultrasonography was performed again for persistency the pregnancy symptoms after 4months. Diagnostic pelvic ultrasonography confirmed a 16-week intra-abdominal pregnancy. The ultrasonographic examination confirmed a 27-week intra-abdominal pregnancy. The woman was admitted immediately. The surgery was performed, without any complications. She recovered well and was discharged soon