ABSTRACT
Objective:To establish a method for the determination of Mg and Al in 5-layer co-extrusion bags and their migration from the bags into infusion by ICP-MS. Methods:The samples were digested by microwave digestion, and the contents of Mg and Al were determined by ICP-MS under certain working conditions. Results:Both Mg and Al had a linear range between 2. 5 and 20. 0 μg ·L-1, and r was 0. 999 6 and 0. 999 7, respectively. The average recovery of Mg was 92. 90% (RSD=3. 01%,n=9),and that of Al was 94. 15% (RSD=4. 11%,n=9). Conclusion:The method is accurate, sensitive and simple, and can be used for the determi-nation of Mg and Al in 5-layer co-extrusion bags and their migration from the bags into infusion.
ABSTRACT
Objective:To establish a method for the determination of antioxygen 1178 in 5-layer co-extrusion bags used for infu-sion. Methods:A Uitimat XB-C8 (250 mm × 4. 6 mm,5μm) column was used,the mobile phase was methanol-water with gradient elu-tion, the flow rate was 1. 0 ml·min-1 ,the detection wavelength was 223 nm,the column temperature was 35℃ and the injection vol-ume was 20 μl. Results:The concentration of antioxygen 1178 had the linear relationship within the range of 1. 64-205. 10 μg·ml-1 (r=0. 999 9),and the average recovery was 92. 05% (RSD=1. 94%, n=9). Conclusion:The method is accurate,stable and spe-cific,and can be used to determine antioxygen 1178 in 5-layer co-extrusion bags used for infusion.