A comparative evaluation of visual, refractive, and patient-reported outcomes of three diffractive trifocal intraocular lenses

@#OBJECTIVE: To compare the visual, refractive, and patient-reported outcomes of eyes implanted with one of 3 trifocal intraocular lenses (IOLs). METHODS: This is a cross-sectional, comparative, non-interventional study wherein subjects implanted with FineVision Micro F, AT LISA tri 839MP or AcrySof IQ PanOptix trifocal IOL after phacoemulsification were recruited. Manifest refraction, uncorrected and corrected visual acuity (VA) at distance, intermediate and near vision, contrast sensitivity, modulated transfer function (MTF) values and questionnaire answers were compared among the 3 groups using analysis of variance (ANOVA). RESULTS: Fifty-seven (57) eyes were included in the study: 21 eyes with FineVision (group A), 21 eyes with LISA tri (group B), and 15 eyes with PanOptix IOL (group C). The post-operative mean manifest spherical equivalent was -0.01D, -0.07D, and 0.05D, respectively (p=0.083). Uncorrected distance VA and best-corrected distance VA were similar among the groups. Groups A and C had better uncorrected and corrected intermediate VA at 80 cm and at 60 cm compared to group B. Group A had significantly better uncorrected near visual acuity than groups B and C (p=0.032). Mesopic contrast sensitivity testing showed group C had higher contrast sensitivities without glare in at the spatial frequency of 6 CPD (p=0.038) and with glare at 3 CPD (p=0.039) and at 12 CPD (p=0.009). MTF average height analysis showed that the group A had significantly superior resolution in far targets compared to groups B and C (p=0.001). At near targets, groups A and C had better resolutions compared to group B (p=0.017). There was no significant difference in patient satisfaction for far, intermediate and near VA among the groups. CONCLUSION: Eyes implanted with any of the 3 trifocal IOL designs achieved excellent uncorrected and bestcorrected distance, intermediate and near vision. FineVision and PanOptix provided significantly better intermediate vision than LISA tri at both 80 cm and 60 cm testing distance. FineVision had better near visual outcomes than PanOptix and LISA tri. Patient satisfaction was high in all 3 trifocal IOLS

Clinical observation of multifocal intraocular lens with aspheric astigmatism in cataract surgery / 国际眼科杂志(Guoji Yanke Zazhi)

AIM: By comparing the aspheric and multifocal Toric intraocular lens and the aspheric intraocular lens in cataract patients,to observe the patients` visual quality,to evaluate the patients` distance visual acuity,near visual acuity,Pseudo-accommodative power,residual astigmatism,the rotational stability of AcrySof IQ Toric Restor intraocular lens (IOLs),contrast the rate of off-distance glass,the rate of off-near glass and patient satisfaction after the implantation of AcrySof IQ Toric Restor IOL in the cataract patients with preexisting corneal astigmatism.METHODS:Carried out in 46 patients (48 eyes) with age-rated cataract who receiving phacoemulsification and implantation of artificial lens in our department during February 2014 to June 2016.All the cases were randomly divided into 2 groups: experimental group: 23 cases (24 eyes),AcrySof IQ ReSTOR Toric IOL was implanted after phacoemulsification;control group: 23 cases (24 eyes),AcrySof IQ was implanted.Uncorrected distance visual acuity (UCDVA) and best corrected distance visual acuity (BCDVA),uncorrected near visual acuity (UCNVA) and best-corrected near visual acuity(BCNVA),Pseudo-accommodative power,residual astigmatism,preoperative and postoperative corneal astigmatism,the rate of off-distance glass,the rate of off-near glass and patient satisfaction were measured at 6mo postoperatively follow-up.RESULTS: BCDVA and BCNVA were not statistically different between the two groups(P<0.05).At 1wk,1,3 and 6mo postoperatively of UCDVA the experimental group were statistically better than the control group (P<0.05).UCNVA were also statistically better than the control group (P<0.05).The mean residual astigmatisms 1wk,1,3 and 6mo postoperatively were statistically differences between the control group and experimental group (P<0.05).At 6mo postoperatively,patients satisfaction of experimental group were significantly better than control group (P<0.05).Spectacles independence for near vision achieved 83% and 17% in experimental group and control group,experimental group were statistically better than control group(P<0.05).Spectacles independence for distance vision achieved 92% and 67% in experimental group and control group,experimental group were statistically better than control group(P<0.05).CONCLUSION:The results indicate that AcrySof IQ ReSTOR Toric IOLs may provide a better uncorrected distance visual acuity and uncorrected near visual acuity,which can significantly reduce preexisting corneal astigmatism in cataract surgery,improve spectacles independence for distance vision and spectacles independence for near vision,have a high patient satisfaction.

Early clinical effects of phacoemulsification cataract surgery with implantation of Acrysof IQ Restor multi-focal toric lens / 医学研究生学报

Objective Acrysof IQ Restor multifocal toric intraocular lens ( IOL) is a new product , which allows a single sur-gical procedure for presbyopia correction and corneal astigmatism management .This study was to evaluate the early clinical effects of phacoemulsification cataract surgery with implantation of a diffractive multifocal toric IOL . Methods We retrospectively analyzed 7 cases (9 eyes) of corneal astigmatism ≥1.0 diopter (D) treated by phacoemulsification with implantation of an Acrysof IQ Restor toric IOL.The patients were followed up for 3 months for observation of uncorrected distance visual acuity ( UDVA) , best corrected distance visual acuity ( CDVA) , uncorrected near visual acuity ( UNVA ) , best corrected near visual acuity ( CNVA ) , spherical equivalent (SE) refraction, focal depth, residual astigmatism, rotational stability of the IOL, contrast sensitivity (CS), and spectacle independ-ence preoperatively and at 1 week, 1 month, and 3 months after operation . Results At 3 months after surgery , the UDVA ( log-MAR), CDVA, UNVA, and CNVA were 0.07 ±0.10, 0.02 ±0.11, 0.12 ±0.06, and 0.08 ±0.07, respectively, with an SE re-fraction within ±0.50 D of the attempted spherical correction in 8 eyes (88.9%) and a focal depth of (5.32 ±1.78) D.The residual astigmatism at 3 months was significantly reduced as compared with the baseline ([0.25 ±0.28] vs [1.55 ±0.39] D, P0.05).At 3 months, the mean IOL axis rotation was (3.11 ±1.61)°and CS was remarkably im-proved ( P0.05) except at 18.0 cpd (P<0.05). Conclusion Implantation of the Acrysof IQ Restor multifocal toric IOL provides excellent overall quality of vision, spectacle independence, visual quality, and rotational stability for patients with cataract and corneal astigmatism.

Refractive and visual outcomes of surgical treatments for high myopia

Objective@#To present the refractive and visual outcomes of refractive surgical treatment options in high myopia. @*Methods@#This was a retrospective review of patients diagnosed with high myopia (manifest refractive spherical equivalent [MRSE] ≥-6.00D) who underwent one of the following procedures: laser-in-situ keratomileusis (LASIK), photorefractive keratectomy (PRK), phakic IOL implantation with the Staar Implantable Collamer Lens (ICL), or Alcon Cachet Phakic IOL. Eyes with best corrected distance vision of less than 20/30 due to amblyopia or other eye pathologies were excluded.

AcrySof toric intraocular lens for post-keratoplasty astigmatism.

We report a 63-year-old male who had undergone left eye optical penetrating keratoplasty for central leucomatous corneal opacity 10 years earlier. The eye had clear donor graft with residual astigmatism of –6.50 diopter cylinder (DC) at 30°. The patient underwent clear corneal phacoemulsification with implantation of +6.0 D spherical equivalent AcrySof SN60T9 intraocular lens (IOL). Postoperatively, at 10 months, the patient had distance corrected visual acuity of 20/30 with –2.00 DC at 20°. AcrySof toric IOL offers an effective treatment option for post-keratoplasty high corneal astigmatism in patients with cataract.

The Efficacy of KR-1W Aberrometer in Assessing the Astigmatism after Toric Intraocular Lens Implantation

PURPOSE: To evaluate the efficacy of the KR-1W aberrometer in assessing the astigmatism and the achieved axis after AcrySof Toric intraocular lens (IOL) implantation. METHODS: Thirty-nine patients (48 eyes) that had undergone phacoemulsification and AcrySof Toric IOL implantation were included in the present study. At postoperative 1 month, ocular aberrations of all the eyes were measured using the KR-1W aberrometer before mydriasis and the achieved axis of AcrySof Toric IOL was measured by slit lamp examination after mydriasis. The achieved axis measured by slit lamp examination and the astigmatism of the implanted AcrySof Toric IOL were compared with the KR-1W. RESULTS: The mean achieved lens axis after mydriasis measured by slit lamp examination and KR-1W was 86.43 +/- 47.49 degrees and 88.93 +/- 41.22 degrees, respectively. The correlation coefficient of the 2 methods was 0.992 (p < 0.001). The measured astigmatism according to the AcrySof Toric IOL model was 1.11 +/- 0.47D in SN60T3, 1.71 +/- 0.51D in SN60T4, and 3.32 +/- 0.78D in SN60T5. CONCLUSIONS: Without the need to directly evaluate the axis of implanted Toric IOL after mydriasis, the achieved lens axis can be measured by the KR-1W without mydriasis. The AcrySof Toric IOL model could be assessed by the KR-1W without information about the AcrySof Toric IOL model.

Comparison of Visual Function Between Two Aspheric Intraocular Lenses After Microcoaxial Cataract Surgery

PURPOSE: To compare the visual function and postoperative refraction between two aspheric intraocular lenses (IOLs) after microcoaxial cataract surgery. METHODS: A prospective analysis of 60 eyes of 58 patients who had undergone microcoaxial phacoemulsification and implantation of aspheric IOLs (AcrySof IQ, 30 eyes; Akreos MI60, 30 eyes) was performed. The best corrected visual acuity (BCVA), spherical equivalent, intraocular pressure (IOP), corneal thickness, endothelial cell density (ECD), predictability of postoperative spherical equivalent, higher order aberrations, contrast sensitivity test, satisfaction, and glare were evaluated during the follow-up period of three months. RESULTS: There were no significant differences in BCVA, spherical equivalent, IOP, corneal thickness, or ECD (p>0.05). The predictability of the postoperative spherical equivalent in the AcrySof IQ and Akreos MI60 IOL groups was not significantly different (p=0.59), and the two groups showed good anterior-posterior stability during the postoperative three months. There were no significant differences in higher order aberrations, contrast sensitivity test, satisfaction or glare (p>0.05). CONCLUSIONS: Both AcrySof IQ and Akreos MI60 implantation groups showed similar visual functions and postoperative spherical equivalents after microcoaxial cataract surgery.

Decentration, Tilt and Anterior Chamber Depth: Aspheric vs Spheric Acrylic Intraocular Lens

PURPOSE: To compare the decentration, tilt and anterior chamber depth between aspheric AcrySof(R) IQ IOL (SN60WF) and spheric AcrySof(R) Natural IOL (SN60AT). METHODS: The subjects of this study consisted of 22 patients (26 eyes) using an aspheric AcrySof(R) IQ IOL and 26 patients (31 eyes) using spheric AcrySof(R) Natural IOL. All lenses were inserted into the capsular bag after 5 mm continuous curvilinear capsulorhexis and phacoemulsification. The decentration, tilt and anterior chamber depth of both IOLs were measured on the 1st, 30th and 60th postoperative day using an anterior eye segment analysis system (Scheimpflug camera, EAS-1000, Nidek, Japan). RESULTS: There was no statistically significant difference in the decentration between the IQ IOL and Natural IOL on the 1st (p=0.05), 30th (p=0.09) and 60th (p=0.06) postoperative day. There was a statistically significant difference in tilt between IQ IOL and Natural IOL on the 1st (p=0.000053) and 30th (p=0.018) postoperative day. However, there was no statistically significant difference in tilt on the 60th postoperative day (p=0.05). The anterior chamber depth of IQ IOL was decreased, but was not statistically significant on the 1st (p=0.10), 30th (p=0.07) or 60th (p=0.06) postoperative day. CONCLUSIONS: There were no significant differences between AcrySof(R) IQ IOL and AcrySof(R) Natural IOL in decentration, tilt or anterior chamber depth, showing that posterior aspheric surface causes little effect on the IOL stability.

Ocular Aberrations and Contrast Sensitivity in Eyes Implanted with Aspheric and Spherical Intraocular Lenses

PURPOSE: To compare spherical aberration, higher-order aberration, and contrast sensitivity of eyes implanted with aspheric (AcrySof IQ) or spherical (AcrySof Natural) intraocular lenses. METHOD: Seventy-five eyes implanted with posterior chamber intraocular lenses were divided into two groups: AcrySof IQ (35 eyes) and AcrySof Natural (40 eyes). Wavefront analysis (spherical, higher-order and total aberration) using iTace, and contrast sensitivity (under photopic and mesopic condition) using Optec 6500 were performed at 1 month and 3 months postoperatively. RESULT: One month after surgery, the IQ IOL (intraocular lens) group had lower values of spherical aberration (p<0.001) and higher-order aberration (p=0.048) than the Natural IOL group. The IQ IOL group also showed better contrast sensitivities at 1.5- and 3-cpd spatial frequencies in mesopic conditions. Three months after surgery, the IQ IOL group had less spherical aberration (p<0.001) and higher-order aberration (p=0.027) than the Natural IOL group and showed better contrast sensitivities at the 3-cpd spatial frequency in mesopic conditions. CONCLUSIONS: Aspheric AcrySof IQ IOL induced significantly less higher-order aberration and spherical aberration than AcrySof Natural IOL. The contrast sensitivity was better under mesopic conditions in the AcrySof IQ IOL-implanted group.

Anterior Fibroblastic Proliferation of Lens Epithelial Cells in Acrylic Intraocular Lens

PURPOSE: To report upon two cases of anterior capsule opacification (ACO) proliferating into the pupillary region of the anterior surface of a single piece acrylic AcrySof(R) intraocular lens (IOL) (SA60AT, Alcon Laboratories, Inc., USA). The surgical removal of the ACO was also reported. METHODS: An 80-year-old woman and a 75-year-old woman underwent phacoemulsification with implantation of a single piece foldable AcrySof(R) IOL in the posterior capsular bag. ACO proliferating from the opposite sides of the IOL along the central axis were found three months after surgery. To recover visual acuity in the 80-year-old woman's eye, ACO was surgically removed with a Sinskey hook and irrigation and aspiration system. RESULTS: The patient's visual acuity was recovered after surgical removal of the ACO. Histopathologic findings of the removed tissues revealed fibroblastic proliferation of lens epithelial cells. The ACO in 75-year-old woman's eye was not treated, as it was not associated with a visual disturbance. CONCLUSIONS: In eyes containing an AcrySof(R) IOL, clinically significant ACO proliferation into the pupillary region along the central axis can occur. Surgical removal can be beneficial for recovery of visual acuity.

Comparison of Decentration and Tilt in Foldable Acrylic Intraocular Lenses

PURPOSE: To compare the decentration and tilt between Acrysof(R) Single-piece and Acrysof(R) Multipiece posterior chamber intraocular lenses (PCLs). METHODS: The subjects of this study comprised 14 patients (15 eyes) using an Acrysof(R) Single-piece and 14 patients (15 eyes) using an Acrysof(R) Multipiece. All of these PCLs were inserted into the capsular bag after continuous curvilinear capsulorhexis and phacoemulsification. The decentration and tilt of the Acrysof(R) Single-piece and the Acrysof(R) Multipiece were measured on the 1st, 30th and 60th postoperative day using an anterior eye segment analysis system (EAS-1000, Nidek, Japan). RESULTS: There was no statistically significant difference in decentration between the Acrysof(R) Single-piece and the Acrysof(R) Multipiece PCL on the 1st (P=0.254), 30th (P=0.078), or 60th (P=0.520) postoperative day. Also, there was no statistically significant difference in tilt between the two PCLs on the 1st (P=0.165), 30th (P=0.395), or 60th (P=0.419) postoperative day. CONCLUSIONS: Although the decentration and tilt of the Acrysof(R) Single-piece and the Acrysof(R) Multipiece PCL showed no significant difference after 60 postoperative days, inappropriate insertion into the capsular bag may necessitate more long-term study and follow-up with numerous cases.

The morphological investigation on AcrySof Natural's protective function from acute retinal light injury / 国际眼科杂志(Guoji Yanke Zazhi)

AIM: To investigate whether the Acrysof Natural has the protective function for retina from blue light in morphology.METHODS: Fresh porcine eye cups were formed in vitro. Blue light beam between 420-450nm spectrum eradiated the porcine retina and cultured RPE cells in 30J/cm2 and 40J/cm2, respectively. The adjacent region in 3mm diameter was eradiated in various ways: exposed directly to light, through AcrySof one piece IOL, PMMA IOL,AcrySof Natural IOL, and without light. Then the eye cups were cultured for 48h. Lastly, tissue and cell structure were observed with light microscope and transmission electron microscope (TEM).RESULTS: In the retinal region without light, the structure of every layer was clear, cells in neuroepithelial layer arrayed in rule, some bubble presented in external granular layer and internal granular layer, RPE cells were compact, and the color of pigment article was coincident. In the region with direct blue light and that with 30J/cm2+Acrysof one-piece/ pMMlA, cells on photoreceptor and external granular layer were lost partially, bubble increased, RPE cells were with different sizes, and cell edema, cell lost and pigment article cluster could be seen.. In region with 30J/cm2+Natural, a little disorganization could be seen comparing to that without light, but more normal than those with Acrysof and direct eradia tion. When the power was 40J/cm2, the situation was similar to that with 30J/cm2 but more severe.CONCLUSION: ① the blue light intensity in 30J/cm2 and 40J/cm2 could both induce the acute retinal light injury, ② AcrySof one piece IOL and other PMMA IOLhave no obvious effect no retina comparing to direct eradiation, ③AcrySof Natural can weaken the injury of blue light to some extent.

Sutured Posterior Chamber Intraocular Lens in the Vitrectomized Eye: Comparison of PMMA and Acrysof(R) Foldable Lenses

PURPOSE: To compare the clinical outcomes of scleral fixated posterior chamber intraocular lens in vitrectomized eyes according to IOL types. METHODS: Clinical outcomes of 28 eyes of 28 patients who underwent scleral fixated posterior chamber IOL after pars plana vitrectomy and lensectomy were evaluated according to the IOL type used: 19 eyes with PMMA lens (group 1) and 9 with Acrysof(R) foldable lens (group 2) RESULTS: Postoperative BCVA improved or was stabilized in 7 eyes (36.8%) of group 1, and 7 eyes (77.7%) of group 2 (P=0.04). Mean postoperative change in astigmatism was 1.19 +/- 0.79 diopter in group 1 and 0.62 +/- 0.47 diopter in group 2 (P=0.25). Estimated refractive error was -0.76 +/- 0.26 and -0.74 +/- 0.24 diopter in groups 1 and 2, respectively, and postoperative refractive error was -1.31 +/- 1.27 and -1.23 +/- 1.34 diopter, respectively. This showed a slight myopic shift in both groups. There were postoperative complications such as hyphema in 4 eyes (26.3%) in group 1 and in 1 eye (11.1%) in group 2, and transiently increased IOP in 5 eyes (26.3%) and in 1 eye (11.1%), respectively. The other complications that were found in group 1 were glaucoma, retinal detachment, choroidal detachment, and cystoid macular edema. CONCLUSIONS: Scleral fixation using foldable IOL is thought to be a relevant method in vitrectomized eyes, as it showed less postoperative astigmatism change and complications, and better visual outcome.

Comparison of Decentration and Tilt of Aquasense(R) with Acrysof(R)

PROPOSE: To compare the decentration and tilt between Aquasense(R) and Acrysof(R). METHODS: The subjects of this study were 48 patients (56 eyes) with Aquasense(R) and 44 patients (49 eyes) with Acrysof(R). Each posterior chamber intraocular lens (PCL) was inserted into the capsular bag after continuous curvilinear capsulorhexis and phacoemulsification. The decentration and tilt of Aquasense(R) and Acrysof(R) were measured 1 day, 30 days and 60 days postoperatively using anterior eye segment analysis system (EAS-1000, Nidek, Japan). RESULTS: The decentration showed no difference between Aquasense(R) and Acrysof(R) on 1st (P=0.19), 30th (P=0.07) and 60th (P=0.06) postoperative day. The tilt showed no difference between Aquasense(R) and Acrysof(R) on 1st (P=0.4), 30th (P=0.47) and 60th (P=0.22) postoperative day. CONCLUSIONS: The decentration and tilt of the two intraocular lenses showed no difference on the 60th postoperative day.

Comparison of Decentration and Tilt of Sensar(R) with Acrysof

PURPOSE: To compare the change in the decentration and the tilt of Sensar(R) with Acrysof(R). The optic and haptic portions of the two had a similar composition, but the difference between the two intraocular lens groups was the shape. METHODS: The objects of this study were 59 patients (69 eyes) with Sensar(R) and 44 patients (49 eyes) with Acrysof(R). Each posterior chamber intraocular lens (PCL) was inserted into the capsular bag after continuous curvilinear capsulorhexis and phacoemulsification. The decentration and the tilt of Sensar(R) and Acrysof(R) were measured 1 day, 30 days and 60 days postoperatively using anterior eye segment analysis system (EAS 1000, Nidek, Japan). RESULTS: The decentration of Sensar(R) was significantly lower than that of Acrysof(R) on the 1st and 30th postoperative day but showed no difference on the 60th day. Decentration of Sensar(R) and Acrysof(R) showed no difference on 1st, 30th and 60th postoperative day. CONCLUSIONS: If Sensar(R) and Acrysof(R) are both inserted into the capsular bag adequately, the decentration and the tilt of the two IOLs show no difference on the 60th postoperative day.

The Difference in Post-operative Refractive Error between In-the-bag and Sulcus Intraocular Lens Implantation

PURPOSE: During the cataract surgery, a need to insert IOL into the ciliary sulcus sometimes arises by many intraoperative events. In such case, a change of postoperative refractive error may result due to the change in IOL insertion site. So we evaluated the difference between preoperative expected refractive error and postoperative refractive error in IOL in-the-bag insertion group and in IOL sulcus implantation group and, compared the result in each group. METHOD: We compared the postoperative refractive states between in-the-bag and sulcus IOL implantation group by retrospective review of the 83 patients (96 eyes) who underwent cataract surgery with AcrySof(R) IOL implantation. RESULTS: The mean age of the patients was 58.6 (21~87) years and average follow-up was 9.2 (2~49) months. Seventy three eyes of in-the-bag IOL insertion (Group 1) and 23 eyes of sulcus implantation (Group 2) were studied. The preoperative expected refractive error was -0.31+/-0.43 D, and -0.14+/-0.33 D, and the postoperative manifest refractive error was -0.40+/-0.58 D, and -1.09+/-0.56 D in Group 1 and Group 2, respectively. The difference between this preoperative and postoperative refractory error was not significant in group 1 (p=0.091), but significant myopic shift by -0.95+/-0.46 D was found in Group 2 (p=0.000). There was no difference in postoperative best corrected visual acuity (p=0.106) and incidence of complications between the two groups. CONCLUSION: In case suboptimal posterior capsular or zonular support was noted during cataract surgery, implantation of IOL in the sulcus may be a safe and effective substitution of in-the-bag implantation of IOL. In this case, we should adjust the power of implanting AcrySof(R) IOL to cover the myopic shift of about 1 diopter.

Acrysof(R) and Polymethylmethacrylate Intraocular Lens Implantation in Diabetic Patients

OBJECTIVE: To determine the efficacy of Acrysof(R) intraocular lens (IOL) compared to PMMA IOL about visual acuity & postoperative complications (eg. posterior capsular opacification) in diabetic patients. PATIENTS AND METHODS: We retrospectively reviewed the medical records of 18 patients (21 eyes) which underwent cataract extraction with Acrysof (R) IOL implantation and 58 patients (65 eyes) with PMMA (polymethylmethacrylate) IOL implantation from January 1996 to December 1999 at Chonnam National University Hospital. RESULTS: Postoperative best corrected visual acuity of above or equal to 0.5 was seem in 66.7% in acrysof (R) group, and in 73.9% in PMMA group at 6 months follow-up. Postoperative posterior capsular opacification was 33.3% and 49.2% respectively, and there was statistically significant difference in both group(p=0.021). CONCLUSIONS: Acrysof(R) intraocular lens can be used safely and reduce the rate of posterior capsular opacification in diabetic patients, which can make the positive effect on the treatment of the diabetic retinopathy after cataract surgery.

Clinical Results of Acrysof IOLs and Acryl-C160 IOLs in Complicated Cataracts

PURPOSE: To compare the clinical results of one-piece Acryl IOL C160 (Opthalmed(R), USA) with those of three-piece Acryl IOL AcrySof (MA60BM, Alcon(R), USA) in complicated cataracts. METHODS: In one eye of 30 patients with complicated cataracts, Acryl-C160 IOL was implanted and AcrySof IOL in the other eye. The degrees of anterior capsular fibrosis and posterior capsular opacification together with IOL decentration were evaluated for 12months prospectively. RESULTS: In 9 of 30 eyes with Acryl-C160 IOL, significant fibrosis of anterior capsule was seen as early as 1 month postoperatively. At 12 months, 15 eyes had more than grade 3 of capsular fibrosis. Five eyes had severe contraction of IOL haptic and one eye had significant IOL degradation to be exchanged. On the contrary, 2 of 30 eyes implanted with AcrySof IOL had moderate degree of capsular fibrosis. CONCLUSIONS: In complicated cataracts, Acryl-C160 IOL developed higher incidence of postoperative complications due to the inflammation and poor memory function of IOL haptic. The type and design of IOL haptic together with the function of IOL optic should be considered in selecting the IOLs best fitted in complicated cataracts.

A Clinical Comparison of AcrySof(r) with Hyd rophilic Acrylic IOLs

To evaluate and compare the clinical results of implantation of the AcrySof(r) with Hydrophilic Acrylic IOLs in early postoperative period(to 2 months), we retrospectively analyzed 34patients who had taken clear cornea incision and had been implanted with AcrySof(r)IOL in one eye and Hydrophilic Acrylic IOL in the other eye. There were no stastically significant difference in postoperative best corrected visual acuity, preoperative and postopearative astigmatic changes between AcrySof(r) and Hydrophilic Acrylic IOLs. But, the rates of postoperative capsular fibrosis and contracture of Hydrophilic Acrylic IOL was higher than those of AcrySof(r) IOL as well as postoperative complications. In conclusion, in the degree and rate of after-cataract, AcrySof(r)IOLs are more useful than Hydrophilic Acrylic IOLs. ;therefore, more excellent in long term visual prognosis. Further studies will be needed for the evaluation of clinical safety and efficacy.

Clinical Results in 1000 Cases of Acrysof Intraocular Lens Implantations

To evaluate the clinical results of implantation of Acrysof foldable intraocular lens[IOL], we retrospectively analyzed 814 patients who had been implanted with Acrysof IOLs in their eyes and followed-up over 6months postoperatively. Postoperative conditions such as best corrected visual acuity[BCVA], postoperative complications and capsular fibrosis were evaluated. Postoperative BCVA, with measurement above 0.7 was 83%and above 0.5 was 92%.If there was no ocular pathology, BCVA with measurement above 0.7 was 96.5%.Postoperative complications included 9.8%[80 cases]of posterior capsular opacity, 3.2%[28 cases]of microvacuole, and also anterior capsule contracture, haptic damage.7 cases of posterior capsular opacity[totally 80 cases]required Nd;Yag laser posterior capsulotomy.Capsular fibrosis[61.8%]was divided to 4 grades.Most of them were grade I or IIand above grade was 9.8%. In conclusion, the Acrysof IOL implantation showed good visual outcome and few postoperative complications, especially in PCO, it had excellent results.So, it will show excellent longterm visual prognosis including visual quality.