ABSTRACT
Objective To observe the effects of Bupi-Guhuo decoction in treating astringent Ⅰ,Ⅱ degree of female stress urinary incontinence.Methods 70 Women patients with stress urinary incontinence in outpatient of urology of Xiyuan Hospital of CACMS from December 2012 to October 2011 were randomly divided into a treatment group and a control group,with 35 cases in each group.The treatment group was treated with Bupi-Guhuo decoction,twice daily,1package per time; while the patients in the control group were treated with pelvic floor muscle training therapy.Both groups were treated for 4 weeks.Results The score of ICS-Q-SF and the amount of urinary incontinence comparison:2 weeks after treatment [the treatment group was (6.42～0.79) and (8.85～ 1.07) g respectively; the control group was (6.81～0.91) and (9.35～ 1.23) g respectively].Both groups had obvious improvement than before the treatment [the treatment group (7.73 ～ 1.52) and (12.92 ～2.08) g respectively,the control group was (7.71～ 1.48)and (13.28～2.43) g respectively] (P＜0.01).4 weeks after the treatment [treatment group was(2.68～0.91)and(2.62～1.08) g respectively,the control group was (6.25～0.81) and (8.02～ 1.32)g respectively].Compared with the effects of 2 weeks after treatment,the difference was statistically significant (P＜0.01) in the treatment group,while with no significant change (P＞0.05) in the control group.At the 2 weeks,4 weeks treatment,the effects in the treatment group and the control group had statistical difference (P＜0.05 or 0.01).(②)Clinical curative effect comparison:After treatment,the total effective rate was 67.7％ (21/31) in treatment group and 37.0％ (10/27) in the control group,showing significant difference (P=0.000,P＜0.01).Conclusion Bupi-Guhuo decoction had better therapeutic effects than pelvic floor muscle training in the treatment of female Ⅰ,Ⅱ degree of stress urinary incontinence,also with a time-effect relationship.
ABSTRACT
Objective To investigate the effect of Chinese herbal medicine of astringents on H22 ascitic type hepatoma haematogenous and lymphatic metastasis in mice.Methods In hematogenous metastasis experiment,the growth of lung metas- tasis and hemorheological indexes were observed in Kunming mice after intravenous injection of H22 ascitic type hepatoma into the caudal veins.In lymphatic metastasis experiment,hepatocarcinoma metastasis mice models were established by subcuta- neous injection of H22 hepatocareinoma cells into the right lower limb,and the inhibitory- rate of tumor weight,incidence of metastasis carcinoma in lung,metastasis of lymph nodes were observed.Results In hematogenous metastasis experiment, compared with the model group,the number of metastatic nodules in lung was decreased in Cortex Ailanthi group and Fructus Corni group,and Cortex Ailanthi improved the hemorheological indexes.In lymphatic metastasis experiment,compared with the control group,the number of metastatic nodules in lung was decreased and the inhibitory rate of tumor weight was increased in Fructus Mume group and Fructus Corni group.The metastases of lymph node were decreased in the three astringents groups. Conclusion Chinese herbal medicine of astringents has an inhibitory effect on the metastasis of hepatoma haematogenous and lymphatic metastasis.