ABSTRACT
Background: Gastro - esophageal reflux disease is a common problem in medical practice. There is increasing evidence that GERD causes laryngeal signs and symptoms. AIM: To identify and study the laryngeal manifestations in symptomatic patients with GERD. Methods: A prospective study was conducted in about 60 patients with GERD in a tertiary care medical college hospital for a period of one year. Results: The study was statistically evaluated using chi square test and there was strong statistical significance for the laryngeal manifestations in GERD.Conclusion: The incidence of laryngeal manifestations of GERD in our study was 68%, the common symptom being hoarseness and the common sign being interarytenoid eythema.
ABSTRACT
Objective To investigate the application of the voice acoustic analysis in the evaluation of curative effects of different chronic laryngitis.Methods The adult patients with chronic laryngitis (80 cases)were divided into 3 different syndrome types what were as the Yin deficiency group (28 cases),the Qi deficiency group (25 ca-ses),and the TanNing blood stasis group (27 cases).According to the different compositions of golden voice series medicines,the medicines were administered,combined in two to three.A total of 30 normal people were set to the control group.The German ATMOS voice test and analysis system was used to detect continuous vowel signals and the results were compared before and after treatment.Results Before the treatment,the chronic laryngitis group, compared with control group,had higher jitters,shimmers and NHR.The MPT was significarry shorter and DSI smaller compared with the control group(P 0.05)ex-cept for the parameter-jitter.The jitter,shimmer,and NHR decreased significantly after 1 month treatment while the MPT and DSI increased significantly in the Yin deficiency group and the Qi deficiency group compared with be-fore treatment (P <0.05).There was a statistically significant difference on jitter,shimmer,NHR and DSI and no difference on MPT compared with before treatment in TanNing blood stasis group.Conclusion The voice acoustic a-nalysis could be objective and quantitative to analysis the chronic laryngitis patients'voice quality with different syn-drome types and evaluate the curative effects.
ABSTRACT
La enfermedad por reflujo gastroesofágico (ERGE) es una causa frecuente de consulta en gastroenterología. La ERGE tiene manifestaciones digestivas y extradigestivas. Las manifestaciones extradigestivas que con mayor frecuencia se asocian a ERGE son la tos crónica, laringitis crónica y dolor torácico. La laringitis crónica, definida como la inflamación de la laringe que persiste por más de unas semanas, se asocia de manera frecuente a ERGE en la práctica clínica. Sin embargo, en varios estudios donde se utilizó la monitoría de pH esofágico como herramienta diagnóstica, no se encontró una clara asociación entre laringitis crónica y reflujo. Además, estudios en los que se manejaron inhibidores de bomba de protones en pacientes con sospecha de laringitis crónica por reflujo, mostraron una alta tasa de fracaso terapéutico, ya que en la gran mayoría de los casos, los síntomas persistían a pesar de una adecuada inhibición de la secreción ácida. Consideramos que aunque la ERGE puede ser la responsable de algunos episodios de laringitis crónica, no es la enfermedad que está asociada con mayor frecuencia, y en muchos de los casos en los que se ha descartado razonablemente la ERGE como responsable de los síntomas, deben investigarse de manera exhaustiva otras causas.
Gastroesophageal reflux disease (GERD) is a frequent cause of consultations with gastroenterologists. Extra-digestive symptoms such as chronic coughing, laryngitis and chest pain are frequently associated with GERD. Chronic laryngitis is one of the symptoms most often associated with GERD, yet various studies which have used monitoring esophageal pH as a diagnostic tool have not found any clear association between chronic laryngitis and reflux. Moreover, studies which have treated patients suspected of having chronic laryngitis caused by reflux with proton pump inhibitors (PPIs) have had had rates of therapeutic failures. Symptoms continue to persist in these patients despite adequate inhibition of acid secretion. To date, no evidence exists of the association between chronic laryngitis and GERD, much less evidence of a causal relation. We consider that, although GERD may be responsible for some episodes of chronic laryngitis, it is not the illness most frequently associated with it, and in the many cases in which GERD has been reasonably ruled out, other potential causes must be investigated.