Configurações explicativas do desenvolvimento da resiliência nas redes de suprimentos da administração pública / Ámbitos explicativos del desarrollo de la resiliencia en las redes de abastecimiento de las administraciones públicas / Explanatory settings of the development of resilience in public administration supply networks

Resumo O capital social é uma lente teórica importante para explicar os relacionamentos interorganizacionais e a construção da resiliência nas redes de suprimentos. Para corroborar essa perspectiva, este estudo visa identificar quais atributos do capital social contribuem para explicar o desenvolvimento da resiliência nas redes de suprimentos da administração pública e de que forma eles se combinam nessa explicação. Para tanto, foi realizada uma pesquisa qualitativa e descritiva que utilizou entrevistas com a técnica da grade de repertório para a coleta de dados. Os dados foram analisados mediante a análise de conteúdo de Honey e a análise de coincidência (CNA). Os resultados da pesquisa indicam que o capital social se mostrou fundamental para desenvolver resiliência nas redes de suprimentos na administração pública, por meio dos atributos de compartilhamento de informações técnicas; precisão na comunicação; antecipação na comunicação de informações relevantes; reciprocidade; confiança; transparência e comprometimento. A originalidade do estudo reside na utilização da teoria do capital social em estudos sobre resiliência na administração pública e na adoção de um método de coleta e análise de dados robusto e ainda não explorado em pesquisas na administração pública brasileira. As principais contribuições do estudo foram: 1) destacar o capital social como constructo multinível que influencia o desenvolvimento da resiliência; 2) ampliar os estudos sobre resiliência na administração pública; 3) fornecer informações que podem ser utilizadas por gestores públicos, a fim de evitar ou minimizar a ocorrência de riscos que comprometam a prestação de serviços públicos e 4) adotar um método de pesquisa inédito na administração pública brasileira.

Resumen El capital social es una lente teórica importante para explicar las relaciones entre organizaciones y desarrollar la resiliencia en las redes de suministro. Corroborando esta perspectiva, este estudio tiene como objetivo identificar qué atributos del capital social contribuyen a explicar el desarrollo de la resiliencia en las redes de suministro de la administración pública y cómo se combinan en esta explicación. Se realizó una investigación cualitativa y descriptiva, utilizando entrevistas con la técnica de rejilla de repertorio para la recolección de datos. Los datos se analizaron utilizando el análisis de contenido de Honey y el análisis de coincidencia (CNA). Los resultados de la investigación indican que el capital social demostró ser fundamental para desarrollar resiliencia en las redes de abastecimiento de la administración pública, a través de los atributos de compartición de información técnica, precisión en la comunicación, anticipación en la comunicación de información relevante, reciprocidad, confianza, transparencia y compromiso. La originalidad del estudio radica en el uso de la teoría del capital social en estudios sobre resiliencia en la administración pública y en la adopción de un método robusto de recopilación y análisis de datos que aún no ha sido explorado en investigaciones en la administración pública brasileña. Las principales contribuciones del estudio fueron: (1) resaltar el capital social como un constructo multinivel que influye en el desarrollo de la resiliencia, (2) ampliar los estudios sobre resiliencia en la administración pública, (3) proporcionar información que pueda ser utilizada por los administradores para evitar o minimizar la ocurrencia de riesgos que comprometan la prestación de los servicios públicos y (4) adoptar un método de investigación inédito en la administración pública brasileña.

Abstract Social capital is an important theoretical lens for explaining interorganizational relationships and building resilience in supply networks. This study corroborates this perspective, aiming to identify which attributes of social capital contribute to explaining the development of resilience in public administration supply networks and how they combine in this explanation. A qualitative and descriptive research was carried out, using interviews with the repertoire grid technique for data collection. Data were analyzed using Honey's content analysis and coincidence analysis (CNA). The research results indicate that social capital proved to be fundamental to developing resilience in supply networks in public administration, through the attributes of sharing technical information, precision in communication, anticipation in communicating relevant information, reciprocity, trust, transparency, and commitment. The originality of the study lies in the use of social capital theory in studies on resilience in public administration and in the adoption of a robust data collection and analysis method that has not yet been explored in research in Brazilian public administration. The main contributions of the study were: (1) to highlight social capital as a multilevel construct that influences the development of resilience, (2) to expand studies on resilience in public administration, (3) to provide information that public managers can use to avoid or minimize the risks that jeopardize the provision of public services, and (4) to adopt an unprecedented research method in the Brazilian public administration.

Prevalence, coincidence and distribution patterns of sesamoid bones of the hand / Patrones de prevalencia, coincidencia y distribución de los huesos sesamoideos de la mano

SUMMARY: The aim of this study is to identify the prevalence and distribution patterns of sesamoid bones at the metacarpophalangeal (MCP) and interphalangeal (IP) joints and to determine if there is an association between the distribution patterns and age, gender, and hand side. Patients who had a direct radiograph of the hand obtained between 2019-2020 were retrospectively evaluated. All radiographs were evaluated in terms of the prevalence, coincidence, and distribution patterns of sesamoid bones. Presence of an association between distribution patterns and age, sex and side was also assessed. A total of 1501 hand radiographs were included into the study. There were 12 different patterns of sesamoid bone distribution. The most common distribution pattern was the presence of sesamoid bone at the first MCP joint only (25.8 %). There was a positive correlation between the second and third MCP, second and fifth MCP, second and first IP, third and fourth MCP and fifth MCP and first IP joints. The pattern with a sesamoid bone at the first MCP joint only was more prevalent among males, whereas the pattern involving coincidence of sesamoid bones at the first, second, fifth MCP and first IP joints was more prevalent among females (p<0.001, p=0.031). A positive correlation was observed between age and the number of MCP joints with sesamoid bones (p<0.001). The number of MCP joints with sesamoid bones was found to be higher in females (p<0.001). This study is important in that it provided anatomical data that can be guiding for clinicians in terms of diagnosis and management of hand disorders.

RESUMEN: El objetivo de este estudio fue identificar la prevalencia y los patrones de distribución de los huesos sesamoideos en las articulaciones metacarpofalángicas (MCF) e interfalángicas (IF) y determinar si existe una asociación entre los patrones de distribución y la edad, el sexo y el lado de la mano; fueron evaluadas retrospectivamente radiografías de la mano obtenidas en 2019- 2020. Todas las radiografías se evaluaron en términos de prevalencia, coincidencia y patrones de distribución de los huesos sesamoideos. También se evaluó la presencia de una asociación entre los patrones de distribución y la edad, el sexo y el lado. Se incluyeron en el estudio un total de 1501 radiografías de mano. Se observaron 12 patrones diferentes de distribución de los huesos sesamoideos. El patrón de distribución más común fue la presencia de hueso sesamoideo solo en la primera articulación MCF (25,8 %). Hubo una correlación positiva entre la segunda y la tercera MCF, la segunda y la quinta MCP, la segunda y la primera IF, la tercera y cuarta MCF y la quinta MCF y las primeras articulaciones IF. El patrón con un hueso sesamoideo en la primera articulación MCF fue más prevalente entre los hombres, mientras que el patrón de coincidencia de los huesos sesamoideos en la primera, segunda, quinta articulación MCF y la primera articulación IF fue más prevalente entre las mujeres (p <0.001, p = 0,031). Se observó una correlación positiva entre la edad y el número de articulaciones MCF con huesos sesamoideos (p <0,001). El número de articulaciones MCF con huesos sesamoideos era mayor en las mujeres (p <0,001). Este estudio es importante debido a que proporcionó datos anatómicos que pueden ser una guía para los médicos en el diagnóstico y tratamiento de los trastornos de la mano.

Analysis of animal models of heart failure based on characteristics of clinical symptoms of traditional Chinese and Western medicine / 中国中药杂志

The incidence of heart failure has increased year by year, with a negative impact on quality of life and life expectancy of patients. Reproduction of animal models that meet the characteristics of clinical symptoms is a prerequisite for conducting experimental studies relating to heart failure. Based on the characteristics of clinical symptoms of heart failure in traditional Chinese medicine(TCM) and Western medicine, the existing common animal models of heart failure were explored, and the clinical anastomosis of the existing animal models was analyzed based on the clinical diagnostic criteria of heart failure in TCM and Western medicine. After analysis and comparison, it can be seen that the existing modeling methods are mostly single-factor animal models, with certain gaps between the characteristics of clinical multi-factors and interactions that jointly lead to heart failure, and the modeling methods were mostly guided by Western medicine, with a lack of TCM pathogenic factors in the model process, which is different from the clinical diagnostic criteria of Chinese and Western medicine for heart failure. In terms of syndrome differentiation, heart failure is classified into heart and lung Qi deficiency syndrome, Qi and Yin deficiency syndrome, heart and kidney Yang deficiency syndrome, Qi deficiency and blood stasis syndrome, Yang deficiency and water flooding syndrome, phlegm-drinking obstructive lung syndrome, Yin and yang exhausted syndrome. The existing animal models mostly confused them, with no effective and recognized method for modeling at present. There are major limitations in studies of Chinese medicine. Therefore, based on clinical characteristics of heart failure in Chinese and Western medicine, this article analyzed the existing animal models, defined their advantages and disadvantages and application prospects, and then suggested further improving the corresponding animal models of heart failure and standardizing the model evaluation, so as to improve the clinical coincidence between animal models and Chinese and Western medicine, make heart failure animal models better serve scientific studies, and promote relevant mechanism studies, pathological change studies and drug screening.

A comparative analysis of the Omaha system applied to the nursing description of patients with coronary heart disease / 中国实用护理杂志

Objective@#To explore the feasibility of applying Omaha system theory to patients with coronary heart disease (CHD) through comparative analysis of nursing description.@*Methods@#Using content extraction analysis method, the nursing records, nursing plans and nursing measures of discharged patients with CHD were retrieved from the medical records, and then the conceptual consistency of the extracted records and the problem classification system and intervention measures in the Omaha system were evaluated by cross mapping method.@*Results@#A total of 2 609 nursing problems and intervention measures were extracted from the medical records of 68 patients with CHD. Among them, 1 844 (70.68%) records were labeled as "perfect fit", 608 records (23.30%) as "partial fit", and 157 (6.02%) recordsas "not fit at all". The total fit rate was 93.98% (perfect fit and partial fit). The most frequently reported problems were in physiological domain, followed by health-related behaviors domain, psychosocial domain and environmental domain. The nursing interventions extracted accounted for 26.67% (1 968 sentences) of directions and l00.00% (4 kinds) of categories in the intervention scheme of Omaha system.@*Conclusions@#The conceptual congruence between the medical records of patients with CHD and the Omaha System is quite high. It can help to improve nursing problems of patients of CHD in health-related behavioral domain, psychosocial domain and environmental domain, and can be applied to such patients after appropriate adjustment, so as to help clinical nursing staff to provide specialized and all-round guidance for patients with CHD.

A comparative analysis of the Omaha system applied to the nursing description of patients with coronary heart disease / 中国实用护理杂志

Objective To explore the feasibility of applying Omaha system theory to patients with coronary heart disease (CHD) through comparative analysis of nursing description. Methods Using content extraction analysis method, the nursing records, nursing plans and nursing measures of discharged patients with CHD were retrieved from the medical records, and then the conceptual consistency of the extracted records and the problem classification system and intervention measures in the Omaha system were evaluated by cross mapping method. Results A total of 2 609 nursing problems and intervention measures were extracted from the medical records of 68 patients with CHD. Among them, 1 844 (70.68%) records were labeled as "perfect fit", 608 records (23.30% ) as "partial fit", and 157 (6.02% ) recordsas"not fit at all". The total fit rate was 93.98% (perfect fit and partial fit). The most frequently reported problems were in physiological domain, followed by health-related behaviors domain, psychosocial domain and environmental domain. The nursing interventions extracted accounted for 26.67% (1 968 sentences) of directions and l00.00% (4 kinds) of categories in the intervention scheme of Omaha system. Conclusions The conceptual congruence between the medical records of patients with CHD and the Omaha System is quite high. It can help to improve nursing problems of patients of CHD in health-related behavioral domain, psychosocial domain and environmental domain, and can be applied to such patients after appropriate adjustment, so as to help clinical nursing staff to provide specialized and all-round guidance for patients with CHD.

Motor learning in post stroke subjects: the effects of practice conditions on the temporal synchronization

Abstract AIMS The aim of this study was to investigate the effects of practice schedule on the motor learning of a synchronization timing task in post-stroke subjects. Subjects and METHODS Seventeen post-stroke individuals were assigned to the experimental group and for the control group were selected seventeen healthy individuals. At the acquisition phase, all participants performed 30 trials of a coincident timing task. Nine individuals from each group practiced constantly and eight from each group practiced randomly, with speed changes in the task. Subsequent phases included: 1) immediate transfer test and 2) long term transfer test after 3 days. Data were analyzed in relation to absolute, variable, and constant errors to assess the performance concerning accuracy, consistence, and direction of responses, respectively. RESULTS All groups increased their accuracy through the practice and were able to adapt it in different speeds. The stroke subjects were more variable in their motor responses. There was no effect of the practice schedule on motor learning, regardless the presence or absence of the neurologic damage. CONCLUSION Post stroke individuals were able to learn a synchronizing task and the capacity of adapt their performance after speed perturbation was preserved. There was no effect of the practice schedule on motor learning.

Prevalencia de los factores asociados a la no coincidencia del método de planificación familiar electo en la atención prenatal y el aplicado post-evento obstétrico / Prevalence of the factors associated with the non-coincidence of the method of elected family planning in prenatal care and applied post-event obstetric

RESUMEN Marco teórico: La atención prenatal tiene varios objetivos y entre ellos está el fomentar y sentar bases para una decisión adecuada sobre planificación familiar con base en las condiciones clínicas de la mujer. Es frecuente encontrar en la atención de puerperio que la paciente no haya recibido un método de planificación familiar por distintos factores. Objetivo: Identificar la prevalencia de los factores asociados a la no coincidencia del método de planificación familiar electo en la atención prenatal y el aplicado post-evento obstétrico. Metodología: Diseño transversal descriptivo en pacientes en puerperio inmediato cuyo método de planificación familiar solicitado en consentimiento informado firmado en la atención prenatal no coincidió con el aplicado post-evento obstétrico. Se midieron factores intrínsecos y extrínsecos Resultados: El factor intrínseco más importante fue el cambio de decisión personal 59.0% (IC 95%; 53.10-64.90) y el factor extrínseco la falta de insumos en el 31.20% (IC 95%; 25.60-36.80). Cuando se realizó la evaluación conjunta la prevalencia del cambio de decisión personal se modificó a 35.20% (IC 95%; 29.4-41.0) y la falta de insumos a 12.6% (IC95%; 8.6-16.6) Conclusión: Los factores intrínsecos y extrínsecos asociados a la no coincidencia del método de planificación familiar con mayor prevalencia son el cambio de decisión por la paciente y la falta de insumos respectivamente.

ABSTRACT Background: Prenatal care has several objectives and among them is to promote and lay the groundwork for an adequate decision on family planning based on the clinical conditions of women. It is common to find in puerperium care that the patient has not received a family planning method due to different factors. Objective: To identify the prevalence of the factors associated with the non-coincidence of the method of family planning elected in prenatal care and the post-obstetric event applied. Methods: Descriptive cross-sectional design in patients in the immediate puerperium whose family planning method requested in signed informed consent in prenatal care did not coincide with the applied post-obstetric event. Intrinsic and extrinsic factors were measured Results: The most important intrinsic factor was the change of personal decision 59.0% (95% CI, 53.10-64.90) and the extrinsic factor the lack of inputs in 31.20% (95% CI, 25.60-36.80). When the joint evaluation was carried out, the prevalence of the personal decision change was modified to 35.20% (95% CI, 29.4-41.0) and the lack of inputs to 12.6% (95% CI, 8.6-16.6). Conclusion: The intrinsic and extrinsic factors associated with the non-coincidence of the family planning method with the highest prevalence are the change of decision by the patient and the lack of inputs, respectively.

Limitations of endoscopic ultrasonography in diagnosis of gastric submucosal tumors / 中国内镜杂志

Objective To evaluate endoscopic ultrasonography (EUS) in diagnosis of gastric submucosal tumors (SMTs), and analyze the characteristics of gastric SMTs under EUS. Methods Clinical data of 614 patients with gastric SMTs, who were evaluated by EUS and underwent endoscopic submucosal dissection (ESD) from September 2008 to December 2016, were retrospectively analyzed. The golden standard for lession origins was the intraoperative diagnosis of ESD, and that for pathological types was the combination of postoperative pathological and immunohistochemical findings. The consistency of diagnosis of EUS was evaluated, and the characteristics of lesions under EUS were analyzed. Results The total consistency in diagnosing lesion origins was 91.25％ between EUS and intraoperative results of ESD, and the consistency in diagnosing lesion originated from the muscularis mucosa, submucosa and muscularis propria was 66.67％, 80.85％ and 94.50％, respectively. The total consistency in pathological types was 65.99％ between EUS and postoperative pathological results, and the consistency of gastrointestinal stromal tumor (GIST), leiomyoma, ectopic pancreas and lipoma was 91.85％, 18.56％, 79.76％ and 90.70％, respectively. Conclusion EUS can initially determine the origins and types of gastric SMTs, providing a more accurate basis for endoscopic treatment, but there were some limitations on the diagnosis of leiomyoma and some rare lesions such as hamartoma, inflammatory fibrous polyps, carcinoid, fibroma, etc. Thus, if necessary, the lesion should be removed so as to make a definite diagnosis and prevent malignant change.

Management and practice of intra-laboratory Turn-Around-Time in emergency testing laboratory / 国际检验医学杂志

Objective To master the actual work efficiency situation of emergency inspection,analyze the existing problems,and provide objective basis for continuous improvement through the statistic analysis of intra-laboratory turn-around time (TAT) median,coincidence rate of inspection report within the specified time limit,report timeout reasons and other indexes of different items of emergency inspection group in 2015.Methods All kinds of original data from the different items of emergency inspection groupswere derived from LIS system,according to the different types of projects in different segments.Microsoft Excel2003 software was used to count the actual TAT time of various items,and function was used to calculate TAT median;The non-conformance rate (inspection report timeout rate) and coincidence rate within the prescribed time limit by inspection report were calculated,and gather the statistical analysis on the timeout reasons of daily recorded report.Results With the exception of electrochemical luminescence class,the TAT of other items decreased in different degrees of emergency inspection group in 2015 when compared with 2014.The average coincidence rate of inspection report of various items within the time limit was 94.8%,non-conformance rate of inspection report of prescribed time limit was 5.2%.The top four inspection timeout reasons of various items were more number of submitted samples(59.6%),redo the reinspection (12.4%),smear reinspection (12.0%) and equipment failure (10.0%) in turn.Conclusion The time limit of the emergency report meets the specified requirements and statistical analysis of the causes of overtime can find out the problems and take appropriate measures to provide an objective basis for continuous improvement.

Performance evaluation of the chemiluminescence immunoassay for mycoplasma pneumonia antibody detecting / 中华检验医学杂志

Objective Assessing the detection performance of testing mycoplasma pneumonia(MP) type-specific antibodies by Chemiluminescence immunoassay(CLIA), in order to evaluate the feasibility of screening MP infection by CLIA.Methods Total of 280 cases of respiratory disease patients,20 examples infected mycoplasma pneumonia and 20 cases health volunteers as the control group were enrolled in this study from August 2016 to October 2017 in the Nanfang Hospital,Southern Medical University,testing MP antibodies by CLIA,Enzyme linked immunosorbent assay(ELISA)and Passive agglutination method(PA) respectively.According to the performance evaluation scheme, we evaluate the performance indexs of detecting MP antibodies by CLIA, including lower limit of detection, intra-batch precision, inter-batch precision,linearity range,clinical coincidence rate and consistency compared with ELISA and PA,and the results were analyzed by EXCEL and SPSS version 22.0.Results MP-IgG CLIA reagent:Limit of blank, Limit of detection and Limit of quantitation were 1.9 AU/ml,4.5 AU/ml and 5.1 AU/ml respectively;Coefficient Variation(CV)of intra-batch precision in high and low concentration levels were 2.98% and 2.45%respectively; CV of inter-batch precision in high and low concentration levels were 6.44% and 6.83% respectively;both the Linear range and Clinical report range are from 2.0 AU/ml to 253.0 AU/ml;the linear regression equation R 2≥0.990 0,0.85≤b≤1.15.MP-IgM CLIA reagent: CV of intra-batch precision in high and low concentration levels were 2.55% and 2.86% respectively; CV of inter-batch precision in high and low concentration levels were 4.82% and 5.46% respectively.The total clinical coincidence rate of MP-IgG and MP-IgM detected by CLIA were 90.0%and 97.5%respectively.The kappa values of MP-IgG and MP-IgM detected by CLIA and ELISA were 0.763(P=0.000)and 0.804(P=0.023)respectively, with Consistent percentage of 88.9% and 91.4% respectively.The kappa value of CLIA and PA was 0.541(P=0.063)with a consistent percentage of 79.6%.Conclusions The results of study show that detecting MP type-specific antibodies by CLIA meet the prescribed performance indexes. Detecting MP type-specific antibodies by CLIA,which is precise, speedy and automated, could be applied to clinical and replace ELISA and PA, becoming the prior choice in clinical for MP infection screening.

A realidade indistinguível / The indistinguishable reality / La realidad indistinguible

Os problemas psicanalíticos mais comuns requerem, não raro, os mais inusuais processos de demonstração. Este texto deve ser lido como uma ficção teórica, bem assim as pessoas, locais, situações, entidades e teorias mencionados, em que qualquer semelhança com figuras reais será mera coincidência, a menos que não o seja. De mais a mais, coincidência é quando duas realidades se encontram de maneira indistinguível.

The most common psychoanalytic issues often require the most unusual demonstration processes. This paper as well as the mentioned people, places, situations, entities, and theories should be read as a theoretic fiction, in which any resemblance to actual figures is purely coincidental, except if it is not. Moreover, coincidence happens when two realities meet each other in an indistinguishable way.

Los problemas psicoanalíticos más comunes requieren, a menudo, los procesos de demostración más inusuales. Este texto debe ser leído como una ficción teórica, así como las personas, locales, situaciones, entidades y teorías mencionados, en los que cualquier semejanza con figuras reales será una mera coincidencia, a menos que no lo sea. Por otra parte, coincidencia es cuando dos realidades se encuentran de manera indistinguible.

Investigation on Strengthening the Supervision of Drug Stocktaking in Our Hospital / 中国药房

OBJECTIVE:To strengthen the supervision of drug stocktaking,and to improve drug management. METHODS:The data of drug stocktaking were extracted from our hospital from 2011 to 2014,and was analyzed in respects of accounts coinci-dence rate,drug profit and loss account rate,the entry and exit account between departments and original record,etc. A series of supervision strategies were established,and the data of drug stocktaking was analyzed during Jan.-Jun. in 2015 statistically to evalu-ated supervision effects. RESULTS:The supervision of drug stocktaking was strengthened through limiting the right of drug profit and loss on stocktaking,strengthening original stocktaking record management,establishing Key Drug List,setting up drug stock-taking supervision institutions,etc. During Jan.-Jun. in 2015,there was obvious improvement in the drug supervision skills,in terms of account coincidence rate,profit and loss account,material safety,cash flow rate,staff responsibility and stocktaking dura-tion,etc. More specially,the accounts coincidence rate had rose from about 82.8% to more than 95%;both the key drug accounts coincidence rate and the entry and exit account between departments coincidence rate had reached to 100%;the profit and loss ac-count rate had reduced from about 7.6% to less than 0.3%;the stocktaking time had reduced from 10 h to 3 h. CONCLUSIONS:Strengthening drug stocktaking supervision can not only improve the stocktaking efficiency and quality markedly,but also contrib-utes to the development of other pharmacy work in hospital.

Dual-phase18F-FDG coincidence detection SPECT/CT imaging for differential diagnosis of pulmonary lesions / 中国癌症杂志

Background and purpose:Although FDG tumor imaging has been applied in clinic widely, dual-phase imaging can provide much more information about the FDG uptaking of pulmonary lesions. The purpose of the study was to evaluate the usefulness of dual-phase18F-FDG coincidence detection SPECT/CT imaging in the differential diagnosis of the pulmonary lesions.Methods:There were 28 patients with pulmonary lesions which were detected by CT. All the patients undertook the SPECT/CT imaging at 2 time-phases respectively: early imaging at 40-60 min and delayed imaging at 2-3 h after the intravenous injection of FDG. Data processing: calculating the radio of T and N in early and delayed imaging respectively; T: The radioactive count of the lesions; N: The radioactive count of the normal tissue; and the change rate:ΔT/N. ROC was used to ifnd out the threshold of T1/N1, T2/N2及ΔT/N in the differential diagnosis between benign and malignant lesions. AUC was used to evaluate the diagnosis value of the dual-phase and single-phase imaging.Results:The threshold of T1/N1 in early imaging was 2.65, whereas AUC was 0.767. The sensitivity, speciifcity and accuracy were 83.3%, 30% and 64.3%, respectively. The threshold of T2/N2 in delayed imaging was 3.14, whereas AUC was 0.847. The sensitivity, speciifcity and accuracy were 94.4%, 60.0% and 82.1%, respectively. The threshold ofΔT/N in delayed imaging was 16.9%, whereas AUC is 0.950. The sensitivity, speciifcity and accuracy were 88.5%, 71.4% and 86.2%, respectively.Conclusion:Dual-phase18F-FDG coincidence detection SPECT/CT imaging has much higher accuracy and speciifcity. However it still has false positivity, and should be analyzed with CT and clinical history.

Image characteristics of chest schwannoma in coincidence 18F-FDG SPECT studies / 中华核医学与分子影像杂志

Objective To analyze the image characteristics of chest schwannoma in coincidence 18FFDG SPECT studies,and to evaluate its prospective diagnostic function on chest schwannoma.Methods Four cases confirmed as schwannoma by surgery and pathology were enrolled in this retrospective study.Enhanced CT and coincidence 18F-FDG SPECT studies were performed before surgery.Imaging characteristics for the diagnosis of chest schwannoma were summarized.Results Tumors were totally removed by surgery.The histological diagnosis of schwannoma was confirmed by pathological,HE and immunohistological staining examination (positivity for the S-100 protein and vimentin),including 1 case of malignant schwannoma and 3 cases of benign.Four cases all showed high uptake of 18F-FDG.The uptake in malignant schwannoma was much higher than that in benign schwannoma.Benign schwannomas were noninvasive masses and mainly showed compression symptoms,with obvious lobulation and distinct borders.Malignant schwannoma was invasive masses.Conclusions 18 F-FDG coincidence SPECT is of limited value as a prospective diagnostic imaging technique for the identification of benign schwannoma from malignant schwannoma.But it could play an important role in the staging,restaging,and post-therapy follow-up of schwannoma.

Coincidence rates between empiric antimicrobial use and antimicrobial sus-ceptibility testing results in patients with pyelonephritis / 中国感染控制杂志

Objective To understand the empiric antimicrobial use in patients with pyelonephritis in a hospital,and pro-vide reference for clinical rational antimicrobial use.Methods Data of 620 patients with pyelonephritis admitted to the nephrology department of a hospital between January 2011 and September 2014 were collected,application of antimicrobial agents,coincidence between empiric antimicrobial use and antimicrobial susceptibility testing results in patients with different diseases and different ages were analyzed.Results Before antimicrobial susceptibility testing results were reported,620 pa-tients use 625 times of antimicrobial agents,5 of whom used two kinds of antimicrobial agents at the same time,8 varieties in 15 types of antimicrobial agents were involved,the most frequently used antimicrobial agents were third generation ceph-alosporins,cephamycins,and fluoroquinolones.The overall,partial,and non-coincidence rate between antimicrobial use and antimicrobial susceptibility testing results were 64.32%(n=402),8.32%(n=52),and 27.36%(n=171)respective-ly.The overall coincidence rate in patients with acute pyelonephritis was higher than those with chronic pyelonephritis (77.61% [n=357]vs 58.79%[n=97],P <0.05).The overall coincidence rate in patients <50 years old and ≥50 years old were 68.12%(156/229)and 75.25%(298/396)respectively,there was no significant different between two groups (χ2 =2.93,P =0.09).Conclusion The non-coincidence rate between empiric antimicrobial use and antimicrobial suscepti-bility testing results is high,measures needs to be taken to improve the empiric antimicrobials use.

The target/no target ratio analysis of 18F-FDG uptaking in head and neck malignancy by SPECT/CT coincidence imaging / 天津医药

Objective To investigate the influencing factors of 18F-FDG uptaking in head and neck malignancy by SPECT/CT coincidence imaging. Methods 18F-FDG SPECT/CT coincidence imaging was performed in 32 patients with head and neck malignancy after surgery, radiotherapy or radiotherapy + chemotherapy. The radio of target/no target (T/N) was calculated. The gender, age, fasting blood glucose level, size of tumor, location of tumor, pathological classification, de-gree of cell differentiation and treatment modalities were analyzed between groups. Results The single-factor analysis of variance showed that the T/N value was significantly higher in >70 yeas old, group than that of 41-50 yeas old group and 51-60 yeas old group (P5 cm group (P0.05). The multiple linear regression analysis showed that 18F-FDG uptaking in head and neck malignancy (T/N=Y) was related to the age of patients (X2), the diameter of tumor (X4) and the degree of cell differentiation (X9): =-4.389 25+0.053 03 X2+1.617 86 X4+0.718 35 X9. Conclusion Tumor recurrence is more likely to occur in patients with age>70 years old, the diameter of tumor≥2 cm, and the anaplastic head and neck malignancy.We should pay much attention to the diagnosis and follow-up for these pa-tients.

Analysis on the feasibility of genechip method in detecting Mycobacterium tuberculosis drug resistance / 国际检验医学杂志

Objective To analyse the sensitivity ,specificity and coincidence rate of genechip method in the detection of resistance to antibacterial agents in Mycobacterium tuberculosis(MTB) ,in order to provide a convenient ,accurate and rapid method for detec‐ting antibacterial resistance in MTB .Methods The DNA sequencing was taken as gold standard ,and antibacterial resistance of the strains of MTB isolated from sputum specimens of 250 cases of patients with tuberculosis from August to December 2014 were de‐tected by using the genechip method and proportion method for susceptibility testing at the same time .Efficacies of the two methods in detecting MTB resistance to rifarnpin and isoniazid were compared .Results The MTB resistance rate to rifarnpin detected by u‐sing the genechip method and proportion method for susceptibility testing was 3 .0% and 3 .5% respectively ;that to isoniazid was 6 .7% and 8 .2% respectively .For detecting M TB resistance to rifarnpin and isoniazid ,the DNA sequencing was taken as gold standard ,the sensitivity ,specificity and coincidence rate of genechip method was higher than those of proportion method for suscep‐tibility testing ,and the test time of genechip method was shorter than that of proportion method for susceptibility testing ,there were statistically significant differences(P<0 .05) .Conclusion Using the genechip method to detecting MTB resistance to rifampin and isoniazid has high sensitivity ,specificity and coincidence rate ,which could replace the proportion method for susceptibility tes‐ting and become an effective method .

Application of the 18F-FDG SPECT-CT combined with the images of CT in the diagnosis of lung cancer / 中国基层医药

Objective To investigate the clinical value of the 18F-FDG SPECT-CT combined with the image of CT in the diagnosis of lung cancer.Methods Retrospectively analysis images of 18F-FDG SPECT-CT and CT of 162 patients pulmonary tumor-like lesions from January 2013 to October 2013 were conducted.All the patients have been confirmed by the pathological mechanism or cytologic examination.Each patient has been firstly diagnosed by the 18F-FDG SPECT-CT along and then combined with the images of CT.The sensitive rate and the accurate rate of two methods were compared by x2 test.Results There were 40 benign lesions and 114 malignant ones in 162 patients.The sensitive rates of the two methods were 86.0％ and 96.5％ (x2 =6.63,P ＜ 0.05).The accurate rates of the two ways were 79％ and 96.3％ (x2 =7.76,P ＜ 0.05).The differences were statistically significant.Conclusion 18F-FDG SPECT-CT combined with the images of CT can increase the diagnostic sensitivity and accuracy.It has important clinical value.

Internal coincidence of serotonergic and dopaminergic oscillations modulates photo sexual responses of Japanese quail, Coturnix coturnix japonica.

Specific temporal phase relation of neural oscillations appears to be the regulator of gonadal development in many seasonally breeding species. To find out the specific phase angle of two neural oscillations that triggers gonado-inhibitory or gonado-stimulatory response, and to test the internal coincidence model, sexually immature male Japanese quail were administered with the serotonin precursor, 5-hydroxytryptophan and the dopamine precursor, L-dihydroxyphenylalanine at hourly intervals of 6, 7, 8, 9, 10, 11 and 12 h (5 mg/100 g body weight/day for 12 days under continuous condition of light, LL). Thereafter all the groups were shifted to long photoperiod (LD16:8). During post-treatment period, in general, a significant suppression of gonadal activity was seen in the 7 h and 8 h quail and an increase in the 11 h and 12 h quail compared to the control and these effects were maintained until 105 days post treatment when the study was terminated. These findings suggest that, in addition to the effects of photoperiod, the gonadal development of Japanese quail may be also modulated by internal coincidence of serotonergic and dopaminergic oscillations (induced by the administration of their precursor drugs) and the gonadal response varies depending on the time interval between the administrations of two drugs on a circadian basis. These results also demonstrate inversion of gonadal response from 7/8 h (suppressive) to 11/12 h (stimulatory) phase relation of the two oscillations and suggest that similar to photoperiodic time measurement, Japanese quail may also detect changes in the phase angle of circadian oscillations to modulate its gonadal activity.

The diagnosis value of whole body bone imaging with coincidence SPECT/CT fusion imaging for solitary“hotspots” / 重庆医学

Objective To evaluate the differentiating diagnosis value of coincidence SPECT/CT fusion imaging used in the soli-tary“hotspots”in the whole body bone imaging.Methods Fifty patients with malignancy were selected to have examination.the sensitivity,specificity and accuracy of these imaging methods were calculated by contrasting the pathology examination,CT and MRI examination,more than 6 months follow-up results between the cases.Results The sensitivity,specificity and accuracy of SPECT imaging were 94%,23%,and 63%,respectively,and that of CT were 47%,87%,66%;the sensitivity,specificity and accu-racy of SPECT/CT were 95%,80%,88%,respectively.The specificity and accuracy of SPECT/CT was significantly higher than SPECT(P<0.05)and its sensitivity and accuracy was higher than that of CT(P<0.05).Conclusion Coincidence SPECT/CT hy-brid imaging could raise the sensitivity,specificity and accuracy of diagnosis of solitary“hotspot”in whole bone imaging,which is of high clinical application value.