1.
China Pharmacy
;
(12)2005.
Article
in Chinese
| WPRIM
| ID: wpr-525597
ABSTRACT
OBJECTIVE:To prepare compound levofloxacin zinc cream and establish its quality control.METHODS:Levofloxacin zinc was made from levofloxacin and zinc sulfate,the cream was prepared by adding ground-substance to levofloxacin zinc;The content of levofloxacin was determined by ultraviolet spectrophotometry with the wavelength set at293nm.RESULTS:The prepared cream was even,fine and easy to spread;The calibration curve of levofloxacin was linear in the range of2~10?g/ml(r=0.9999,n=5),the average recovery rate was99.8%,RSD=0.44(n=5).CONCLUSION:The formulation of the preparation is reasonable and the preparation technics was simple and feasible,the quality is stable and controllable.