ABSTRACT
Condyloma lata is one of the cutaneous manifestations of secondary syphilis. They are extremely infectious, moist papules that are commonly seen on patients with secondary syphilis. Condyloma lata commonly affects the intertriginous skin, and especially that of the genitalia, the perianal area and axilla, which all suffer from heat, moisture and friction. However, they are rarely seen on the tongue. A 19-year-old male patient presented with multiple erythematous papules and plaques on the tongue. But he did not have any other cutaneous eruption. Histopathological findings revealed irregular epidermal hyperplasia and perivascular inflammatory cell infiltration with lymphocytes and plasma cells in the dermis. The VDRL and TPHA test were both positive.
Subject(s)
Humans , Male , Young Adult , Axilla , Dermis , Friction , Genitalia , Hot Temperature , Hyperplasia , Lymphocytes , Plasma Cells , Skin , Syphilis , TongueABSTRACT
Cutaneous manifestations of secondary syphilis vary widely. Nodular lesions and condyloma lata on multiple sites are an uncommon presentation. A 34-year-old man presented with a 1-month history of multiple nodules and papules on the chest and multiple erythematous whitish nodules with maceration on the perineal area and anus, oral cavity, and umbilicus. On the basis of a serologic test for syphilis and skin biopsy, nodular syphilid and condyloma lata was confirmed. We report an unusual case of secondary syphilis that presented with multiple nodular syphilid on the chest and multiple condyloma lata arising in the perineum, anus, oral cavity, umbilicus.
Subject(s)
Adult , Humans , Anal Canal , Biopsy , Mouth , Perineum , Serologic Tests , Skin , Syphilis , Syphilis, Cutaneous , Thorax , UmbilicusABSTRACT
Condyloma lata is a common manifestation of secondary syphilis, but involvement of the lip mucosa is rare. Nodular lesions, especially solitary nodules, are uncommon manifestations of secondary syphilis, and only a few cases have been described. Failure to recognize condyloma lata of the lip mucosa may delay diagnosis and treatment. A 20-year-old man presented with a 4-month history of a solitary nodule on his upper lip mucosa. A diagnosis of condyloma lata was made on the basis of serologic tests for syphilis and pathological findings. We report an interesting case of condyloma lata on the upper lip mucosa that showed an unusual clinical manifestation of secondary syphilis.
Subject(s)
Humans , Young Adult , Lip , Mucous Membrane , Serologic Tests , SyphilisABSTRACT
The number of AIDS patients is currently increasing in Korea, and multiple opportunistic infections, which are due to their immunocompromised state, have become a significant clinical problem. These opportunistic diseases may vary according to the severity of immunosuppression, the mode of transmission, the risk factors, the living environment and treatment; rectal syphilis, perianal condyloma lata and amoebic liver abscess are known to rarely develop in AIDS patients. We report here on a case of a homosexual man who simultaneously presented with an amebic liver abscess, esophageal candidiasis, chronic hepatitis B, rectal syphilis, perianal condyloma lata and asymptomatic neurosyphilis. He was treated with highly active antiretroviral therapy (HARRT) and the appropriate antiviral and antibiotic agents.
Subject(s)
Humans , Antiretroviral Therapy, Highly Active , Candidiasis , Hepatitis B, Chronic , Homosexuality , Immunosuppression Therapy , Korea , Liver Abscess, Amebic , Neurosyphilis , Opportunistic Infections , Risk Factors , SyphilisABSTRACT
Introdução: doenças sexualmente transmissíveis são verdadeiras epidemias e a sífilis vem causando danos ao longo da história, só se comparando com a aids. Objetivo: relatar três casos de sífilis em crianças, com manifestação clínica inicial de condiloma lata. Método: relato de caso por revisão de prontuários de crianças acompanhadas no Hospital Infantil Nossa Senhora da Glória. Caso 1: L, 9 anos, masculino, lesão em região anal sugestiva de condiloma lata. Avaliação médico-legal não evidenciou sinais de abuso sexual. VDRL 1:128, FTA-Abs IgG positivo e IgM negativo, líquor normal com VDRL não-reator. Mãe com VDRL 1:8, FTA-Abs IgG positivo e IgM negativo. Caso 2: G, 5 anos, feminino, lesão condilomatosa perianal, suspeita de abuso sexual não comprovada por avaliação médico-legal. VDRL 1:256, líquor normal com VDRL não-reator. Não foi realizada sorologia materna Caso 3: K, 4 anos, feminino, lesão condilomatosa perianal. Avaliação médico-legal não mostrou sinais de abuso sexual. VDRL 1:256, FTA-Abs IgM reagente, líquor normal com VDRL não-reator. Não foi realizada sorologia materna. Nos três casos não houve confirmação da classificação da doença, se congênita ou adquirida. Conclusão: há poucos dados na literatura sobre condiloma lata em crianças e o diagnóstico constitui um desafio para o pediatra, pois pode ser confundido com condiloma acuminado do papiloma vírus, por este ser mais comum. Além da importância de reconhecer a lesão condilomatosa da sífilis, é necessário dar ênfase à realização adequada da assistência pré-natal, visando reduzir os casos de sífilis congênita.
Introduction: sexually transmitted diseases are a real epidemic and Syphilis has been historically provoking terrible harm; perhaps as much harm asaids. Objective: present three cases of syphilis in children, with initial clinical manifestation caused by condyloma lata. Method: case report extracted from children's medical handbooks at Hospital Infantil Nossa Senhora da Gloria. Case 1: L, nine years old, male, lesion at anal region suggesting condyloma lata. Sexual molestation not present according to medical evaluation. VDRL 1:128, FTA-Abs IgG positive and IgM negative, normal liquor with non-reactive VDRL. Mother with VDRL 1:8, FTA-Abs IgG positive and IgM negative. Case 2: Gnb, five years old, female, Condylomatosa lesion at perianal region; sexual molestation suspicion not confirmed according to medical evaluation. VDRL, 1:256, normal liquor with nonreactive VDRL. Maternal sorology not undertaken. Case 3: K, four years old, female, aspects of Condylomatosa lesion at perianal region. Sexual molestation not present according to medical evaluation. VDRL 1:256, FTA-Abs IgG reactive, normal liquor with non-reactive VDRL. Maternal sorology not undertaken. In all three cases, the classification of the disease, congenital or acquired, was not confirmed. Conclusion: there is not many information on the medical literature regarding condyloma lata in children. Hence, it becomes a challenge to pediatricians when diagnosing such disease, mainly because it may be confused with condyloma acuminado of papiloma virus ? this being more frequent. Besides the importance of recognizing the condylomatosa lesion of syphilis, it is necessary to emphasize an adequate pre-natal assistance, aiming the reduction of congenital syphilis.
Subject(s)
Humans , Male , Female , Child , Anus Diseases/diagnosis , Syphilis, Congenital/complications , Warts/diagnosis , Prenatal Care , Warts/virologyABSTRACT
Psoriasiform lesion is rare in secondary syphilis. We report a case of psoriasiform syphilid in a 36-year-old man, who showed condyloma lata on the perianal area and multiple erythematous scaly plaques on the face, glans penis, scrotum, and both palms and soles. He had sexual contact with prostitute about 3 months ago. The differential diagnosis included papulosquamous diseases, especially psoriasis but a psoriasiform syphilid was confirmed through skin biopsies and serologic tests. The patient was treated with benzathine penicillin G 2.4 million units intramuscularly weekly for 3 weeks. After the treatment with benzathine penicillin G, the skin lesions disappeared completely.