ABSTRACT
【Objective】 To analyze the profile, preliminary screening and laboratory test results of voluntary blood donors in the past five years, so as to provide basis for formulating the recruitment strategy, ensuring clinical blood use and improving blood safety and quality. 【Methods】 789 570 voluntary blood donors from 2016 to 2020 were classified according to the category, and the positive rate of blood testing results was statistically analyzed. 【Results】 The proportion of transfusion-transmitted infections (TTI), including HBsAg, anti-HCV, anti-T, and anti-HIV, was led by HBsAg, except for anti-TP leading in 2018. The positive rate of ELISA items and ALT tests showed statistical significance by age groups(P0.05). The positive rate of preliminary screening and laboratory testing showed differences among occupation and educational background(P0.05). The number of HIV positive males (n=228) was higher than that of females(n=3), and the proportion of workers (23.08%~40.74%) and staff (16.67%~46.67%) were large. In 2020, however, the proportion of HIV infected students increased sharply to 21.62%. Sole HBV DNA positive cases was the most (n=460), while the number of sole HIV RNA(n=3) and HCV RNA positive cases (n=6) were rather low. 【Conclusion】 Targeted recruitment strategies should be formulated according to the profile and test results of voluntary blood donors to further improve blood test ability and ensure blood safety.
ABSTRACT
Objective To analyze the results of HIV antibody screening test and confirmation test results in Pudong New Area from 2014 to 2018, and to understand the situation of HIV infection in the region in recent years. Methods Samples that responded to initial screening of HIV in this jurisdiction area were tested by enzyme-linked immunosorbent assay (ELISA), chemiluminescence assay or immunochromatographic rapid diagnosis test. The samples that showed a positive response to one of the reexamination methods were subjected to confirmatory tests by Western blot assay. EXCEL and SPSS 16.0 statistical software were used to collate and analyze the data. Results Confirmatory tests were performed on a total of 2 100 retested samples. HIV positive samples were 1485 (70.7%), and HIV negative and uncertainty samples were 452 (21.5%) and 163 (7.8%), respectively. The confirmed positive male/female sex ratio was 7.95:1, and the difference was statistically significant (χ2=3.745, P<0.001). The age of confirmed positive patients was mainly 15~39 years old. The proportion of voluntary testing and counseling was the highest among the population receiving HIV tests. The positive coincidence rate between the review test and confirmation test was 91.3%. The gp160 and gp120 bands appeared most frequently in WB-confirmed positive samples, which was 100%. The gp160 band was the most frequent band of uncertain samples, accounting for 71.4%. Conclusion The positive rate was high in the confirmatory test of samples with positive results by both methods, and the samples with one negative and one positive were mostly uncertain or negative in the confirmatory test. When the results were uncertain, CD4, nucleic acid detection, and viral load detection should be used as auxiliary diagnosis.
ABSTRACT
Objective To control IDS virus (HIV)transmission through blood, provide low -risk blood donors to donate regularly, and ensure blood safety and reduce the risk of blood transfusion. Methods By analyzing HIV antibody(anti-HIV) test results, HIV infection and prevalence of blood donors from 2000 to 2009, susceptible people were identified,prevented,educated,in order to prevent the spread of HIV. Results A total of 10 years in Huainan region 361 cases of anti-HIV positive were screened out. Anti-HIV-positive of voltmtary blood donors were recognized anti-HIV positive in 4 cases ,accounting for 0.209/10 000 of the total voluntary blood donation. Epidemiological analysis in 4 cases of anti-HIV confirmed positive results: the education level of all was less than high school,75% were the local household registration ;25% were mobile population, and all were young adults, aged from 23 to 38 years;75% were workers,and 25% were temporary workers and the service sector. Conclusion By strictly blood screening to blood donation, strengthening the management, intensify propaganda against AIDS in efforts, raising people 's awareness of prevention,the spread of AIDS could be prevented and controlled.